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  1. Access a sample and composition.
  2. To enter add data or add files pertaining to the nanomaterial component of the sample, click the All or the Nanomaterial Entity tab or the All tab and click scroll to the Functionalized Entity section.

  3. Click Add next to Nanomaterial Entity. 

  4. Both tabs display five sections, but the All tab provides customizations based what you select in the provide customizations based on your Nanomaterial Entity Type* fieldselection.

    Include Page
    Other options
    Other options

  5. Follow these steps to fill in the composition. Links are provided for additional details.

    Anchor
    AddNanoMaterialEntity
    AddNanoMaterialEntity

    SectionWhat to Do
    Nanomaterial Entity Type*

    Fill in the entity type (required) and add a Description for the entity.

    [Nanomaterial] PropertiesBased on the Entity Type, fill in the appropriate Properties.
    Composing ElementsAdd information regarding the elements that compose the nanomaterial entity of the sample.
    File

    Click Add to expand the page to add one or more files whose data is relevant to the nanomaterial entity or the derivation of its data.

    Copy to other samples with the same primary organization?Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.
  6. When you finish, click Submit to save the data to the sample.

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FieldDescription
Composing Element Type*Select from the drop-down list the type of composing element comprising this nanomaterial (required).
Chemical Name*Enter the chemical name given to the atomic or molecular structure that composes the center of the nanoparticle (required).
Crosslink DegreeEnter the percentage level of covalent linkage in the polymer.
PubChem Data Source/PubChem ID

Include Page
PubChem data source
PubChem data source

Amount/Amount Unit

Include Page
Amount unit
Amount unit

Molecular Formula Type

Include Page
Molecular formula type
Molecular formula type

Molecular FormulaEnter the chemical formula of the nanoparticle.
DescriptionEnter a description for the composing element.
Inherent Function

Inherent function is the characteristic behavior of a sample that results from the chemical and physical composition and properties of the entity.

Click the Add button to expand the page where you can enter this information.

Function Type

Include Page
Function type
Function type

DescriptionEnter any additional function information for the nanomaterial entity that the form does not already include.

Click Save to add the inherent function details to the nanomaterial entity Once you add the composing element, click Save or Cancel to just close the window.

After defining composing elements, continue to add supporting documentation files.

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Adding a File

Include Page
Adding a file
Adding a file

After adding one or more files, return to the steps described in Adding Nanomaterial Entity Composition Annotations.

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Anchor
Functionalizing
Functionalizing
Adding Functionalizing Entity Composition Annotations

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  1. Access a sample and composition.
  2. To enter add data or add files pertaining to the nanomaterial component of the sample, click the All or the Functionalized Entity tab or the All tab and click Add on the Physico-chemical Characterization bar. Both tabs display five sections, but the All tab provides customizations based what you select in the Functionalized Entity Type* fieldscroll to the Functionalized Entity section.

  3. Click Add next to Functionalized Entity.

  4. Both tabs provide customizations based on your Functionalizing Entity Type* selection.

    Include Page
    Other options
    Other options

  5. Follow these steps to fill in the composition. Links are provided for additional details.

    Anchor
    AddFunctionalizedEntity
    AddFunctionalizedEntity

    SectionWhat to Do
    Functionalized Entity Type*

    Fill in the entity type (required).

    [Functionalizing Entity] PropertiesBased on the Entity Type, fill in the appropriate Properties.
    Inherent Function InformationAdd information about the functionalizing elements of the sample.
    File

    Click Add to expand the page where you can add one or more files whose data is relevant to the functionalizing entity or the derivation of its data.

    Copy to other samples with the same primary organization?Select one or more samples in the list to which you want this composition data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.
  6. When you finish, click Submit to save the data to the sample.

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Defining

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a Functionalizing Entity

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Fill in the following functionalized entity information as needed.

Include Page
Other options
Other options

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If you select one of the following Functionalizing Entity Types, the Properties section opens and you must fill in additional information.

