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If you have read-only permissions, see Viewing a Composition Summary. If you are a curator with appropriate security permissions, you can perform all the tasks described in this chapter. |
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With the appropriate security permissions, you can add or delete composition details. If the buttons do not display, you have read-only access to the item. |
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Composition Summary
With read-only access, you can review a summary of characterization information and annotations added to the sample composition summary.
To access characterization functions in the Navigation Tree
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Once you access the Composition, All tab, click Nanomaterial Entity tab to enter data or add files pertaining to the nanomaterial component of the sample. Nanomaterial Entity page has four sections and is the same for all nanomaterial composition data, except for slight customizations based what you select in the Nanomaterial Entity field.
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Follow these steps to fill in the characterizationcomposition. Links are provided for additional details.
Anchor AddNanoMaterialEntity AddNanoMaterialEntity Section What to Do Nanomaterial Entity Type* Fill in the entity type (required) and add a Description for the entity.
Info title Page Customizations The Nanomaterial Entity page contents vary slightly based on the Nanomaterial Entity you select.
[Nanomaterial] Properties Fill in the customized information according to what you selected for Nanomaterial Entity Type. Composing Elements Add information regarding the elements that compose the nanomaterial entity of the sample. File Click Add to expand the page to add one or more files whose data is relevant to the nanomaterial entity or the derivation of its data.
Copy to other Characterizations Select one or more samples in the list to which you want this composition data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact. Copy to other Samples... Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact - When you finish, click Submit to save the data to the sample.
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A biopolymer nanoparticle is a type of polymer that is produced by living organisms. In the context of nanotechnology, a biopolymer can also be a nanomaterial entity or a functionalizing entity.
To define Define biopolymer properties.
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| Name |
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Enter the name of the biopolymer. | |||||||
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| Sequence |
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Using the appropriate format, enter the complete sequence of the biopolymer. |
After defining the particle properties, continue to define Carbon Nanotube information.
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Carbon nanotubes (CNTs) are fullerene-like nanostructures that consist of graphene cylinders. The ends of the construct are closed with pentagonal-shaped rings.
To define Fill in the carbon nanotube properties as needed.
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| Average Length |
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Enter the average length of the nanotube. | |
| Length |
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| Unit | Select or enter the measurement unit type for the average length measurement of the nanotube. |
| Chirality |
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The spatial position or orientation of functional groups located within a molecule. Enter information about the chirality in the nanotube and its effect on the orientation of functional groups located on the particle. | |
| Diameter |
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Enter the measurement of the nanotube diameter, as measured from one side of the tube wall through the center of the nanotube to the opposite point on the circumference. | |
| Diameter Unit |
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Enter the measurement unit type of the nanotube diameter. | |
| Wall Type |
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After defining the particle properties, continue to define Dendrimer information.
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A dendrimer is a polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through iterative reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.
To define Fill in the dendrimer properties.
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| Branch |
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Branches are molecules that branch off of the core (like tree branches). Enter a description that represents the number of branches in the dendrimer. | |
| Generation |
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Generations are shells layered on the core of a dendrimer. Dendrimers consist of layers of chemical shells built on a core module. Each shell consists of two chemicals in the same order (A-B) and each shell is called a generation. The generations are labeled in decimal to illustrate the shell layering/consistency. For example, Generation 2.5 (G2.5) = 1 shell of A-B (1), surrounded by a second shell of A-B (2), topped off with only one chemical A within the shell (.5). As such, the layering structure would be (A-B, A-B, A) = 2.5. List the generations reflected in this dendrimer.
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After defining the particle properties, continue to define Emulsion information.
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An emulsion is a suspension of liquid within another liquid or a dispersion consisting of two or more liquid phases. In the context of caNanoLab, an emulsion nanoparticle consists of nanoparticles suspended in an emulsifying liquid.
To define Fill in the emulsion properties as needed.
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| Is Polymerized* |
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Specify whether the composition is polymerized. Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers). |
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| Polymer Name* |
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After defining the particle properties, continue to define Fullerene information.
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A fullerene is one of three known pure forms of carbon that exhibits a spherical shape with a hollow interior; named after Buckminster Fuller. The number of carbon atoms comprising fullerenes is variable; several stable spherical carbon structures containing 70 or more atoms have been documented.
To define Fill in the fullerene properties as needed.
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| Average Diameter |
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Enter themeasurement of the fullerene diameter, as measured from one side of the nanoparticle through its center to the opposite point on the circumference. | |
| Average Diameter Unit |
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Enter the measurement unit type of the fullerene diameter. | |
| Number of Carbons |
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Enter the number of carbon molecules comprising the fullerene. |
After defining the particle properties, continue to define Liposome information.
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Liposomes are substances composed of layers of lipid that form hollow microscopic spheres within which drugs or agents could be contained for enhanced safety and efficacy. Based upon its size measured in nanometer range, a liposome can be categorized as a nanoparticle.To define liposome properties
Fill in the liposome properties as needed. After defining the particle properties, continue to define Metal Particle information.
| Field | Description |
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| Polymer Name |
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| Enter the name of the liposome polymer. | |
| Is Polymerized |
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Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers). Select Yes or No, reflecting whether or not the liposome is polymerized. |
After defining the particle properties, continue to define Metal Particle information.
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A key feature that distinguishes polymers from other molecules is the repetition of a linked series of many identical, similar, or complementary monomers. A polymer nanoparticle is just that--a polymer measured in nanometer range.
To define Define the polymer properties, follow these steps:.
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| Initiator |
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| Enter the agent that initiated the polymerization. Examples are free radicals or peroxide. | |
| Is crosslinked |
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| Crosslinking is a covalent bond between two polymers or two different regions of the same polymer. Select Yes or No, indicating whether the polymer is crosslinked. | |
| Crosslink Degree |
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| Enter the percentage level of covalent linkage in the polymer. |
After defining the particle properties, continue to define Quantum Dot information.
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