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CTRP Pragmatic Trial Value

Indication

Yes

This is a pragmatic trial

No

This is not a pragmatic trial

No Data Available

Pragmatic trial indicator not currently set on the CTRP trial record


Pragmatic Clinical Trials Definition: A clinical trial that is designed to study a health intervention in a real-world setting that is similar or identical to the one in which the intervention will be implemented

CTRP classifies trials with the following characteristics as pragmatic:

  • Unit of randomization may be other than an individual participant (e.g., the clinic, the healthcare system, or a neighborhood if a community setting)
  • Intervention may be multi-level involving changes to:
    • Participant behavior (e.g., completing a symptom report measures online), and
    • Provider behavior (e.g., receiving the participant’s symptom report and having to act on it)
  • Data are often obtained directly from medical records and, are likely collected on a large number of participants
    • Data may be collected during a pre-intervention period and again during a post-intervention period in each clinic that is randomized
    • Participants for whom data are collected in the pre-intervention period may not be the same ones for whom data are collected in the post-intervention period
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