Stakeholders:
Natalie Kuzla, Program Manager for PRECINCT
Jim Dattilo, Senior Clinical Data Manger for PRECINCT
Qi Long, PI
Nicola (Nikki) Mason
Data Types Collected:
Data collected in PRECINCT:
Clinical trial data/observations
Genomic DNA sequence (including cfDNA) – WES, WGS
RNA sequence
qRT-PCR (e.g. for cytokines)
Flow cytometry (surface antigens for tumor and immune phenotyping, intracellular markers and cytokines)
Immunohistochemistry (tumor, LN biopsies)
Cytokine/chemokine levels (ELISA, EliSpot)
Imaging – MRI, PET
Proliferation assays (CFSE)
Cytotoxicity assays (51Cr release)
ADCC assays
Virus Titers (HSV)