With the phasing out of the caBIG program, the name of the caDSR “caBIG” Context is being changed to “NCIP” (National Cancer Informatics Program). This is a NAME change only; all existing content associated with “caBIG” will show “NCIP” as the context name instead. The release of Form Builder 4.1 will mark the date that this change is visible in the caDSR Tools.
Refer to the caDSR Contexts FAQs for information about the impact of this change. Contact Denise Warzel with any issues not noted here and concerning any issue that will have a negative impact on your organization or use of caDSR.
Metadata Needs and Support
The caDSR (Cancer Data Standards Registry and Repository) is a metadata repository based on the ISO/IEC 11179 Metadata Registry standard. It supports a broad community of users both inside and outside of NCI that have requirements to ensure the longevity and consistency of biomedical research data by registering metadata standards in caDSR.
What is a metadata standard? A metadata standard is a high level document which establishes a common way of structuring and understanding data, and includes principles and implementation issues for utilizing the standard. There are many metadata standards purposed for specific disciplines.
. Content owners and end users have included include NCI and its partners in clinical trials, academic institutions (including NCI Designated Cancer Centers, SPOREs and NCTN/ETCTN), other NIH institutes (including NICHD, NHLBI, NCATS and NIDCR), other federal agencies (in particular the FDA), pharmaceutical companies, standards development organizations (e.g. CDISC) and a range of international biomedical organizations. For more information see the caDSR Collaborations and Use.
Requirements from researchers and/or their supporting informatics groups drive the creation of metadata in the caDSR. Metadata content development usually starts with a request for assistance by a researcher planning clinical or research data collection. Metadata curators work with the user and EVS to identify appropriate vocabulary while identifying a mix of new and existing CDE content to support the scientific requirement. Curators always attempt to reuse existing metadata (where that content supports the scientific requirement) as a way to help scientists ensure the compatibility of their data with other data collected across the enterprise, and sometimes researchers request that their content be harmonized with specific existing projects.
The word cloud that follows illustrates the broad variety of collections of data elements that are reposited in the caDSR for various communities and types of studies.
CBIIT’s management of metadata began as part of an effort to support CTEP’s reporting for breast cancer trials, and from a need to develop and disseminate standards that would ensure consistency and accuracy in reporting across the NCI Clinical Trial Network (NCTN/ETCTN) and Lead Protocol Organizations (LPOs). This led to the establishment of a centralized resource and associated web-based tools for creating, clearly documenting, and sharing human- and machine-readable data descriptions. The need to maintain and share data about data, or metadata, became the basis for the NCI’s repository of CDEs, metadata, and data standards, what is now known as the caDSR. A CDE Steering Committee was formed to define what kind of metadata was needed for the repository. Driven by the needs from community to create, share, and manage CDEs over time, a set of metadata attributes was established, which included attributes such as human friendly name(s), text definition(s), valid values, unique identifiers, and workflow status. Consultation with appropriate experts identified ISO 11179, an international standard for metadata registries, as meeting the needs identified by the CDE Steering committee. As time went on, more groups wanted to record their data elements and share them via the caDSR, so additional features were added, including extensions of ISO 11179 to enable storage of metadata describing Case Report Forms (CRFs) that use CDE metadata as the basis for questions on the CRFs.
A note on the term “Common Data Element” (CDE). While originally intended to mean a data element that was reused across groups, the term has come to mean any description of a variable and its valid values. In this document, we will use the standard NCI version of this definition, which is to say a variable description (including valid values) described in the caDSR using its implementation of the ISO 11179 variable, regardless of whether the element in question has been used more than once.
This Wiki Space
This is the wiki home page for the caDSR wiki space. You may edit pages if you are working on them with the authors. You are welcome to leave comments. This wiki space includes the following .
- caDSR Content
Focuses on the Metadata Content within the caDSR and is most useful for consumers. The pages include Data Standards, Harmonization, Reuse and Business Rules that establish the capabilities of the caDSR Tools.
- caDSR Database and Tools
Provides access to caDSR tools and links to the tool summary page for current user documentation and technical information like release notes.
caDSR Future Requirements
We continually look at new requirements and have an initiative begun in 2014 to replace the aging software and infrastructure currently supporting caDSR end users. This is an opportunity to link our efforts more broadly with NIH wide CDE and metadata initiatives. Please see the caDSR Requirements pages for more information.
For a complete list of current caDSR Tool user documentation, application guides, release notes, and FAQs, see the caDSR Documentation wiki page.
Email address or URL
|caDSR End User Discussions forum|
caDSR End User Discussions forum
For end user issues regarding the caDSR tools and content
For developer issues regarding the caDSR APIs and use of caDSR Metadata
Archive for content users such as Curators
Archive for developers using caDSR Metadata, such as UML Model owners (subscription required)
---No email address
Index of all NIH mail lists
NCICB NCI Application Support
How to Cite caDSR
To cite the NCI Semantic Infrastructure, use the following reference.
Komatsoulis, G.A., Warzel, D.B., Hartel, F.W., Shanbhag, K, Chilukuri, R, Fragoso, G., de Coronado, S, Reeves, D.M., Hadfield, J.B., Ludet, C., and P.A. Covitz (2007) "caCORE version 3: Implementation of a model driven, service-oriented architecture for semantic interoperability." Journal of Biomed Informatics. 2008 February; 41(1): 106--123. Published online 2007 April 2. doi: 10.1016/j.jbi.2007.03.009.
To cite the caDSR Form Builder OneData general software, use the following reference.
NCI caDSR Form BuilderOneData. <https://formbuildercadsr.nci.nihcancer.gov/FormBuilderonedata/formSearchActionHome.dojsp> National Cancer Institute, Center for Biomedical Informatics and Information Technology, 01 Oct. 2010. Web. 17 Jan. 2013.
To cite a specific collection of forms in caDSR, or to cite caDSR CDEs in a particular collection or group, use a reference like the following.
"[Protocol or Classification Scheme Name]." [Context name], [Node name], NCI caDSR Form BuilderOneData. <https://formbuildercadsr.nci.nih.govcancer.gov/onedata/Home.jsp> National Cancer Institute, Center for Biomedical Informatics and Information Technology, 01 Oct. 2010. Web. 17 Jan. 2013.
Example: " CALGB: 10603 Treatment Form ." CTEP, Protocol Forms, NCI caDSR Form BuilderOneData. <https://formbuildercadsr.ncicancer.nih.gov> National Cancer Institute, Center for Biomedical Informatics and Information Technology, 01 Oct. 2010. Web. 17 Jan. 2013
To cite caDSR CDE Browser software, use a reference like the following.
To cite caDSR CDEs in a particular collection or group, use a reference like the following.
"[Classification Scheme Name]." [Context name], [Node name], NCI caDSR CDE Browser. <https://cdebrowser.nci.nih.gov> National Cancer Institute, Center for Biomedical Informatics and Information Technology, 01 Oct. 2010. Web. 17 Jan. 2013.
Example: "NAACCR 11.1." PS & CC (NCI Population Sciences & Cancer Control), Classifications, Division of Population Cancer Control and Population Sciences, NCI caDSR CDE BrowserOneData. <https://cdebrowsercadsr.nci.nih.govcancer.gov/onedata/Home.jsp> National Cancer Institute, Center for Biomedical Informatics and Information Technology, 01 Oct. 2010. Web. 17 Jan. 2013 .