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| Sub-Project Name | Description |
|---|---|
| Digital Pathology and Integrated Query System | Address Addresses the interoperability of digital pathology data, improve improves integration and analytic capabilities between TCIA and TCGA, and raise raises the level of interoperability to create the foundation required for pilot demonstration projects in each of the targeted research domains: clinical imaging, pre-clinical imaging, and digital pathology imaging. |
| DICOM Standards for Small Animal Imaging; Use of Informatics for Co-clinical Trials | Address Addresses the need for standards in pre-clinical imaging and test tests the informatics created in the Digital Pathology and Integrated Query System sub-project for decision support in co-clinical trials. |
| Pilot Challenges | Challenges will be designed to develop knowledge-extraction tools and compare decision-support systems for the three research domains, which will now be represented as a set of integrated data from TCIA and TCGA. The pilot challenges would use limited data sets for proof-of-concept, and test the informatics infrastructure needed for more rigorous “Grand Challenges” that could later be scaled up and supported by extramural initiatives. |
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With small animal/co-clinical data meeting the DICOM standard, researchers could find a mouse with the same kind of tumor and compare its response to various therapies that could help generate sophisticated diagnoses and treatment plans.
Pilot Challenges
1) AIM 3 - “Pilot Challenges” to compare The Pilot Challenges sub-project is unique within CTIIP because rather than contributing to data integration goals, it demonstrates that integration by comparing the decision support systems for three clinical imaging research domains: Clinical Imaging, Preco-clinical Imagingimaging, and Digital Pathologydigital pathology.
a) Leverage and extend the above platform and data systems to validate and share algorithms, support precision medicine and clinical decision making tools, including correlation of imaging phenotypes with genomics signatures. The aims are fashioned as four complementary “Pilot Challenges”.
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