COTC021: Evaluation of Orally Administered mTOR inhibitor Rapamycin in Dogs in the Adjuvant Setting with Osteosarcoma
This is the parallel arm to COTC022: SOC in dogs with Osteosarcoma that was previously uploaded to the ICDC
Clinical data for 152 dogs. mRNAseq for 93 dogs
Status: Approved by SAC on 6/30/23, Template-based data loading files have been received
UBC03
Approved by SAC on 8/13/22
"Transcriptomic analyses of early stage bladder cancer in Scottish Terriers detected through screening"
Purdue University
19 cases
Status: v2 template-based data loading files have been reviewed, v3 files have been received
OSA02
Approved by SAC on 9/22/22
"Immune Pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma"
Colorado State University
108 cases
Status: Submitters generating template-based loading files, reviewing hospital records to extract staging information and progression/survival data
ORGANOIDS01
Approved by SAC on 9/22/22
“Characterization of healthy and diseased canine tissues and organoids"
Iowa State University
Status: Loaded into the Dev environment and indexing to be submitted to DCF this week, data preview conducted, embargo lifted, in the hands of QA team.
PRECINCT01
Approved by SAC on 6/28/22
"Inhaled IL-15 Immunotherapy for Treatment of Lung Metastases"
UC Davis
21 cases
Status: Most data not yet available, pathology reports have been fully redacted and adverse event metadata coming soon, some files have been transferred, bucket permissions resolved, cytokine data is now available
PRECINCT02
Approved by SAC on 12/8/22
"Novel treatments for Diffuse large B cell lymphoma (DLBCL) in dogs"
Tufts University
49 cases
Status: Submitter has generated version 2 of template-based data loading files
PANCAN01
Approved by SAC on 11/8/21
"Canine tumor mutational burden is correlated with TP53 mutation across tumor types and breeds"
University of Georgia
684 cases
Status: Submitters generating template-based loading files, data manager PoC has been identified, candidate study has been identified to move forward
Minutes (Not Verbatim)
WK - let move the Auburn study to a formal vote within DGAB.
Warren and Greg have voted in favor, Gina to collect votes from other members through email.
Action items
Full publication details needed from Matthew Breen for UC01