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Date

Attendees

Committee MemberPresentAbsent
Kuffel, Gina (NIH/NCI) [C]
X

Musk, Philip (NIH/NCI) [C]

X
Warren KibbeX
Kim, Erika (NIH/NCI) [E]

X
Gregory TawaX
William HendriksX
Matthew Breen
X
Roel Verhaak
X



Goals

  • Review, discuss, and prioritize ICDC study submission proposals

Outstanding Action items

  • Matthew & Warren to write an email request to Toby pertaining to formalization of a business plan for ICDC.
  • Musk, Philip (NIH/NCI) [C] to brush up on Nanostring documentation.

Agenda

Discussion ItemWhoNotes
New data submission request

Kuffel, Gina (NIH/NCI) [C] 

  • "Immune Pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma" 
  • Data Submission Folder: OSA-Normal
PRECINCT Data Request Submission: Inhaled IL-15 Immunotherapy for Treatment of Lung Metastases

All

Review of other Modiano publications: Other Modiano Publication Considerations.xlsx

Kuffel, Gina (NIH/NCI) [C]

Study Updates

Musk, Philip (NIH/NCI) [C]

  • TCL01
    • Study identifier changed to TCL01 (Tumor Cell Line)
    • In the hands of the testing team
    • Pending release record available on production
    • 6 study files being assembled
  • PRECINCT
    • Program now available on lower tier (dev environment)
    • Study record is in place
  • PANCAN01 (15 TB Re-analysis)
    • Data is already in a ICDC S3 bucket
    • Study onboarding on the horizon

Minutes (Not Verbatim)

Voting on TP53 Osteosarcoma study from Colorado State: Warren approves, Will approves, Greg approves

Phil- Jim has pulled data loading templates from the ICDC web application. Waiting to meet with UC Davis to finish data onboarding to show them what we have done with the study and contrast it with the 2 Purdue studies to give them an idea of the type of data expected. We also will need high-level sign off from the PRECINCT program for the program record represented on ICDC. There is another group part of PRECINCT that will be providing a data submission request soon. 

Phil- Bulk of TCL01 study will be on the QA tier by this afternoon. 

Phil- Working on approach for PANCAN01 study, there are 10-12 different studies involving ~500 dogs. Shaying's group will leverage the data loading templates and the Data Model Navigator to provide us populated data loading templates with a bit of hand-holding from myself.


Action items