NIH | National Cancer Institute | NCI Wiki  

Versions Compared

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

...

FieldDescription
Name

Enter the name of the biopolymer.

Bipolymer type

Include Page
Biopolymer type
Biopolymer type

Sequence

Using the appropriate format, enter the complete sequence of the biopolymer.

After defining the particle properties, continue Continue below to define  Carbon Nanotube carbon nanotube information.

Return to top of page

Carbon Nanotube

...

FieldDescription
Average Length

Enter the average length of the nanotube.

Length Unit

Select or enter the measurement unit type for the average length measurement of the nanotube.

Chirality

 The spatial position or orientation of functional groups located within a molecule. Enter information about the chirality in the nanotube and its effect on the orientation of functional groups located on the particle.

Diameter

Enter the measurement of the nanotube diameter, as measured from one side of the tube wall through the center of the nanotube to the opposite point on the circumference.

Diameter Unit

Enter the measurement unit type of the nanotube diameter.

Wall Type
  1. Select the appropriate description of the nanotube wall:
    • DWNT (Double-Wall Nanotube) Nanotube wall consists of two layers of graphitic carbon.
    • MWNT (Multiple-Wall Nanotube) Nanotube consists of single-walled nanotubes layered inside each other
    • SWNT (Single-wall Nanotube) Wall consists of a single layer of graphitic carbon

After defining the particle properties, continue Continue below to define Dendrimer dendrimer information.

Return to top of page

Dendrimer

...

FieldDescription
Branch

Branches are molecules that branch off of the core (like tree branches). Enter a description that represents the number of branches in the dendrimer.

Generation

Generations are shells layered on the core of a dendrimer. Dendrimers consist of layers of chemical shells built on a core module. Each shell consists of two chemicals in the same order (A-B) and each shell is called a generation. The generations are labeled in decimal to illustrate the shell layering/consistency. For example, Generation 2.5 (G2.5) = 1 shell of A-B (1), surrounded by a second shell of A-B (2), topped off with only one chemical A within the shell (.5). As such, the layering structure would be (A-B, A-B, A) = 2.5.

List the generations reflected in this dendrimer.

 

After defining the particle properties, continue Continue below to define Emulsion information.

Return to top of page

Emulsion

...

FieldDescription
Is Polymerized*

Specify whether the composition is polymerized. Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers).

Polymer Name*
  1. Enter the name of the polymer suspended in the emulsion.

After defining the particle properties, continue Continue below to define Fullerene information.

Return to top of page

Fullerene

...

FieldDescription
Average Diameter

Enter themeasurement of the fullerene diameter, as measured from one side of the nanoparticle through its center to the opposite point on the circumference.

Average Diameter Unit

Enter the measurement unit type of the fullerene diameter.

Number of Carbons

Enter the number of carbon molecules comprising the fullerene.

After defining the particle properties, continue Continue below to define Liposome information.

Return to top of page

Liposome

...

FieldDescription
Polymer NameEnter the name of the liposome polymer.
Is Polymerized

Polymerization consists of enzymatic reactions that link a series of monomers, forming a polymerized compound (polymer), usually of high molecular weight, by combination of simpler molecules (monomers).

Select Yes or No, reflecting whether or not the liposome is polymerized.

After defining the particle properties, continue Continue below to define Metal Particle metal particle information.

Return to top of page

Metal Particle

...

There are no unique metal particle properties to be defined. Continue below to define Polymer polymer information.

Return to top of page

Polymer

...

FieldDescription
InitiatorEnter the agent that initiated the polymerization. Examples are free radicals or peroxide.
Is crosslinkedCrosslinking is a covalent bond between two polymers or two different regions of the same polymer. Select Yes or No, indicating whether the polymer is crosslinked.
Crosslink DegreeEnter the percentage level of covalent linkage in the polymer.

After defining the particle properties, continue Continue below to define Quantum Dot quantum pot information.

Return to top of page

Quantum Dot

...

There are no unique quantum dot properties to be defined. Continue to define Nanomaterial Composing ElementsinformationElements.

Return to top of page

Defining Nanomaterial Composing Elements

...

Anchor
Functionalizing
Functionalizing
Adding Functionalizing Entity Composition Annotations

To add a functionalizing entity

  1. Access a sample and composition.
  2. Click the All or Functionalized Entity tab to enter data or add files pertaining to the nanomaterial component of the sample. Both tabs display five sections, but the All tab provides customizations based what you select in the Functionalized Entity Type* field.

    Tip

    Include Page
    Other options
    Other options

  3. Follow these steps to fill in the composition. Links are provided for additional details.

    Anchor
    AddFunctionalizedEntity
    AddFunctionalizedEntity

    SectionWhat to Do
    Functionalized Entity Type*

    Fill in the entity type (required).

    [Functionalizing Entity] PropertiesFill in the customized information according to what you selected for Functionalized Entity Type.
    Function InformationAdd information about the functionalizing elements of the sample.
    File

    click Add to expand the page where you can add one or more files whose data is relevant to the functionalizing entity or the derivation of its data.

    Copy to other samplesselect one or more samples in the list to which you want this composition data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.
  4. When you finish, click Submit to save the data to the sample.

...

Defining a Functionalizing Entity

To define a Fill in the following functionalized entity information as needed.

Tip

Include Page
Other options
Other options

FieldDescription

...

Chemical NameEnter the chemical name for the functionalizing entity whose type you just selected.
PubChem Data Source/PubChem ID

 

Include Page
PubChem data source
PubChem data source

 

Amount/Amount Unit

 

Include Page
Amount unit
Amount unit

 

Molecular Formula Type

 

Include Page
Molecular formula type
Molecular formula type

 

Molecular Formula

...

Enter the chemical formula of the functionalizing entity.
Activation Method

...

Select from the drop-down menu the method used to activate the functionality of the sample. Selection options are:
Activation Effect

...

Enter the functional effect of the entity.
Description

...

Enter any additional composition information that the form does not include.

When you finish, click Submit to save the data to the sample or click Reset to clear all fields on the form.

Continue to define  Functionalizing Entity type] Properties.

...

The [Funtionalizing Entity Type] Properties section opens for some Functionalizing Entity types as you make that selection. To define

Fill in the following functionalized properties for each unique functionalizing entity, enter information for the following fields.

Tip

Include Page
Other options
Other options

FieldDescription
Antibody

...

Select from the following fields:
  1. Type: Select from the drop-down list the type of antibody functioning for this sample.
  2. Isotype: Select from the drop-down list the isotype for this antibody:IgA
  3. Species:Select from the drop-down list the animal species from which the antibody was derived.
Biopolymer

...

Select from the following fields:

  1. Include Page
    Biopolymer type
    Biopolymer type
  2. Sequence: Using the appropriate format, enter the complete sequence of the biopolymer.
Small Molecule

...

Add an Alternate Name for the Small Molecule.

Continue to define Function information.

...

Defining Function Information

To define Fill in the following function information for the functionalizing entity.

Tip

Include Page
Other options
Other options

FieldDescription
Function Type

Include Page
Function type
Function type

Description

...

Enter any additional composition information that the form does not include.
  

When you finish, click Save or click Cancel to clear all fields on the form.

In the Navigation Tree, a hyperlink for the new Composition characterization is added under Functionalizing Entity.

...