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This sub-project addresses the lack of uniformly accepted standards within digital pathology and the simultaneous need for integration of pathology data with radiographic, genomic, and proteomic data. Its mission is to create an open-source digital pathology image server that can host and serve digital pathology images for any of the major vendors without recoding, facilitating data integration. This image server would establish an informatics and IT infrastructure to implement pilot challenges for clinical and pre-clinical studies that integrate the (CKK: talk to Ulli about different names for the same? domains mentioned on this page) genomics, diagnostic imaging, and digital pathology domains.
Goals: data exploration, data connection, data mashup, make data available for analysis, make data accessible for image algorithms
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ii) Extend software to support data mashups between image-derived information from TCIA and clinical and molecular metadata from TCGA.
Histopathology
•Incorporate Openslide with caMicrosocope enabling caMicrosocope to directly serve whole slide pathology images from the majority of digital pathology vendors.
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Extend software to support data mashups between image-derived information from TCIA and clinical and molecular metadata from TCGA.
Integrative Queries
Programmatic Access to Data to TCGA-related image data.
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AIM 2: TCGA Infrastructure Ported to/applied to Co-clinical Setting
•Improve small-animal DICOM compliance
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