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titleCurator Status

You can perform the procedures described in this section only if you are a curator. If you have read-only permissions, see Viewing a Characterization Summary.

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  1. Perform a search for the sample.
  2. Click Edit in the search results row.
  3. The Navigation Tree appears on the left sidebar and comprises functions which you can use to add annotations to the sample.

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    Understanding the Navigation Tree Abrev
    Understanding the Navigation Tree Abrev

  4. Click the Characterizations link. 
  5. The All tab displays characterizations already added to the sample. The remaining tabs show annotations specific to those categories.

    Sample Characterization tabs with Add Selected on All page

    Info

    If you are a curator, you can review existing characterizations, as well as Add, Edit, Delete, Copy, Print, and Export. If you have read-only access, see see Viewing Characterizations Summary.

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Submitting Characterizations

Once you access Characterizations in the Navigation Tree, you can add different types of information to the sample.

If you have read-only access, you can  View a Characterizations Summary.

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To add a physico-chemical characterization

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Click the All or Physico-Chemical Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization Type* field.

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Add data findings and supporting documentation relating to the sample.

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When you finish, click Submit to save the data to the sample.

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CharacterizationSummary
CharacterizationSummary
Viewing a Characterization Summary

Sample characterizations describing distinctive characteristics or essential features of the sample determined through analytical methods, record information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by Physico-chemical characterizatics, or by data derived under In vitro and In vivo conditions.

To view a sample characterizations summary

  1. Perform a search for the sample.
  2. Click Edit in the search results row.
  3. In the Navigation Tree on the left sidebar, click the Characterizations link. 
  4. The All tab displays characterizations already added to the sampe by category. Additional tabs show annotations added to the sample under their corresponding Physical, In Vitro and In Vivo Characterization subcategories.

    Info
    titleRead only permissions?

    Based on your security permissions, you may have read-only access to characterizations and only be able to see a characterization summary and not be able to perform additional tasks.

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Submitting Characterizations

Once you access Characterizations in the Navigation Tree, you can add different types of information to the sample.

If you have read-only access, you can  View a Characterizations Summary.

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PhysicoChemical
PhysicoChemical
Adding a Physico-Chemical Characterization

To add a physico-chemical characterization

  1. Access the characterization functions.
  2. Click the All or Physico-Chemical Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization Type* field.

  3. Follow these steps to fill in the characterization. Links are provided for additional details.

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    AddPhysicoChemical
    AddPhysicoChemical

    SectionWhat to Do
    Physico-Chemical CharacterizationFill in the general information about the characterization.
    [Characterization] PropertiesDisplays only for Physical State, Shape and Solubility characterizations. Define properties for the characterization, if applicable.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.
    Copy to other Samples...Select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact.
  4. When you finish, click Submit to save the data to the sample.

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Defining the Physico-Chemical Characterization

To define the general information about the characterization

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Other options
Other options

  1. The Characterization Type is already selected as Physico-Chemical Characterization.
  2. For the Characterization Name* select from the drop-down list the name of the Characterization you want to add (required).
  3. The Assay Type field populates automatically with your selection in the Characterization field.
  4. If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.
  5. For Characterization Source, select from the drop-down list or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
  6. In the Characterization Date field, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

Continue to define Physico-Chemical Properties.

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Physico-Chemical Characterization Properties
Physico-Chemical Characterization Properties
Defining Physico-Chemical [Characterization] Properties

The [Characterization] Properties section opens only for the characterizations listed in the table below. The following table lists and describes the Properties fields.

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Other options
Other options

CharacterizationProperty FieldsField Options

Physical State

Type

Select the appropriate type from among the following options:

Shape Properties

Type (required)

Select from the drop-down list the appropriate shape type:

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Defining the Physico-Chemical Characterization

To define the general information about the characterization

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  1. The Characterization Type is already selected as Physico-Chemical Characterization.
  2. For the Characterization Name* select from the drop-down list the name of the Characterization you want to add (required).
  3. The Assay Type field populates automatically with your selection in the Characterization field.
  4. If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.
  5. For Characterization Source, select from the drop-down list or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
  6. In the Characterization Date field, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

Continue to define Physico-Chemical Properties.

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The [Characterization] Properties section opens only for the characterizations listed in the table below. The following table lists and describes the Properties fields.

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CharacterizationProperty FieldsField Options

Physical State

Type

Select the appropriate type from among the following options:

Shape Properties

Type (required)

Select from the drop-down list the appropriate shape type:

Shape Properties

Aspect Ratio

Enter the shape aspect ratio.

Shape Properties

Minimum,/Maximum Dimensions

Enter the minimum and maximum dimensions of the sample, as well as the units of measurement.

Solubility Properties

Solvent

Select from the options or enter the name.

