Summary

On presenting the

Summary

In 2004 when presenting the NCI Executive Committee the ACRIN proposal to conduct the CTC trial to the NCI Executive Committee, a case was made that publicly accessible image data sharing , publicly accessible through an as yet to be developed NCI Image Archive (NCIA) would offer a valuable would be an invaluable research asset to a wide the image processing research community. Adding to the many merits of that proposal, the data-sharing component was strongly endorsed. ACRIN completed the trial expeditiously and its results were published in NEJM in fall 2008 to wide interest . Please see their NEJM publication for their published results and the ACRIN website itself for (N Engl J Med. 2008 Sep 18;359(12):1207-17). The ACRIN website has a more complete protocol description (http://www.acrin.org/TabID/151/Default.aspx). ACRIN has graciously allowed the permitted a wider research community access to a portion of the data from that trial.

Thus NCIA has made accessible a limited portion of DICOM image cases for download, de-identified of private health information, with spreadsheets identifying positive and negative polyp cases. The collection is offered to enlarge the broader research community's ability to develop CAD algorithms for polyp detection. CTC strengthened by competitive CAD methods stands to offer a more efficient public health tool for reducing the incidence of colon cancer.

The several documents found in the "Attachment" tab on this page provide users of the NCIA CT Colonography collection a list of polyp positive cases by size, a key to the findings and an explanation of how to locate cases by NCIA study number that satisfy your interests.

Accrual Details

Submission Client - Field Center & Clinical Trial Processor (CTP)
Collection Security - Publicly available to all registered users
Submission status -
Modality types - CT
Accrual Sites -

The "CT Colonography" (CTC) image collection in DICOM format, PHI de-identified for public download contains 825 cases from optical colonoscopy (OC)-validated subjects who had same-day sequential CTC followed by OC. The attached documents separately lists OC verified cases that contain: 243 Cases where no polyp was found; 69 cases possessing 6 to 9 mm polyps; and 35 cases that possess at least one polyp "larger than 10 mm." The key to the lesion coding in those XL files is: CTC key to XL colon lesion spreadsheet.docx

Data Access

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