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AccessCharacterization AccessCharacterization

Accessing a Sample Characterization

To access characterization functions in the Navigation Tree

1. Perform a search for the sample.
2. Click the Characterization button Edit in the search results row.
3. In the Navigation Tree on the left sidebar, click the Characterizations link. 

4. The All tab displays characterizations already added to the sample. The remaining tabs show annotations specific to those categories.

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   Based on your security privileges, you may have read-only access to existing items or the ability to Add and Delete function details.

   

5. On the All tab, with the appropriate security privileges, click Add next to the category of characterization annotations you want to add, such as Physico-chemical Characterization. You can also select the corresponding tab where you can add characterizations to the sample.

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The page that opens after you click an Add button to add on a characterization tab is very similar for all characterization types. The page differs only in the Properties section if there are special properties driven by the selection of characterization names. They also differ in the drop-down values for the column name in the Finding section driven by the characterization name and assay type selections.

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The following is a general path to add a physico-chemical characterization. Links are provided todetailed to detailed instructions.

1. Access the characterization functions.

2. Click the All or Physico-Chemical Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization Type* field.

   Field/Section	What to Do
   Characterization Type	Already selected as Physico-Chemical Characterization.
   Characterization Name*	Select from the drop-down list the name of the Characterization you want to add (required).
   [Characterization] Properties	Displays only for Physical State, Shape and Solubility characterizations. Define properties for the characterization, if applicable.
   Design and Methods	Complete the fields describing techniques and instruments used to derive the data.
   Finding	Add data findings and supporting documentation relating to the sample.
   Analysis and Conclusions	Enter any relevant analyses and conclusions reached by the data.
   Copy to other Samples...	Select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

3. When you finish, click Submit to save the data to the sample.

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1. Access the characterization functions.

2. Click the All or In Vitro Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization* field.

   Characterization Type

   Field/Section	What to Do
   Already selected as In Vitro Characterization
   Characterization Name*	Select from the drop-down list the name of the Characterization you want to add (required).
   Fill in the general information about the characterization.
   [Characterization] Propertieson][Characterization] Properties	Displays only for Cytotoxicity, Enzyme Induction and Transfection in vitro characterizations. Define properties for the characterization, if applicable.
   Design and Methods	Complete the fields describing techniques and instruments used to derive the data.
   Finding	Add data findings and supporting documentation relating to the sample.
   Analysis and Conclusions	Enter any relevant analyses and conclusions reached by the data.
   Copy to Other Samples...	Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

3. When you finish, click Submit to save the data to the sample.

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To continue defining this characterization

1. The Characterization Type is already selected as In Vitro Characterization.
2. For the Characterization Name* select from the drop-down list the name of the Characterization you want to add (required).
3. The Assay Type populates automatically with options that display only for these in vitro characterization selections: Blood Contact, Cytotoxicity, Immune Cell Function, Oxidative Stress, Sterility and Targeting. Select an option, if appropriate, or if there are none or if you prefer, select [Other] to name the assay type.
4. If Protocol Name – Version is available, select from the drop-down list the protocol from which the data is derived. A hyperlink to the protocol text file should appear (if the protocol is not private to the user and the protocol file exists). However, protocol files are not required. Click the hyperlink to open or save the file.
5. A hyperlink to the protocol text file should appear (if the protocol is not private to the user and the protocol file exists - ie. protocol files are not required).
6. Select from the drop-down list or enter the Characterization Source from which the characterization data is derived, such as a vendor or a laboratory (NCL).

7. In Characterization Date, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

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   Include Page Other options Other options

After defining the summary, add an In Vitro Characterization.

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Assay Type Options for In Vitro Characterizations

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• For Cytotoxicity, enter the appropriate Cell Line.
• For Enzyme Induction, enter your name of choice.
• For Transfection, enter the appropriate Cell Line.

After defining the [characterization] properties, add an In Vitro Characterization.

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Defining In Vitro Design and Methods

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Once you enter the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Continue to adding an In Vitro Characterization.

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Describing Findings for an In Vitro Characterization

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1. Access the characterization functions.

