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The initiatives proposed below are intended to support production operation of caBIG® semantics while evolution toward a national-scale capability begins.

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Initiative 1. Distributed, federated metadata repositories and model repositories and operations
Initiative 2. Automated generation of metadata from line-of-business artifacts
Initiative 3. Rules management and contracts support (behavioral semantics)
Initiative 4. Semantics support for W3C service oriented architecture resources
Initiative 5. HL7 CTS II/ OMG MIF compliant federated terminology services
Initiative 6. Controlled biomedical terminology, ontology and metadata content
Initiative 7. Assessment of semantic unification of compositional and derivational models

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