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Date

Attendees



Goals

  • Review, discuss and prioritize ICDC study submission proposals

Outstanding Action items

Discussion items

ItemWhoNotes
Study Updates
  • GLIOMA01- 77 VCF files and 77 TBI files released, case associated files
  • MGT01 - study released, 2 publications included in study record, WES, WGS, RNA-Seq data
  • COTC022 - study released including study protocol, sequencing data not yet available
  • OSA01 -  problem with tar file, pre-release demo should happen soon
  • UBC02 -  embargo lifted, permissions issues related to indexing caused delay. No pub_id available
  • UBC01 - embargo expected to be lifted soon
  • UBC03 -  follow up with the Knapp group is required
  • PanCan - data ingestion process to begin soon
Test case for Osteosarcoma data from candidate publication list will be recommended to the SAC.
Data Transfer Agreement (DTA)Kuffel, Gina (NIH/NCI) [C]
Next DGAB Meetings
  • Dec. 20th
  • Jan 3rd
  • Jan 17th- MLK federal holiday

Minutes (Not Verbatim)

MB- ICDC should be considered as a potential hub for data beyond Cancer (Golden Retriever lifetime study). Knowing there is an incredible interest in data harmonization across datasets, may help Toby. This may help to attract funding beyond NCI. DGAB should consider inviting epidemiologists, environmentalists, etc. to plan to provide information and possibilities for curation and harmonization.

WK- Toby has asked Rod Page and Dan Promislow to interface with the ICDC SC. 

MB- The dog is not just an model for cancer and aging, but also environmental.

WK- If you are willing to speak at the next SC meeting on this topic..

RV- What does this mean practically speaking?

MB- Most people are generating clinical metadata and outcomes associated with environmental factors, opportunity to add cases for dogs from different part of the nation. This could cross-reference data about WGS, WES, airborne contaminants, pathology, etc. Harmonize data, not just genomics data, for canine. Surely better for everybody if there was a central repo for canine data as it relates to all comparative mechanisms.

RV- Dog is a model for enviro-immunity.


Action items

  • Kuffel, Gina (NIH/NCI) [C] to send out new invite for DGAB meeting at the same time 12-1, for Dec. 10th (maintain 2nd & 4th Mondays)