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  1. Browse investigations or search investigations until you find an investigation, a study, or an assay in which you are interested.
    The search results appear.
    Example investigation as listed in search results.Image Modified

  2. Click the link corresponding with the investigation, study, or assay you are interested in exploring.
    The respective investigation details, study details, or assay details page appears.

  3. You can do the following from the details pages:

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  1. Open a Study Details page.

    An example Study Details page.Image Modified

  2. In the Visualize and Select area, click one of the entities.

    Info
    titleStudy Hierarchy

    The hierarchy of entities for studies according to the ISA-Tab standard is as follows, from less granular to more granular:

    Source > Protocol > Sample

    For example, click Source. Metadata for that source appears.

    Info

    Follow this same procedure if you want to filter on Protocol or Sample instead of Source.


    Metadata dialog box for the selected source.Image Modified

  3. From the Source Name list, click the arrow to open the list of values. Each value is a Source Name from the study file, which in this case is s_mrna.txt.
    Source Name drop-down list within the Metadata dialog box.Image Modified
  4. Click one or more values in the list to select them. Each value appears immediately below the Source Name box. To clear a selection, click the value again.
    Metadata for Source with multiple source names selected
  5. Click Filter Results.
    The Source Count reduces from the 40 original values in the unfiltered study file, s_mrna.txt, to the three selected in this procedure.
    Source Count 3, sample collection, Samples 3
  6. Options you have at this point include continuing to explore this data set, downloading the metadata of the three values you selected, downloading the selected data of the three values you selected (which includes the metadata), or clicking Clear Filters to filter a different entity.

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  1. Open an Assay Details page.

    A sample Assay Details page.Image Modified

  2. In the Visualize and Select area, click one of the entities. Note that the width of some visualizations require you to scroll by clicking the arrows at the bottom of the page.

    Info
    titleAssay Hierarchy

    The hierarchy of entities for assays according to the ISA-Tab standard is as follows, from less granular to more granular:

    Sample > Protocol > Data File

    For example, click the sample. Metadata for the sample appears.

    Info

    Follow this same procedure if you want to filter on protocol instead of sample.


    Metadata dialog box for the selected sample.Image Modified

  3. From the Sample Name list, click the arrow to open the list of values. Each value is a Sample Name from the assay file, which in this case is a_mrna_transcription_profiling_nucleotide_sequencing.txt.
    Drop-down list within the Metadata dialog box.Image Modified
  4. Click one or more values in the list to select them. To select multiple values, click one, wait for it to appear on the Metadata for Sample page, and then click the arrow again to select another value. To clear a selection, click that value again.
    Metadata dialog box with selected sample names.Image Modified

    Info

    Some entities do not have associated metadata fields on which you can filter the study or assay. In that case, when you click the icon for that entity, you see a message letting you know that no metadata fields are available.

  5. Click Filter Results.
    The Sample Count reduces from the 39 original values in the unfiltered assay file, a_mrna_transcription_profiling_nucleotide_sequencing.txt, to the 5 selected in this procedure.
    Assay Visualization, 5 Samples Selected
  6. Options you have at this point include continuing to explore this data set, downloading the metadata of the 3 values you selected, downloading the selected data of the 3 values you selected (which includes the metadata), or clicking Clear Filters to filter a different entity.

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A detailed search results window appears. The matching term, cell, is highlighted in the metadata of each file in the ISA-Tab archive.

A detailed search results window.Image Modified

To close the window, click Ok at the bottom or the x in the upper-right corner of the window.

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