2. Click the All or In Vivo Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization* field.

   Field/Section	What to Do
   Characterization Type	Already selected asIn Vivo Characterization	Fill in the general information about the characterization.
   Characterization Name*	Select from the drop-down list the name of the Characterization you want to ad (required). The options for In Vivo Characterization are Pharmacokinetics and Toxicology. There are no customizations on this Characterization page based on either of these selections. For more information about completing the Summary section, see Defining an In Vivo Characterization Summary.
   [Characterization] Properties	Displays for in vivo characterizations.
   [Characterization] Properties	Displays for in vivo characterizations.
   Design and Methods	Complete the fields	Design and Methods	complete the fields describing techniques and instruments used to derive the data.
   Findings	add Add data findings and supporting documentation relating to the sample.
   Analysis and Conclusions	Enter any relevant analyses and conclusions reached by the data.
   Copy to Other Samples...	Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

3. When you finish, click Submit to save the data to the sample.

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Defining an In Vivo Characterization Summary

To continue defining Summary fields

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Defining an In Vivo Characterization

To define general information about the characterization

1. The Characterization Type is already selected.
2. For the Characterization Name*, select from the drop-down list the name of the Characterization you want to ad (required). The options for In Vivo Characterization are Pharmacokinetics and Toxicology. There are no customizations on this Characterization page based on either of these selections. 

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2. You can leave the Assay Type field blank or specify an Assay Type.

3. If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.

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   Include Page Other options Other options

4. Select from the drop-down list or enter the Characterization Source from which the characterization data is derived, such as a vendor or a laboratory (NCL).

5. In the Characterization Date field, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

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1. : dd/mm/yyyy.

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Defining In Vivo Design and Methods

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Once you specify the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Continue the process described in Adding an In Vivo Characterization.

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Describing Findings for In Vivo Characterizations

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CharacterizationSummary CharacterizationSummary

Viewing Characterizations Summary

Sample characterization, characterizations describing distinctive characteristics or essential features of the sample determined through analytical methods, records record information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by Physico-chemical characterizatics, or by data derived under In vitro and In vivo conditions.

To view a sample characterizations summary

1. Perform a search for the sample.
2. Click Edit in the search results rowOpen the sample of your choice.
3. In the Navigation Tree on the left sidebar, click the Characterizations link. Five tabs showing characterization subcategories display on the page that opens. 
4. The All tab displays characterizations that have already been added to the sample by category with anchor links to each. In addition, the characterization category tabs also display corresponding annotations.

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1. . Additional tabs show annotations added to the sample under their corresponding Physical, In

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See also Characterization Tasks.

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1. Vitro and In Vivo Characterization subcategories.

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Characterization Tasks

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1. Open the sample of your choice.
2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.

3. Click the Print hyperlink at the top right of the page.

   Info
   title Read only access?
   If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Exporting Characterizations

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1. Open the sample of your choice.
2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.

3. Click the Export hyperlink at the top right of the page.

   Info
   title Read only access?
   If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Editing Characterizations

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1. Open the sample of your choice.
2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.

3. Click the Edit hyperlink at the right of the characterization section you want to change. This opens the corresponding Characterization page where you can edit the file by following the same directions as described for creating characterizations.

   Info
   title Read only access?
   If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Copying Characterizations

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1. Open the sample of your choice.
2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
3. On the characterization summary page, click the Edit hyperlink at the right of the section you want to copy. This opens the corresponding Characterization page.
4. At the bottom of the page, in the Copy to other samples... box, select one or more samples that have the same primary point of contact (those listed).
5. Click the Also copy characterization results? box.

6. Click Submit to execute the copy function.

   Info
   title Read only access?
   If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Deleting a Characterization

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1. Open the sample of your choice.
2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
3. Click the Edit hyperlink at the right of the section you want to delete. This opens the corresponding Characterization page.

4. Click the Delete button at the bottom left of the page

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   Info
   title Read only access?
   If buttons described in this section do not display, then you can assume that you have read-only access to the data.

Deleted characterizations are placed in the sample archive for history purposes.

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Publication Tasks Associated with a Sample

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Managing Sample Composition Annotations | caNanoLab User's Guide| Managing Publications in caNanoLab

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