View Source

Date

07 Mar 2022

Attendees

Committee Member	Present	Absent
Kuffel, Gina (NIH/NCI) [C]	X
Musk, Philip (NIH/NCI) [C]	X
Unknown User (wak11@duke.edu.commons)	X
Kim, Erika (NIH/NCI) [E]		X
Gregory Tawa		X
William Hendriks		X
Matthew Breen	X
Roel Verhaak	X

Goals

Review, discuss, and prioritize ICDC study submission proposals

Outstanding Action items

Determine if Matthew Breen will speak at next Steering Committee meeting about possibilities for cross-referencing data about WGS, WES, airborne contaminants, pathology, etc. and a central repo for canine data as it relates to all comparative mechanisms (let's push this out to not the next, but the Steering Committee meeting on x date). Targeting June presentation.

Discussion items

Item	Who	Notes
Testing Access to Files in SharePoint	Kuffel, Gina (NIH/NCI) [C]	ICDC SharePoint site
New Data Submission Request: Inhaled IL-15 Immunotherapy for Treatment of Lung Metastases	Kuffel, Gina (NIH/NCI) [C]	Submission request materials
Test case for Osteosarcoma data from candidate publication list will be recommended to the SAC when clinical metadata is received	Kuffel, Gina (NIH/NCI) [C]	Modiano Osteosarcoma paper Candidate publication list
Data Use Guidelines (DUG) and Intellectual Policy Statement	Kuffel, Gina (NIH/NCI) [C]	Link to Data Use Guidelines in SharePoint
Study Updates	Musk, Philip (NIH/NCI) [C]	15 TB of data transfer from UGA is complete Study Released on 2/28/22: UBC01 - Antitumor Activity and Molecular Effects of Vemurafenib in Dogs with BRAF-mutant Bladder Cancer Adds 170 files (~320 GB) UBC01 & UBC02 share 7 canines, 3 tumor bearing dogs and 4 controls, this activates multi-study matching on production.

Minutes (Not Verbatim)

WK - How do we get other ICs involved in participating in ICDC expansion? Maybe a working group for data integration for ICDC? Greg is a rep for NCATS.

MB - Potentially formalize the plan in the minutes of Steering Committee, formalize an action item for Toby and others.

WK - Expand lifespan of companion animals, perhaps there can be a coalition.

MB - Business plan for ICDC including aims, costs, etc. Invite the involvement of other ICs

WK - Is the nanostring data/devices able to produce whole transcriptome data? (Nanostring recently released software update that enables whole transcriptome data).

Action items

Matthew & Warren to write an email request to Toby pertaining to formalization of a business plan for ICDC.
Musk, Philip (NIH/NCI) [C] to brush up on Nanostring documentation.