Page History
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- Access a sample and composition.
To enter data or add files pertaining to the nanomaterial component of the sample, click the All or Nanomaterial Entity tab and click Add next to Nanomaterial Entity. Both tabs display five sections, but the All tab provides customizations based what you select in the Nanomaterial Entity Type* field.
Include Page Other options Other options Follow these steps to fill in the composition. Links are provided for additional details.
Anchor AddNanoMaterialEntity AddNanoMaterialEntity Section What to Do Nanomaterial Entity Type* Fill in the entity type (required) and add a Description for the entity.
[Nanomaterial] Properties Fill in the customized information according to what you selected for Nanomaterial Entity TypeBased on the Entity Type, fill in the appropriate Properties. Composing Elements Add information regarding the elements that compose the nanomaterial entity of the sample. File Click Add to expand the page to add one or more files whose data is relevant to the nanomaterial entity or the derivation of its data.
Copy to other samples with the same primary organization? Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact. When you finish, click Submit to save the data to the sample.
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Defining Nanomaterial Entity Properties
The following nanomaterial entity types can be selected in the Nanomaterial Entity Summary. Once selected, a Property section appears on the page. You can describe properties for each type by following these links.
If you select one of the following Nanomaterial Entity Types, the Properties section opens and you must fill in additional information.
- Biopolymer
- Carbon
- Biopolymer
- Carbon Nanotube
- Dendrimer
- Emulsion
- Fullerene
- Liposome
- Metal Particle
Info More information is provided about the Quantum Dot
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entity type, but you do not have to fill in additional properties.
Biopolymer
A biopolymer nanoparticle is a type of polymer that is produced by living organisms. In the context of nanotechnology, a biopolymer can also be a nanomaterial entity or a functionalizing entity.
Define Fill in the biopolymer properties.
Field | Description | ||||||
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Name | Enter the name of the biopolymer. | ||||||
Bipolymer type |
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Sequence | Using the appropriate format, enter the complete sequence of the biopolymer. |
Continue below to define carbon nanotube information.
Carbon Nanotube
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Field | Description |
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Average Length | Enter the average length of the nanotube. |
Length Unit | Select or enter the measurement unit type for the average length measurement of the nanotube. |
Chirality | The spatial position or orientation of functional groups located within a molecule. Enter information about the chirality in the nanotube and its effect on the orientation of functional groups located on the particle. |
Diameter | Enter the measurement of the nanotube diameter, as measured from one side of the tube wall through the center of the nanotube to the opposite point on the circumference. |
Diameter Unit | Enter the measurement unit type of the nanotube diameter. |
Wall Type | Select the appropriate description of the nanotube wall.
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Continue below to define dendrimer information.
Dendrimer
A dendrimer is a polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through iterative reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.
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Field | Description |
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Branch | Branches are molecules that branch off of the core (like tree branches). Enter a description that represents the number of branches in the dendrimer. |
Generation | Generations are shells layered on the core of a dendrimer. Dendrimers consist of layers of chemical shells built on a core module. Each shell consists of two chemicals in the same order (A-B) and each shell is called a generation. The generations are labeled in decimal to illustrate the shell layering/consistency. For example, Generation 2.5 (G2.5) = 1 shell of A-B (1), surrounded by a second shell of A-B (2), topped off with only one chemical A within the shell (.5). As such, the layering structure would be (A-B, A-B, A) = 2.5. List the generations reflected in this dendrimer. |
Continue below to define Emulsion information.
Emulsion
An emulsion is a suspension of liquid within another liquid or a dispersion consisting of two or more liquid phases. In the context of caNanoLab, an emulsion nanoparticle consists of nanoparticles suspended in an emulsifying liquid.
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Field | Description |
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Is Polymerized* | Specify whether the composition is polymerized. Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers). |
Polymer Name* | Enter the name of the polymer suspended in the emulsion. |
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Fullerene
A fullerene is one of three known pure forms of carbon that exhibits a spherical shape with a hollow interior; named after Buckminster Fuller. The number of carbon atoms comprising fullerenes is variable; several stable spherical carbon structures containing 70 or more atoms have been documented.
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Field | Description |
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Average Diameter | Enter themeasurement of the fullerene diameter, as measured from one side of the nanoparticle through its center to the opposite point on the circumference. |
Average Diameter Unit | Enter the measurement unit type of the fullerene diameter. |
Number of Carbons | Enter the number of carbon molecules comprising the fullerene. |
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Liposome
Liposomes are substances composed of layers of lipid that form hollow microscopic spheres within which drugs or agents could be contained for enhanced safety and efficacy. Based upon its size measured in nanometer range, a liposome can be categorized as a nanoparticle.