  • alcohol
  • phosphate-buffered saline
  • saline
  • water
 Solubility PropertiesCritical Concentration

Enter appropriate values for the critical concentration, then select the appropriate units for those values.

 Solubility PropertiesIs Soluble?Select Yes or No as to whether the solvent is soluble.

Surface Properties

Is Hydrophobic?

Indicate with Yes or No whether the surface is hydrophobic.

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  1. Access the characterization functions.
  2. Click the All or In Vivo Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization* field.

  3. Follow these steps to fill in the characterization. Links are provided for additional details. AnchorDefining an In Vivo CharacterizationDefining an In Vivo CharacterizationField/SectionWhat to DoIn Vivo CharacterizationFill in the general information about the characterization.
    [Characterization] PropertiesDisplays for in vivo characterizations.Design and MethodsComplete the fields describing techniques and instruments used to derive the data.Findings

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.Copy to Other Samples...

    Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

  4. When you finish, click Submit to save the data to the sample.

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Defining an In Vivo Characterization

To define general information about the characterization

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If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.

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Select from the drop-down list or enter the Characterization Source from which the characterization data is derived, such as a vendor or a laboratory (NCL).

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  1. .
  2. Click the All or In Vivo Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization* field.

  3. Follow these steps to fill in the characterization. Links are provided for additional details.

    Anchor
    Defining an In Vivo Characterization
    Defining an In Vivo Characterization

    Field/SectionWhat to Do
    In Vivo CharacterizationFill in the general information about the characterization.
    [Characterization] PropertiesDisplays for in vivo characterizations.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Findings

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.
    Copy to Other Samples...

    Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

  4. When you finish, click Submit to save the data to the sample.

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Defining an In Vivo Characterization

To define general information about the characterization

  1. The Characterization Type is already selected.
  2. For the Characterization Name*, select from the drop-down list the name of the Characterization you want to ad (required). The options for In Vivo Characterization are Pharmacokinetics and Toxicology. There are no customizations on this Characterization page based on either of these selections. 
  3. You can leave the Assay Type field blank or specify an Assay Type.
  4. If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.

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    Other options
    Other options

  5. Select from the drop-down list or enter the Characterization Source from which the characterization data is derived, such as a vendor or a laboratory (NCL).

  6. In the Characterization Date field, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

Defining In Vivo Design and Methods

Defining In Vivo Design and Methods.

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Defining In Vivo Design and Methods

In the Design and Methods sections, complete the fields as described in the following table.

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Description

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Enter information not covered by other fields on the form.

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Technique and Instrument

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Technique*

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Once you specify the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Defining In Vivo Findings.

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Defining In Vivo

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Design and Methods

In the Finding Design and Methods sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.

Complete the instructions as described in Adding Data and Conditions and Adding a File.

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Adding Data and Conditions

In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information that are part of your findings.

To define the matrix for the data

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complete the fields as described in the following table.

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Other options
Other options

Design and Methods FieldDescription

Description

Enter information not covered by other fields on the form.

Technique and Instrument

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Technique and instrument
Technique and instrument

Technique*

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Technique
Technique

Abbreviation

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Abbreviation
Abbreviation

DescriptionEnter an appropropriate description for the design and methods.
Instrument

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Instrument
Instrument

Once you specify the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Defining In Vivo Findings.

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Describing Findings for In Vivo Characterizations

In the Finding sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.

Complete the instructions as described in Adding Data and Conditions and Adding a File

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For an in vivo characterization, click [Other] to name the column yourself.

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Adding a File

Include PageAdding a fileAdding a fileAfter adding one or more files, continue by Adding Data and Conditions or if you have no derived data to add, return to the steps described in Adding an In Vivo Characterization.

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Sample characterizations describing distinctive characteristics or essential features of the sample determined through analytical methods, record information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by Physico-chemical characterizatics, or by data derived under In vitro and In vivo conditions.

Info
titleRead only permissions?

Based on your security permissions, you may have read-only access to characterizations and not be able to perform additional tasks.

To view a sample characterizations summary

...

Adding Data and Conditions

In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information that are part of your findings.

To define the matrix for the data

Include Page
Data and conditions1
Data and conditions1

For an in vivo characterization, click [Other] to name the column yourself.

Include Page
Data and conditions2
Data and conditions2

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Adding a File

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Adding a file
Adding a file

After adding one or more files, continue by Adding Data and Conditions or if you have no derived data to add, return to the steps described in Adding an In Vivo Characterization

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Characterization Tasks

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Managing Sample Composition Annotations | caNanoLab User's Guide| Managing Publications in caNanoLab

 

 

Info
titleRead only permissions?

Based on your security permissions, you may have read-only access to characterizations and only be able to see a characterization summary and not be able to perform additional tasks.