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EVS licenses and serves third party terminology as needed to meet NCI and caBIG requirements. These vocabularies come to EVS from a variety of sources and in a variety of formats. Though the LexBIG application is able to import most of these formats directly, a few terminologies require further processing before they can be loaded. Details on terminology sources, formats and processing are provided on this page.

Locally produced vocabularies

EVS produces the following vocabularies and makes them available through the LexEVS API and various browsers (NCIt Browser, NCI Metathesaurus Browser).

Name

Source

URL for Download

Secured?

Format

Size

Processing Notes

NCI Metathesaurus

NCI Enterprise Vocabulary Services

https://cbiit.nci.nih.gov/evs-download/metathesaurus-downloads

N/A

RRF

5.4G

NCI Metathesaurus Processing

NCI Thesaurus

NCI Enterprise Vocabulary Services

https://cbiit.nci.nih.gov/evs-download/thesaurus-downloads

N/A

OWL

290M

NCI Thesaurus Processing

CTCAECommon Terminology Criteria for Adverse Eventshttp://evs.nci.nih.gov/ftp1/CTCAE/About.htmlNAOWL1MN/A

External vocabularies published by EVS

EVS makes available a number of terminologies through the NCI Browser and API that are produced by sources outside the NCI.

Chemical Entities of Biological Interest

Name

Source

URL for Download

Secured?

Format

Size

Processing Notes

Gene Ontology

Gene Ontology Consortium

ftp://ftp.geneontology.org/pub/go/ontology-archive/

N/A

OBO

12M

None

HL7

Health Level Seven

http://www.hl7.org/Library/data-model/RIM/modelpage_mem.htm

N/A

RIM database

32M

None

NDF-RT

Department of Veterinary Affairs

http://216.47.169.155/support/users/default.asp

Yes

OWL

4M

Converted from Ontylog to OWL by Lockheed Martin

The MGED Ontology

MGED Society

http://mged.sourceforge.net/ontologies/MGEDOntology.owl

N/A

OWL

1M

None

UMLS

Unified Medical Language System

http://www.nlm.nih.gov.../umlsknowledgesources.html

Requires Free UMLS License

RRF

22G

See UMLS Subsets table below

UMLS SemNet

UMLS Semantic Network

http://semanticnetwork.nlm.nih.gov/Download/index.html

N/A

RRF

1M

None

Zebrafish

The Zebrafish Model Organization Database

http://obo.cvs.sourceforge.net/..../zebrafish_anatomy.obo

N/A

OBO

1M

None

ChEBIChemical Entities of Biological Interestftp://ftp.ebi.ac.uk/pub/databases/chebi/ontology/chebi.oboN/AOBO1MNone
Mouse AnatomyMouse Adult Gross Anatomyftp://ftp.informatics.jax.org../adult_mouse_anatomy.oboN/AOBO1MNone
HGNCHugo Gene Nomenclature Committee Ontologyftp://ftp.ebi.ac.uk/pub/databases/genenames/hgnc_complete_set.txt.gzNAFlat1MConvert to OWL
OBIOntology for Biomedical Investigationshttp://svn.code.sf.net/p/obi/.../merged-obi-comments.owlNAOWL1MNone

UMLS subsets published by EVS

The UMLS is not published in entirety. Instead a number of subset ontologies are extracted and published.

Name

Original Source

Secured?

Size of subset

Processing Notes

LOINC

Logical Observation Identifiers Names and Codes

N/A

500M

None

MedDRA

Maintenance and Support Services Organization

Requires MSSO Subscription

193M

None

Snomed

International Health Terminology Standards Development Organization

Requires Snomed license

7.4G

None

ICD9The International Classification of Diseases Ninth RevisionN/A180MNone
ICD9CMThe International Classification of Diseases Ninth Revision Clinical ModificationN/A210MNone
ICD10The International Classification of Diseases Tenth RevisionN/A121MNone
ICD10CMThe International Classification of Diseases Tenth Revision Clinical ModificationN/A285MNone
PDQPhysicians Data QueryN/A160MNone
RadLexhttp://www.rsna.org/radlexN/A179MNone
     
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