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To enter general information about a sample:

1. Click the Samples caNanoLab menu option. On the Manage Samples Home page, click the Submit a New Sample link. This opens the Submit a New Sample form.

   Info
   title Tip
   Some fields may contain the [Other] option. Click Other to enter an alternative to the selections listed. At that point, your entry is enclosed in [new entry] brackets, indicating that your entry is temporary. Once you click Submit (or Update), your entry is persisted and the brackets disappear.

2. The following table lists and describes the fields on the Submit Sample page. Select or enter the appropriate information. Asterisks indicate required fields.

   Name	Definition
   Sample Name*	Enter a sample name of your choice.
   Point of Contact*	The Point of Contact Add button is not available unless you entered a Sample Name. To add a point of contact, click Add. The Point of Contact Information dialog box opens. Select an Organization Name from the drop-down or select Other and add one. Select a Role in the same manner. Fill in the address, name, phone number, and email. Click Cancel or click Save to return and the POC is added. To edit a point of contact, click Edit next to the POC, update the information, and click Save.

   To clear the entries and start again, click Reset.

3. When you finish defining the sample, click Submit. A message appears verifying the submission.

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To copy an existing sample:

1. Click the Samples menu option. On the Manage Samples home page, click the Copy an Existing Sample link.
2. In the Copy Sample page, enter the name (complete for an exact search or partial to search for sample names that contain the entered text) of the sample to be copied. Both fields on this page are required.
   
   • Click the Search icon ( ) to search the caNanoLab database for the sample. If you entered partial text, you must complete this search before you can execute the copy request. Select from the search results the sample you want to copy.
   • If you skip the Search icon (having entered exact text), the system searches the database anyway for the sample whose name you entered.
3. Enter a name for the copied sample and click Submit. Click Reset to clear all fields and begin again.

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To generate or review a data availability metrics:

1. Perform a search for an existing sample that you submitted. If you are a curator, you needn't have submitted the sample to generate the metrics. See Searching Existing Samples.

2. If data availability has already been generated for a sample, you will see its matmetricsrix summary in the Data Availability column of the Search Results list. Click the link for the availability results in the column to view them in their entirety.

   Info
   If you open the data availability metrics in this manner, you can only review the metrics. To edit it, proceed with step 3.

   If you open the data availability metrics in this manner, you can only review the metrics. To edit it, proceed with step 3.

3. To generate an editable availability metrics for a sample, on the search results page, click Edit corresponding to the sample.
4. At the bottom of the sample details page that opens, click Generate corresponding to Data Availability Metrics.
5. The metrics table displays high-level medidata for minimal care. Three columns are shown:
   
   • caNanoLab – Lists all data elements that can be added to the sample in caNanoLab.
   • MinChar – Lists the minimum nanoparticle characterization standards as established by MinChar Initiatives

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     .
   • [Name of sample] – Check marks indicate the data element annotations added to the sample.
6. The top of the table displays two percentages based on the total and actual number of attributes available for the sample:
   • The total possible number of caNanoLab characteristics is 30. The sample may have 23 out of 30 filled in. A percentage is calculated from 23 out of 30.
   • The total possible number of MinChar characteristics is 9. The sample may have 4 out of 9 filled in. A percentage is calculated from 4 out of 9.
   Click Delete to delete the metrics for this sample.
   Click Cancel to close the data availability section of the Update Sample page.
7. Click Update to regenerate the metrics.

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Accessing Sample Search Options

To begin a basic or advanced search, you have several paths to access those options:

1. To continue with a basic search, see Launching a Basic Search.
2. To launch an advanced search, see Launching an Advanced Search.

Launching a Basic Search

To launch a basic search for a sample

1. There are three ways to access the basic sample search: From the home page Browse caNanoLab panel, or if you are logged

   From the Public caNanoLab Home page, in the Browse caNanoLab panel, click Search Samples;
   – OR –
   After logging

   in, click the Workflow menu option and

   click

   Search Samples

   ;
   – OR –
   After logging in, click the Samples menu option.
   The Manage Samples page opens.
2. To continue with a basic search, see Launching a Basic Search.
3. To launch an advanced search, see Launching an Advanced Search.

Launching a Basic Search

To launch a basic search for a sample

1. icon, or just click the Samples menu option.
   The Manage Samples page displays.