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FieldDescriptionAntibodySelect from the following fields:Type:  
FieldDescription
Chemical NameEnter the chemical name for the functionalizing entity whose type you just selected.
PubChem Data Source/PubChem ID

Include Page
PubChem data source
PubChem data source

Amount/Amount Unit

Include Page
Amount unit
Amount unit

Molecular Formula Type

Include Page
Molecular formula type
Molecular formula type

Molecular FormulaEnter the chemical formula of the functionalizing entity.
Activation Method

Select from the drop-down

list the type of antibody functioning for this

menu the method used to activate the functionality of the sample.

  • Fab
  • ScFv
  • whole
  • Isotype:   Select from the drop-down list the isotype for this antibody:IgA
  • Species:  Select from the drop-down list the animal species from which the antibody was derived.
  • Biopolymer

    Select from the following fields.

    Include PageBiopolymer typeBiopolymer type
  • Sequence: Using the appropriate format, enter the complete sequence of the biopolymer.
  • Small MoleculeAdd an Alternate Name for the Small Molecule
    Info
    If you do not have to activate the entity, select does not require activation.
    Activation EffectEnter the functional effect of the entity.
    DescriptionEnter any additional composition information that the form does not include.

    Once you add the inherent function, click Save or Cancel to close the window.

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    Defining

    ...

    [Functionalizing Entity

    ...

    type] Properties
    Anchor
    functionalizingEntityProperties
    functionalizingEntityProperties

    If you select one of the following Functionalizing Entity Types, the Properties section opens and you must fill in additional informationFill in the following functionalized entity information as needed.

    Include Page
    Other options
    Other options

    Field
    Entity Type
    Description
    Additional Properties
    Chemical Name
    Antibody
    Enter the chemical name for the functionalizing entity whose type you just selected.PubChem Data Source/PubChem ID Include Page
    Select from the following fields:
    • Type:   Select from the drop-down list the type of antibody functioning for this sample.
    • Isotype:   Select from the drop-down list the isotype for this antibody:IgA
    • Species: 
    PubChem data sourcePubChem data sourceAmount/Amount Unit Include PageAmount unitAmount unitMolecular Formula Type Include PageMolecular formula typeMolecular formula typeMolecular FormulaEnter the chemical formula of the functionalizing entity.Activation Method
    • Select from the drop-down
    menu the method used to activate the functionality of the sample.
    Info
    If you do not have to activate the entity, select does not require activation.
    Activation EffectEnter the functional effect of the entity.
    • list the animal species from which the antibody was derived.
    Biopolymer

    Select from the following fields.

    • Include Page
      Biopolymer type
      Biopolymer type
    • Sequence: Using the appropriate format, enter the complete sequence of the biopolymer.
    Small MoleculeAdd an Alternate Name for the Small Molecule.

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    Defining Function Information

    Fill in the following inherent function information for the functionalizing entity.

    Include Page
    Other options
    Other options

    FieldDescription
    Function Type

    Include Page
    Function type
    Function type

    DescriptionEnter any additional composition information that the form does not include.

    When you finishare done, click Submit to save the data to the sample or click Reset to clear all fields on the form.

    Continue to define functionalizing entity properties.

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    Defining Function Information

    Fill in the following inherent function information for the functionalizing entity.

    ...

    Save or Cancel to close the window.

    Info
    In the Navigation Tree, a hyperlink for the new Composition characterization is added under the Functionalizing Entity.

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    Adding a File

    To add results in the form of supporting documents to the functionalizing entity, follow these steps:

    Include Page
    Adding a file
    Adding a file

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    Anchor
    ChemicalAssociation
    ChemicalAssociation
    Adding Chemical Association Composition Annotations

    Using the [Sample] Composition Chemical Association subcategory, you can enter basic annotation information describing the chemical association(s) of the sample and/or functionalizing entities of the sample.

    Info
    titleChemical association requirement

    To enter chemical association information, you must enter at least two composing elements and/or at least one functionalizing entity for the sample entity.