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Field | Description |
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Polymer Name | Enter the name of the liposome polymer. |
Is Polymerized | Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers). Select Yes or No, reflecting whether or not the liposome is polymerized. |
Continue below to define metal particle information.
Metal Particle
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Field | Description |
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Initiator | Enter the agent that initiated the polymerization. Examples are free radicals or peroxide. |
Is crosslinked | Crosslinking is a covalent bond between two polymers or two different regions of the same polymer. Select Yes or No, indicating whether the polymer is crosslinked. |
Crosslink Degree | Enter the percentage level of covalent linkage in the polymer. |
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Quantum Dot
A Quantum Dot is a nanometer-sized semiconductor particle, made of cadmium selenide (CdSe), cadmium sulfide (CdS) or cadmium telluride (CdTe) with an inert polymer coating. The semiconductor material used for the core is chosen based upon the emission wavelength range being targeted: CdS for UV-blue, CdSe for the bulk of the visible spectrum, and CdTe for far red and near-infrared. The size of the particle determines the exact color of a given quantum dot. The polymer coating protects cells from cadmium toxicity but also facilitates the attachment of a variety of targeting molecules, including monoclonal antibodies directed to tumor-specific biomarkers. Because of their small size, quantum dots can function as cell- and even molecule-specific markers that will not interfere with the normal cellular functions.
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Field | Description | ||||||
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Composing Element Type* | Select from the drop-down list the type of composing element comprising this nanomaterial (required).
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Chemical Name* | Enter the chemical name given to the atomic or molecular structure that composes the center of the nanoparticle (required). | ||||||
Crosslink Degree | Enter the percentage level of covalent linkage in the polymer. | ||||||
PubChem Data Source/PubChem ID |
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Amount/Amount Unit |
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Molecular Formula Type |
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Molecular Formula | Enter the chemical formula of the nanoparticle. | ||||||
Description | Enter a description for the composing element. | ||||||
Inherent Function | Inherent function is the characteristic behavior of a sample that results from the chemical and physical composition and properties of the entity. Click the Add button to expand the page where you can enter this information. | ||||||
Function Type |
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Description | Enter any additional function information for the nanomaterial entity that the form does not already include. |
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- Access a sample and composition.
To enter data or add files pertaining to the nanomaterial component of the sample, click the All or Functionalized Entity tab and click Add on the Physico-chemical Characterization bar. Both tabs display five sections, but the All tab provides customizations based what you select in the Functionalized Entity Type* field.
Include Page Other options Other options Follow these steps to fill in the composition. Links are provided for additional details.
Anchor AddFunctionalizedEntity AddFunctionalizedEntity Section What to Do Functionalized Entity Type* Fill in the entity type (required).
[Functionalizing Entity] Properties Fill in the customized information according to what you selected for Functionalized Entity TypeBased on the Entity Type, fill in the appropriate Properties. Inherent Function Information Add information about the functionalizing elements of the sample. File Click Add to expand the page where you can add one or more files whose data is relevant to the functionalizing entity or the derivation of its data.
Copy to other samples with the same primary organization? Select one or more samples in the list to which you want this composition data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact. When you finish, click Submit to save the data to the sample.
Defining
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[Functionalizing Entity
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type] Properties
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If you select one of the following Functionalizing Entity Types, the Properties section opens and you must fill in additional informationFill in the following functionalized entity information as needed.
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Field | Description |
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Antibody |
Select from the following fields: |
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When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.
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Biopolymer | Select from the following fields.
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Small Molecule | Add an Alternate Name for the Small Molecule. |
Defining
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a Functionalizing Entity
Fill in the following functionalized entity information as needed.
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The [Funtionalizing Entity Type] Properties section opens for some Functionalizing Entity types as you make that selection.
Fill in the following properties for each unique functionalizing entity.
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Field | Description | ||||||
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Chemical Name | Enter the chemical name for the functionalizing entity whose type you just selected. | ||||||
PubChem Data Source/PubChem ID |
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Amount/Amount Unit |
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Molecular Formula Type |
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Molecular Formula | Enter the chemical formula of the functionalizing entity. | ||||||
Activation Method |
Select from the drop-down |
menu the method used to activate the functionality of the sample. |
Select from the following fields.
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Activation Effect | Enter the functional effect of the entity. | |
Description | Enter any additional composition information that the form does not include. |
When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.
Continue to define functionalizing entity propertiesContinue to define function information.
Defining Function Information
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