Use Case ID | Area | Use Case | Submitter | Date Completed |
---|---|---|---|---|
1 | Cloud Resources | Genomic correlates across platforms (DNA, RNA, protein). | Steering Committee | |
2 | Cloud Resources | Correlating multi-omic data with clinical annotation and phenotypes, particularly outcomes. | Steering Committee | |
3 | Cloud Resources | Comparative analyses of canine and human. For example, search for conserved mutations between canine and human tumors | Steering Committee | |
4 | Cloud Resources | Biological pathway similarities and differences between canines and humans, how that informs therapeutic choices, and when canines and humans respond the same and when differently. | Steering Committee | |
5 | Cloud Resources | Gene expression changes and mutational profiles associated with therapeutic response and outcome | Steering Committee | |
6 | Cloud Resources | How do sporadic tumors in non-human mammals compare to sporadic human tumors? | Steering Committee | |
7 | Cloud Resources | Correlations and model building from radiomic and pathomic features extracted from medical and histopathologic images with outcomes and genomics, as is currently being widely done with human images | Steering Committee | |
8 | Cloud Resources | Can we develop biomarkers of response and resistance in humans by analyzing the responses and genomic signatures in dogs? | Steering Committee | |
9 | Cloud Resources | Correlate data across multiple data commons for analysis (e.g., pull images for analysis from the Imaging Data Commons, the ICDC, and any other commons that might come into play where they share some common parameter, like response to a certain drug). | Steering Committee | |
10 | Internal | Documentation/Software should be developed to help the users transform and submit their data to the system in a user-friendly, easy-to-use fashion. | M. Beyers | |
11 | Internal | Users should be able to store images, sequences (DNA/RNA/protein) in the system as part of their upload. Included in this is a need to be able to upload to an S3 bucket that is connected to the system. | M. Beyers |