Committee Member | Present | Absent |
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X | ||
X | ||
X | ||
X | ||
X | ||
Debbie Knapp | X | |
Toby Hecht | X | |
https://nih.sharepoint.com/sites/NCI-CBIIT-FNL-ICDC-ICDCLeadershipGroups
Item | Who | Talking Points |
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DGAB Updates |
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BPSC Updates |
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September Steering Committee Updates |
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ICDC Site Updates |
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ICDC Next Phase Planning |
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TH - Will the PRECINCT program name remain the same, the reference is not indicative of the personnel or timeframes
CS - Maintaining an all-inclusive approach is the recommendation.
TH - Should we invite new PRECINCT members to the ICDC SC meeting? Previously we had Renee and Cheryl. Debbie is a constant and new awardee. People with database experience may be valuable to have.
CS - Jaime Modiano would be a good fit.
AL - Well-connected, asks great question, very introspective, good choice to invite Modiano.
CS - Other candidates would be David, Paul, Nikki, not sure of database experience.
TH - RFI response from Germany requesting circulating tumor cell data.
1. Genomic correlates across platforms (DNA, RNA, protein).
2. Correlating multi-omics data with clinical annotation and phenotypes, particularly outcomes.
3. Comparative analyses of canine and human. Examples include:
1. Search for conserved mutations between canine and human tumors
2. Disease diagnosis (e.g. cancer type) and classification mapping between canines and humans
5. Gene expression changes and mutational profiles associated with therapeutic response and outcome
6. How do sporadic tumors in non-human mammals compare to sporadic human tumors?
7. Correlations and model building from radiomic and pathomic features extracted from medical and histopathologic images with outcomes and genomics, as is currently being widely done with human images
8. Develop biomarkers of response and resistance in humans by analyzing the responses and genomic signatures in dogs.
TH- Possible COI with people working on the RFI and then responding to the RFI. Dr. Doroshow signed off on RFI. Unless there are issues noted the RFI should be published in ~ 2 weeks. Many ideas came from initial focus groups.
JO- What type of plans can be put in place to advertise the RFI? Can we leverage NCI social media?
TH- We can send to anyone we want, including Cancer Center Directors, they have collaborations with vet clinic schools, some of the foundations.
AL- Circulate to PRECINCT as well.
TH- Deadline for response is Dec. 1st.
AL- Giving presentation to the children's oncology group. Touched base with CIN and PRECINCT. The talk is osteo-focused.
Action items