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In 2004 when presenting the NCI Executive Committee the ACRIN proposal to conduct the CTC trial to the NCI Executive Committee, a case was made that image data sharing, publicly accessible through an as yet to be developed NCI Image Archive (NCIA) would offer be a valuable research asset to a wide image processing research community. Adding to the many merits of that proposal, the data-sharing component was strongly endorsed. ACRIN completed the trial expeditiously and its results were published in NEJM in fall 2008 to wide interest. Please see their NEJM publication for their published results and the ACRIN website itself for a more complete protocol description (http://www.acrin.org/TabID/151/Default.aspx). ACRIN has graciously allowed the wider research community access to a portion of the data from that trial.

Thus NCIA has made accessible offers a limited portion set (827) of DICOM image cases for download, de-identified of private health information, with spreadsheets identifying positive and negative polyp cases. The collection is offered to enlarge provide the broader broad research community 's an ability to develop CAD algorithms for polyp detection. CTC strengthened by competitive CAD methods stands to offer a more an efficient public health tool for reducing the incidence of colon cancer.

The several documents found in the "Attachment" tab on this page provide users of the NCIA CT Colonography collection a list of polyp positive cases by size, a key to the findings and an explanation of how to locate cases by NCIA study number that satisfy your interestspresent "CT Colonography" (CTC) image collection, publicly downloadable in DICOM format at https://imaging.nci.nih.gov/ncia/  contains 827 cases from the well conducted, optical colonoscopy (OC) validated, ACRIN clinical trial whose subjects underwent same-day sequential CTC followed by OC. The attached documents in this Wiki offer separate lists of those OC verified cases that contain: 243 'no polyp found'; 69 cases possessing 6 to 9 mm polyps; and 35 cases that possess at least one polyp "larger than 10 mm."
Notably, this collection, though  a subset of the ACRIN 2600+ total cases, nonetheless proportionally represents the incidence and prevalence of polyp found in the general population.

Accrual Details

Submission Client - Field Center & Clinical Trial Processor (CTP)
Collection Security - Publicly available to all registered users
Submission status -
Modality types - CT
Accrual Sites -

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