    To add a chemical association

    1. Access a sample and composition.
    2. Add the required nanomaterial and functionalizing entity information.
    3. To add data or files to the nanomaterial component of the sample, click the Chemical Association tab or the All tab and scroll to the Chemical Association section.

    4. Click Add next to Chemical Association.

    5. Both tabs provide customizations based on your Association Type* selection.

      Include Page
      Other options
      Other options

    6. Follow these steps to fill in the association. Links are provided for additional details.

      Anchor
      AddFunctionalizedEntity
      AddFunctionalizedEntity

      SectionWhat to Do
      Association Type*

      Fill in the chemical association type (required).

      Description

      Enter any additional information that describes the chemical association of the two elements.

      Elements Information In the Elements Information section, both Element boxes select the nanomaterial or functionalizing entities for which you are defining the chemical association. These have been previously defined for the sample you are annotating. For each selection you make, another drop-down list appears displaying entities relating to your previous selection. Make the appropriate selections in each.The arrow between the Element text boxes symbolizes the association between the two.
      File

      Click Add to expand the page where you can add one or more files whose data is relevant to the functionalizing entity or the derivation of its data.

      Copy to other samples with the same primary organization?Select one or more samples in the list to which you want this composition data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

      When you are finished, click Submit to save the association to the sample

    When you finish, click Save. In the Navigation Tree, a hyperlink for the new Composition characterization is added under Functionalizing Entity.

    Continue to add files, if needed.

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    Adding a File

    To add results in the form of supporting documents to the functionalizing entity, follow these steps:

    ...

    As appropriate, continue the process described in Adding Functionalizing Entity Composition Annotations or Adding Chemical Association Composition Annotations.

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    ...

    Using the [Sample] Composition Chemical Association subcategory, you can enter basic annotation information describing the chemical association(s) of the sample and/or functionalizing entities of the sample.

    Info
    titleChemical association requirement

    To enter chemical association information, you must enter at least two composing elements and/or at least one functionalizing entity for the sample entity.

    To enter chemical association information

    ...

    1. Once you enter the essential nanomaterial entity and functionalizing entity information under the Composition category, click the Add button corresponding to Chemical Association on the All tab or select the Chemical Association tab itself where you can click the Add button.
    2. The page that opens is organized into three sections. Select from the drop-down list the Association Type (required). Options include:
      Description: Enter any additional information that describes the chemical association of the two elements.
    3. In the Elements Information section, both Element boxes select the nanomaterial or functionalizing entities for which you are defining the chemical association. These have been previously defined for the sample you are annotating. For each selection you make, another drop-down list appears displaying entities relating to your previous selection. Make the appropriate selections in each.The arrow between the Element text boxes symbolizes the association between the two.
    4. In the File section, click Add to expand the page where you can add one or more files whose data is relevant to the nanomaterial entity or the derivation of its data

      .

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    Adding Composition Files

    ...

    1. Click Composition on the Navigation Tree, and click the Composition File tab.
    2. Composition File Add button.
      Next to Composition File, click Add. You can add as many files as you wish.

    3. Select Upload, then click the Browse button to navigate to the report or publication to be associated with the sample,
      – OR –
      Click Enter File URL and enter the URL where the document is located.
    4. For the file to be added, specify or enter the following:
      1. File Type (required): Document, Graph, Image, Spreadsheet
      2. File Title (required)
      3. Keywords to associate with the file
      4. Description: Enter any additional information for the file that the form does not already include.
    5. In the Visibility field, select the group(s) to be granted access to the selected file.
    6. Click Submit to add the referenced file(s) to the sample. The file is added.

      Tip
      titleEditing and Deleting a File

      Once you add a composition file, you can remove the file or edit the composition file information.

      To delete a file, click Edit and on the Edit Composition File page, click Delete. To update the file information, click Edit and on the Edit Composition File page, make the changes and click Update. The list of files is updated.

      After adding one or more files, continue the process described in Adding Chemical Association Composition Annotations

      .

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    Managing Samples in caNanoLab | caNanoLab User's Guide| Managing Sample Characterizations