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Blog from March, 2014
SYNOPSIS: The NCI Mouse Models of Human Cancers Consortium has provided a focus on animal cancer models for the last 15 years. However, the program ends in 2014, and a new entity is needed to extend the outreach and educational aspects of the Consortium to support new directions for translational applications of animal models. Dr. Marks will describe a new NCI program, an open Oncology Models Forum. The Forum will provide the cancer research community with a comprehensive resource for information to guide generating, validating, and credentialing new models, informing their practical uses, advancing modeling techniques, and providing catalogs of available models-related resources, programs, and services. The goal of the Forum program will center on effective, reliable use of mice, mouse models, and human-in-mouse models in translational cancer research. Key to the success of the Forum will be use of the HubZero® platform to enable collaborators from anywhere to work together on common problems that pertain to animal models.
BIO:
Dr. Cheryl Marks is Associate Director of the NCI’s Division of Cancer Biology, and manages the NCI Mouse Models of Human Cancers Consortium. Dr. Marks received her Ph.D. in biochemical genetics from the George Washington University, and post-doctoral training in the National Institute of Neurological Disorders and Stroke (NINDS) intramural program. She joined the NCI as a program director in 1987.
SUMMARY:
Topic: The Oncology Models Forum: An Interactive Platform for Collaborative Translational Research
Speaker: Cheryl Marks, Ph.D., Division Associate Director, NCI Division of Cancer Biology
Date: Wednesday, April 2, 2014
Time: 11 AM – 12 PM EDT
You are invited to listen to Dr. Marks' presentation in Room 2W908 in the NCI Shady Grove Building on Medical Center Drive or via WebEx.
Presentation: A screen cast of the presentation will be available for viewing after the event here on our Speaker Series Videos page and on the NCI CBIIT Speaker Series YouTube Playlist 
. The presentation slides are also attached.
About the NCI CBIIT Speaker Series:
The National Cancer Institute (NCI) Center for Biomedical Informatics and Information Technology (CBIIT) Speaker Series is a bi-weekly knowledge-sharing forum featuring both internal and external speakers on topics of interest to the biomedical informatics and research communities. For additional information, including past speaker series presentations, visit the CBIIT Speaker Series page.
Questions? Please email us at NCICBIITcomms@mail.nih.gov.
Individuals with disabilities who need reasonable accommodation to participate in this program should contact the Office of Space and Facilities Management (OSFM) at 240-276-5900 or the Federal TTY Relay number 1-800-877-8339.
SYNOPSIS:Cancer is a complex group of diseases with many causes. Genetic changes and epigenetic alterations in somatic tissues, as well as germ line mutations or risk alleles, all contribute to cancer development and progression. Dr. Lee will present integrated studies of breast, esophageal, and gastric cancers through collaborative research with many investigators in CCR and DCEG. He will discuss a broad range of topics: from GWAS to whole genome sequencing studies; from genomics to functional studies; from genes to signature studies; from experiments to computational analyses; and from data to knowledge discovery. Dr. Lee will talk about how interweaving high-throughput data with bioinformatics analyses enables us to gain a better understanding of cancer biology and etiology.
BIO:
Dr. Maxwell Lee is the head of the high-dimension data analysis group at NCI’s Center for Cancer Research (CCR). Dr. Lee’s group conducts collaborative research with many investigators at CCR and the Division of Cancer Epidemiology and Genetics (DCEG). The group focuses on bioinformatics analyses of high-throughput data. His research spans multiple domains, including cancer genomics and epigenomics, population genetics and epidemiology, allelic-specific gene expression and epigenetic modifications, and computational methods. Dr. Lee has published more than 60 peer-reviewed papers. He serves as an Associate Editor for BMC Cancer and is on the committees of TCGA DAC, iNCI DAC, CCRIFX RPC, and NCIP High-throughput Molecular Data Working Group.
Dr. Lee received his B.S. from the University of Science and Technology of China, Ph.D. in Biochemistry from Duke University, and completed postdoctoral training at the Johns Hopkins University School of Medicine. He joined the NCI as a tenure-track investigator in 2000.
SUMMARY:
Topic: Integrated Studies of Breast, Esophageal, and Gastric Cancers Using High-Throughput Technologies and Computational Analyses
Speaker: Maxwell Lee, Ph.D., NCI Center for Cancer Research
Date: Wednesday, March 19, 2014
Time: 11 AM – 12 PM EST
You are invited to listen to Dr. Lee's presentation in Room 2W908 in the NCI Shady Grove Building on Medical Center Drive or via WebEx.
Presentation: Download the PPT presentation. A screen cast of this presentation is not available.
About the NCI CBIIT Speaker Series:
The National Cancer Institute (NCI) Center for Biomedical Informatics and Information Technology (CBIIT) Speaker Series is a bi-weekly knowledge-sharing forum featuring both internal and external speakers on topics of interest to the biomedical informatics and research communities. For additional information, including past speaker series presentations, visit the CBIIT Speaker Series page.
Questions? Please email us at NCICBIITcomms@mail.nih.gov.
Individuals with disabilities who need reasonable accommodation to participate in this program should contact the Office of Space and Facilities Management (OSFM) at 240-276-5900 or the Federal TTY Relay number 1-800-877-8339.
