Date
Attendees
Committee Member | Present | Absent |
---|---|---|
X | ||
Amy Leblanc | X | |
X | ||
X | ||
Debbie Knapp | X | |
Toby Hecht | X | |
Ralph Parchment | X |
Goals
- Discuss updates to ICDC and define emerging strategies and priorities
SharePoint Site
https://nih.sharepoint.com/sites/NCI-CBIIT-FNL-ICDC-ICDCLeadershipGroups
Outstanding Action Items
- Revisit new steering committee members in September (loop Connie into this discussion)
Agenda
Item | Who | Talking Points |
---|---|---|
New Steering Committee Members | ||
Post Discussion about FidoCure | All | |
New ICDC Subcommittee: Longitudinal Data Acquisition and Use Working Group (LDAUWG) Purpose: Formulate scientific questions and use cases that can be used to interrogate longitudinal datasets that would justify the ingestion of such data into the ICDC.. | All |
|
DGAB Updates | ICDC Studies in Active Submission
| |
ICDC Biospecimen Data |
| |
Upcoming Steering Committee Meeting | Ralph Parchment |
|
Minutes (Not Verbatim)
Previous ICDC Use Cases from Steering Committee
1. Genomic correlates across platforms (DNA, RNA, protein).
2. Correlating multi-omics data with clinical annotation and phenotypes, particularly outcomes.
3. Comparative analyses of canine and human. Examples include:
1. Search for conserved mutations between canine and human tumors
2. Disease diagnosis (e.g. cancer type) and classification mapping between canines and humans
5. Gene expression changes and mutational profiles associated with therapeutic response and outcome
6. How do sporadic tumors in non-human mammals compare to sporadic human tumors?
7. Correlations and model building from radiomic and pathomic features extracted from medical and histopathologic images with outcomes and genomics, as is currently being widely done with human images
8. Develop biomarkers of response and resistance in humans by analyzing the responses and genomic signatures in dogs.
Action items
- Toby to invite Greg from CCDI to the next Executive Team Meeting in January
- Toby to look across the NCI directory to find person that has a combination of canine and pediatric oncology background
- John to get disease areas from Sam V.
- Toby to reach out to Adam Resnick