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	Understanding the Navigation Tree
	Understanding the Navigation Tree

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Characterization
Characterization
[Sample] Characterization Overview

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Info
You may have the option to add or delete function details with Add and Delete buttons. If you do not have certain security privileges, the Add and Delete buttons are hidden, and you have read-only access to the existing items.

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Submitting Characterizations

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Adding a Physico-Chemical Characterization

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The Characterization type is already selected as Physico-Chemical Characterization. In the Characterization Name field in the upper right, select from the drop-down list the name of the Characterization you want to add.
For more information, see Defining Physico-Chemical Characterization.
The [Characterization] Properties section displays only for Physical State, Shape and Solubility characterizations. Define properties for the characterization, if applicable. For specific information, see Defining Physico-Chemical [Characterization] Properties .
In the Design and Methods section, complete the fields describing techniques and instruments used to derive the data. For more information, see Defining Physico-Chemical Design and Methods.
In the Finding section, add data findings and supporting documentation relating to the sample. For more information, see Describing Findings for Physico-Chemical Characterization .
In the Analysis and Conclusion section, enter any relevant analyses and conclusions reached by the data.
In the Copy to Other Samples... section, select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact. For more information, see Copying Characterizations.
When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.

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Defining Physico-Chemical Characterization

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After defining the [characterization] properties, continue the process described in Adding a Physico-Chemical Characterization.

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Defining Physico-Chemical Design and Methods

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Continue the process described in Adding a Physico-Chemical Characterization.

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Describing Findings for Physico-Chemical Characterization

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Click Add to expand the section, then complete the instructions as described in Adding Data and Conditions and Adding a File.

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Adding Data and Conditions

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After adding data and conditions to the sample, continue the process described in Adding a Physico-Chemical Characterization.

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Adding a File

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	Adding a file
	Adding a file

After adding one or more files, continue by Adding Data and Conditions or if you have no derived data to add, return to the steps described in Adding a Physico-Chemical Characterization.

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Adding an In Vitro Characterization

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The Characterization type is already selected as In Vitro Characterization. In the Characterization Name* field in the upper right, select from the drop-down list the name of the Characterization you want to add (required).
For more information, see Defining an In Vitro Characterization.
The [Characterization] Properties section displays only for Cytotoxicity, Enzyme Induction and Transfectionin vitro characterizations. Define properties for the characterization, if applicable. For specific information, see Defining In Vitro Characterization Properties.
In the Design and Methods section, complete the fields describing techniques and instruments used to derive the data. For more information, see Defining In Vitro Design and Methods.
In the Finding section, add data findings and supporting documentation relating to the sample. For more information, see Describing Findings for an In Vitro Characterization.
In the Analysis and Conclusions section, enter any relevant analyses and conclusions reached by the data.
In the Copy to Other Samples... section, select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact. For more information, see Copying Characterizations.
When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.

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Defining an In Vitro Characterization

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After defining the summary, continue the process described in Adding an In Vitro Characterization.

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Assay Type Options for In Vitro Characterizations

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Characterization Selection	Assay Type Corresponding to Characterization
Blood Contact	Coagulation Complement Activation Hemolysis Plasma Protein Binding Platelet Aggregation
Cytotoxicity	Caspase 3 apoptosis Cell viability Gene expression Mitochondrial function Mitochondrial membrane potential Proliferation
Immune Cell Function	CFU – GM Chemotaxis Cytokine induction Cytotoxic activity Leukocyte proliferation Oxidative Burst Phagocytosis
Oxidative stress	GSH homeostasis Lipid peroxidation ROS generation
Sterility	Bacterial/yeast/mold Endotoxin Mycoplasma
Targeting	Cell binding/Internalization
Transfection	Click [Other] to add an assay type.

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Defining In Vitro [Characterization] Properties

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After defining the [characterization] properties, continue the process described in Adding an In Vitro Characterization.

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Defining In Vitro Design and Methods

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Continue the process described in Adding an In Vitro Characterization.

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Describing Findings for an In Vitro Characterization

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Click Add to expand the section, then complete the instructions as described in Adding Data and Conditions and Adding a File.

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Adding Data and Conditions

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After adding data and conditions to the sample, continue the process described in Adding an In Vitro Characterization.

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Adding a File

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	Adding a file
	Adding a file

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Adding an In Vivo Characterization

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The Characterization type is already selected as In Vivo Characterization. In the Characterization Name field in the upper right, select from the drop-down list the name of the Characterization you want to add. The options for In Vivo Characterization are Pharmacokinetics and Toxicology. There are no customizations on this Characterization page based on either of these selections.
For more information about completing the Summary section, see Defining an In Vivo Characterization Summary.
No [Characterization] Properties section displays for in vivo characterizations.
In the Design and Methods section, complete the fields describing techniques and instruments used to derive the data. For more information, see Defining In Vivo Design and Methods.
In the Finding section, add data findings and supporting documentation relating to the sample. For more information, see Describing Findings for In Vivo Characterizations.
In the Analysis and Conclusion section, enter any relevant analyses and conclusions reached by the data.
In the Copy to Other Samples... section, select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact. For more information, see Copying Characterizations.
When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.

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Defining an In Vivo Characterization Summary

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After defining the summary, continue the process described in Adding an In Vivo Characterization.

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Defining In Vivo Design and Methods

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Continue the process described in Adding an In Vivo Characterization.

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Describing Findings for In Vivo Characterizations

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Complete the instructions as described in Adding Data and Conditions and Adding a File.

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Adding Data and Conditions

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	Data and conditions2
	Data and conditions2

After adding data and conditions to the sample, continue the process described in .Return to top of page

Adding a File

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	Adding a file
	Adding a file

After adding one or more files, continue by Adding Data and Conditions or if you have no derived data to add, return to the steps described in Adding an In Vivo Characterization.

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Viewing Characterizations Summary

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title	Read only permissions?

If you have read only permissions, you will be able to view characterization but not perform associated tasks

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Characterization Tasks

From a characterization summary page, and with curator privileges, you can perform these tasks:

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