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Co-chairs
Gabriela Riscuta: gabriela.riscuta@nih.gov
Konstantin Salnikow: salnikok@mail.nih.gov
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Up-coming conference Registration
Age-Dependent Changes in Cancer Biology
October 26-27, 2020
Virtual Conference
The conference was announced for an in-person meeting ( April 2-3, 2020) and it is being rescheduled to a virtual meeting due to COVID-19.
Draft Agenda
D10:00 am – 10:05 am ay Day 1, October 26, 2020 2020
10:00 am |
RegistrationDay 1, 2020
– 10:05 am | Introduction and Overview Gabriela Riscuta |
NCI/DCP |
10: |
05 am - |
10: |
20 am | Opening Remarks: Ned Sharpless |
NCI |
10: |
20 am - |
10: |
35 am | Opening Remarks: Richard Hodes |
NIA | |
10:35 am -11:05 am | Keynote Speaker: Luigi Ferrucci, |
NIA |
11: |
05 am - 11: |
45 am | Understanding the Molecular Biology of Cancer in Elderly Moderator: Max Guo NIA |
11: |
05 am - |
11: |
25 am | Anticancer mechanisms in long-lived mammals Vera Gorbunova (University of Rochester) (DAB/NIA) |
11: |
25 am - |
11: |
45 am | Connecting cancer to aging – an evolutionary perspective James V. Degregori (University of Colorado) (DAB/NIA) |
11: |
45 am - |
12: |
Coffee break
10:30 am - 11:50 am
10:30-10:50
10:50-11:1005 pm | Panel Discussion |
12: 05 pm - 12: 25 pm | Lunch |
12: 25 pm - 1:10 pm 12:25 pm-12:45 pm 12: 45 pm -1: 05 pm | Cellular Senescence in Cancer and Aging Moderator: Basil Eldadah, NIA Mechanisms of immunosenescence and Immune response to vaccines in elderly Nan-Ping Weng (Laboratory of Molecular Biology and Immunology, LMBI, NIA-IRP) Cellular senescence in aging and cancer. Darren Backer (Majo Clinic) |
11:10-11:30
The differences in response to CART-T cell therapy in young versus old persons Carl June (University of Pennsylvania)
11:30 am - 11:50 am
Panel Discussion
11:50 pm - 12:50 pm
Lunch
12:50 pm - 1:50 pm
1: 05 pm – 1:25 pm | Panel Discussion |
1:25 pm - 2:10 pm |
| Implication of Oxidative Stress Towards Cancer Biology Moderator: Konstantin Salnikow, DCB/NCI |
12:50-1:10
1: 25 pm - 1: |
45 pm | Gender effects in cancer and aging Vadim Gladyshev (Brigham and Women’s Hospital, Harvard Medical School) |
1: |
45 pm – 2:05 pm | Dysregulation of iron metabolism in cancer and aging Suzy Torti (University of Connecticut) |
2:05 pm - 2:25 pm | Panel Discussion |
2: 25pm - 2: |
30 pm
| Coffee break |
2:30 pm – 3:10 pm |
Senescence, Immune Response and Cancer in the Elderly |
Moderators: Matt Young and Anil Wali |
, NCI |
2:30-2:50
Metabolites: effects on2:50-3:10
New technologies to study mitochondria-telomere cross-talk
Ben van Houte
3:10-3:30
3:30-3:50
|
|
|
|
3: |
10pm - |
3: |
30 pm | Panel Discussion |
3: |
30 pm |
- 4: |
30 pm |
Coffee Break
4:20 pm - 5:20 pm
3:40-4:00 Pm
3: 30- 3:50 Pm 3:50- 4:10pm |
Environmental Factors: the Overlap of Carcinogens/Gerontogens Moderator: |
Les Reinlib NIEHS Environmental genomics of breast and prostate cancer Susan Neuhausen (City of Hope) ( NIEHS)
Breast Cancer in young & older women; Lead, Carolina Breast Cancer Study; co-I, African American Breast Cancer Epidemiology and Risk (AMBER); Cancer Genome Atlas Melissa Troester, UNC CH (NIEHS) |
4:20-4:50
Exploring Social Networks and Social Capital for Cancer Screening among Minorities in Public Housing Jamilia Sly (Icahn School of Medicine, Mt. Sinai)
4:50 pm - 5:20 pm
Panel Discussion
5:20 pm
Day
1 Wrap-UpDay 2, April 3October 27, 2020
7:30-8:00am
Registration
10:00 am - |
10: 10 am | Goals and Objectives |
Konstantin Salnikow
10:10 am - |
10: |
40 am | Keynote: Epigenetic linkage of aging, cancer and nutrition Trygve Tollefsbol |
(University of Alabama |
) (DCP/NCI) |
10:40 am - |
8:50-9:10
Simmin Meydani D.V.M., Ph.D. Tufts University, MA
Potential Impact of bioactive food components on cancer in the aged
9:10-9:30
11:50 am | Potential Impact of Nutrition on Cancer Prevention Moderator : |
Gabriela Riscuta and Pat Prasana | |
10:40 am -11:00 am
| Senolytic bioactive food components and their biological pathway for action Simmin Meydani (Tufts University) (DCP/NCI)
|
11:00-11:20 am | Cancer prevention in elderly and particularities for mechanisms of action Chengguo Xing (University of Florida) (DCP/NCI) |
11:20 am - 11:50 am |
The mechanisms of fasting and advanced glycation end products in cancer prevention in elderly Sebastian Brandhorst |
(UCLA) (DCP/NCI) |
11:50 am -12:10 |
9:30-9:50
Cancer prevention in elderly and particularities for mechanisms of action Chengguo Xing Ph.D., University of Florida
am | Panel Discussion |
12:10 |
- |
12: |
Coffee Break
30 pm | Lunch Break |
12 |
:30 pm - |
1:00 pm | Keynote speaker: Jan Van Duersen (Mayo Clinic) |
1:00 |
pm - |
2:00 |
pm | Cancer Therapeutics and Treatment Optimization for the Elderly Moderators: Weiwei Chen and Christina Liu |
1:00 pm- |
1:20 pm
| Improvement of cancer therapy by exploiting cellular senescence Judith Campisi (Buck Institute for Research on Aging) (DCTD/NCI) |
1:20 pm - |
1:40 |
pm | The development of AI-enhanced cardiac MRI to address cardiotoxicity in elderly Multiple Myeloma patients Greg Lanza (Washington University at St. Louis) ( NCI/DCTD |
) |
1:40 pm - |
2:00 pm | Treatment Optimization |
for the |
elderly with comorbidities |
Heidi Klepin |
(Wake Forest) (NCI/DCTD |
) |
2:00 |
pm - |
2: |
20 pm | Panel Discussion |
2: |
20- |
2: |
30 pm | Wrap Up and Adjourn |
Planning Committee
Luigi Ferrucci (NIA) Chair
Gabriela Riscuta (NCI/DCP); co-chair
Konstantin Salnikow (NCI/DCB); co-chair
Nelson Aguila (NIH/NCI)
Weiwei Chen (NIH/NCI)
Basil Eldadah ( NIA)
Max Guo (NIH/NIA/ERP)
Christina Liu (NIH/NCI)
Pat Prasana ( NIH/NCI/DCTD)
Leslie Reinlib (NIH/NIEHS)
Sudhir Srivastava (NIH/NCI/DCP)
Anil Wali (NIH/NCI)
Matthew Young (NIH/NCI/DCP)
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