2. Click Search Existing Samples in the Sample Links panel

3. Display the Manage Samples page.

4. Click the Search Existing Samples on the Manage Samples page.

   The following table lists and describes each field. Enter text or select options as appropriate.

   Info
   title "Other" option
   Some fields may contain the [Other] option. Click Other to enter an alternative to the selections listed. At that point, your entry is enclosed in [new entry] brackets, indicating that your entry is temporary. Once you click Submit (or Update), your entry is persisted and the brackets disappear.

   When defining search criteria, there are no "required" fields. You can add only those parameters that you consider essential to the search.

   Sample Search Options	Description
   Keywords	Enter one or more keywords by which samples could be identified in this search. caNanoLab can search for characterization or publication keywords, as well as text describing characterizations.
   Sample Name	Enter text for the name of a sample. Select Contains (for search using partial text) or Equals (for exact text search).
   Sample Point of Contact	Enter text for the name or organization point of contact. Select Contains (for search using partial text) or Equals (for exact text search).
   Composition	Nanomaterial Entity Select from the scroll list the nanoparticle category to which the nanomaterial entity targeted by the search belongs. Example: Dendrimer Functionalizing Entity Select from the scroll list the functionalizing category to which the sample targeted by the search belongs.* Monomer Polymer Quantum Dot Antibody Biopolymer Small Molecule Function Select from the drop-down list the function type category which best fits the sample targeted by the search: Imaging Function [Other] Targeting Function Therapeutic Function Transfection *You may see terms in caNanoLab that are not defined in the help glossary. These have been added by curators as [other]; they may be reviewed and defined at a later time.
   Characterization Type/Characterization	Click from the drop-down list on the left, the characterization type that applies to the sample to be searched: Physico-Chemical, In Vitro or In Vivo. Your selection determines the sub-categories that display in the Characterization field to the right. Select one or more of the items in the Characterization list.* (CTRL + click to select more than one.) Physico-Chemical Characterizations: Molecular Weight Physical State Purity Relaxivity Shape Size Solubility Surface In Vitro Characterizations:   Blood Contact Cytotoxicity Enzyme Induction Immune Cell Function Oxidative Stress Sterility  Targeting Transfection In Vivo Characterizations: Pharmacokinetics Toxicology *You may see terms in caNanoLab that are not defined in the help glossary. These have been added by curators as [other]; they may be reviewed and defined at a later time.

5. To execute the search, click the Search button.

   Info
   title No parameters?
   Include Page No parameter search No parameter search

   
   To clear all fields and start again, click the Reset button.

   For information about the search results, see Sample Search Results.

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To launch an advanced search of the samples in the caNanoLab database

1. There are two ways to access the advanced sample search:

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1. Display the Click the Workflow menu option and Search Samples icon, or just click the Samples menu option
   The Manage Samples page displays.

2. Click Advanced Sample Search on the Manage Samples page in the Sample Links panel.

   The following table lists and describes each field. Enter text or select options as appropriate.

   Advanced Search Category	Description
   Sample Criteria	Select an option in the first drop-down list. Select from the second drop-down, Contains (for search using partial text) or Equals (for exact text search). Enter complete or partial text in the text box.
   Composition Criteria	Select an option in the first drop-down list. Your selection drives the options that display in the second drop-down as well as the options or text box that displays for the rest of the category. Select from the second drop-down, Contains (for partial text search) or Equals (for exact text search). Select your options or enter appropriate text in the text box. Note: Chemical name is optional. Available terms are defined in the caNanoLab Glossary.
   Characterization Criteria	Select a Characterization Type in the first drop-down list. Your selection drives the options that display in the second drop-down as well as the options or text boxes that displays for the rest of the category. The last text box is either a boolean value or number value, depending on the third drop-down list. An optional drop-down box for units displays only if the data has a unit. Select your options or enter appropriate text in the text box(es). Available terms are defined in the caNanoLab Glossary.

3. Click Add to each set of criteria you define. As you add criteria, they display in a table above the criteria fields on the page. Click Reset to clear the fields.
4. Select the And or Or operand at the bottom of each set of criteria when you enter more than one criteria in a set. And or Or determines whether, for the set, the search finds samples that meet all of the criteria or that meet any one of the criteria.
5. Select the And or Or operand at the bottom of the page that determines whether the search finds samples that meet only all of the criteria or that meet any one of the criteria.
6. To execute the search, click the Search button.
   To clear all fields and start again, click the Reset button.

   For information about the search results, see Sample Search Results.

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