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This chapter introduces general caIntegrator procedures and how to obtain help to use caIntegrator.

Topics in this chapter include:

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About caIntegrator

NCI Center for Biomedical Informatics and Information Technology (CBIIT) is developing a novel translational informatics platform called caIntegrator that allows researchers and bioinformaticians to access and analyze subject annotation and experimental data across multiple subject annotation trials and studies. The caIntegrator framework provides a mechanism for integrating and aggregating biomedical research data and provides access to a variety of data types (for example, immunohistochemistry (IHC), microarray-based gene expression, SNPs, subject annotation trials data, imaging data, etc.) in a cohesive fashion.

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  1. Go to the CBIIT caIntegrator login page or use the URL provided by your System Administrator for the caIntegrator instance at your institution.
  2. Click the Register Now hypertext link, under the caIntegrator login section in the lower center of the page. This opens the account registration form.
  3. Enter the appropriate information. Fields with an asterisk are required.

    Security Information

    Entry

    Do you have an LDAP account?

    An LDAP account is a user profile you may have with your institution or CBIIT. If you answer Yes, enter your username and password. This allows caIntegrator to verify that your credentials are correct.

    If caIntegrator does not validate your LDAP profile, you are asked to reenter your credentials. You can choose to answer No. In this case, the System Administrator will manually ensure that you do not get a duplicate LDAP account during provisioning. You can then cancel the action or talk with your System Administrator about the problem.

    If you select No (you do not have an LDAP account), the text boxes for entering the LDAP account information disappear. You must indicate the role you would like to be assigned in caIntegrator, and continue entering the appropriate information in the Account Details section.

    Info
    titleNot logged in?

    After you submit your registration request, you can continue to use caIntegrator without an account to browse and search available data while your account is verified and activated.

    Username

    Enter your LDAP user name.

    LDAP Password

    Enter your password. Your password is case-sensitive.

    Anchor
    caIntegratorRoles
    caIntegratorRoles
    Requested role(s)

    Select one or more of the roles, described in this table:

    Include Page
    caIntegrator roles
    caIntegrator roles
    .

  4. Enter your account details. Field names followed by asterisks are required.
  5. Click Submit Registration Request. Click Cancel to terminate the registration. A Registration Request confirmation page appears if you submit the request.

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  1. The caIntegrator system administrator receives an email containing all of the information you specified in the new user request form.
  2. An account request confirmation email is also sent to you, the prospective user, at your specified email address.
  3. The system administrator creates your user account and sends you an email verification.
  4. You can log in to caIntegrator.

    Info
    titleWhile your account is activated

    Once you register, you can continue to use caIntegrator without an account to browse and search publicly available data and download data while your account is being activated.

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Sidebar Option

Function

[Study Name]

When you log in, one study displays in the left sidebar by default. Any study that you select in the My Studies drop-down list in the upper right of the page replaces this default selection.

Home

Click this to return to the home page for the selected study.

Search [Study Name]

Click this option to open the Search [Study Name] page from which you can launch queries into your selected study. For more information, see 4 - Searching a caIntegrator Study.

Study Data

Click Saved Queries > My Queries to open the list of previous queries you saved. Click any item in the list to open the saved query, which displays on the Criteria, Columns and Sorting tabs. From those tabs, you can modify criteria and/or launch the query again. For more information, see Saving a Query.
Click Saved Lists > Global Lists or > My Lists to open gene lists that have been saved for a study. From any page in caIntegrator that shows such a group, you can save a such a list of genes to be used for searches or analyses. See Creating a Gene or Subject List.
Click Saved Copy Number Analysis to open an Edit GISTIC Analysis page. You can review genes retrieved from the analysis or, with appropriate permissions, you can edit the metadata for the analysis. See Editing a GISTICAnalysis.

Analysis Tools

Click any of the listed options to open a page where you can launch an analysis of the data in the selected study.

Study Management

Click either of the listed options to manage the selected study through editing or deleting it or by creating a new study.

Application Management

Click Manage Platforms to identify, add or remove platforms that caIntegrator supports. For more information, see Managing Platforms.

caIntegrator Menu

  • Click Support to view contact information for Application Support.
  • Click User Guide to open the caIntegrator User's Guide.

Help

Click the Help icon at the top of each page to open a context-sensitive topic. The help page displays information (from this user's guide) that corresponds to the page from which help was opened.

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  • Because in looking at the study, you may not know the meaning of all the annotations, you can open a reference page with a summary of the annotations. Click the Data Dictionary: View link on the study home page, as described in the following section.
  • From the study summary page, you can also open a log for the study. Click the Study Log: View link on the page to see all log entries with descriptions. See #Study Study Log for more information.

Data Dictionary

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Help and additional resource links remain fixed through all the user interface pages.

Application Support

For any general information about the application, application support or to report a bug, contact NCICB Application Support.

Email:

When submitting support requests via email, please include:

  • Your contact information, including your telephone number.
  • The name of the application/tool you are using
  • The URL if it is a Web-based application
  • A description of the problem and steps to recreate it.
  • The text of any error messages you have received

Application Support URL

http://ncicb.nci.nih.gov/NCICB/support

Telephone: 301-451-4384Toll free: 888-478-4423

Telephone support is available:
Monday to Friday, 8 am – 8 pm Eastern Time,
excluding government holidays.

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