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If you have read-only access, you canView a Characterizations Summary.

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PhysicoChemical
PhysicoChemical
Adding a Physico-Chemical Characterization

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  1. Access a sample and characterization.

  2. Click the All tab or the Physico-Chemical Characterizations tab and click Add next to Physico-chemical Characterization.

  3. Both tabs provide customizations based on your Characterization Type* selection.

  4. Follow these steps to fill in the characterization. Links are provided for additional details.

    Anchor
    AddPhysicoChemical
    AddPhysicoChemical

    SectionWhat to Do
    Physico-Chemical CharacterizationFill in the general information about the characterization.
    Characterization PropertiesDisplays only for Physical State, Shape and Solubility characterizations. Define the properties for the characterization, if applicable.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.
    Copy to other Samples...Select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

  5. When you finish, click Submit to save the data to the sample.

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Fill in the following characterization information. Include PageOther optionsOther options

, Type, select other_pc, select Characterization Name characterization Characterization Name .
Adding a New Characterization NameImage Removed
FieldDescription
Characterization Type*

The Characterization Type is already selected as Physico-Chemical Characterization.

Characterization Name*

You must select the name of the Characterization you want to add

or select an "other" option to create a new or select from an existing, non-standard Assay Type

.

To select an existing, non-standard
Assay Type

The field populates automatically based on Characterization

Name selection.

To create a new, non-standard Assay Type

  • Select other.
  • Enter a New
  • Assay Type, and click Add. 
  • The new
  • Assay Type is added to the
  • list
Assay Type

The field populates automatically with your selection in Characterization Name.

  • With Characterization Name, other_pc, select from existing, non-standard Assay Types.
    • With Characterization Name, other, create a new, non-standard Assay Type
    • .
    Protocol Name – VersionIf this field is available, select from the drop-down list the a protocol from which the data is derived. A hyperlink of If displayed, click the hyperlink to the protocol text file may appear. Click the hyperlink to open or save the file.
    Characterization SourceSelect from the drop-down list or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
    Characterization DateSelect from the calendar or enter the date the characterization was made . Acceptable format: (dd/mm/yyyy).

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    Physico-Chemical Characterization Properties
    Physico-Chemical Characterization Properties
    Defining Physico-Chemical

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    Characterization3 Properties

    The [Characterization ] Properties section opens only for the characterizations listed in the table below. Fill in the following Properties information as needed. Include PageOther optionsOther options, as needed.

    CharacterizationProperty FieldsField Options

    Physical State

    Type

    Select the appropriate type from among the following options:.

    Shape Properties

    Type (required)

    Select from the drop-down list the appropriate shape type:.

    Shape Properties

    Aspect Ratio

    Enter the shape aspect ratio.

    Shape Properties

    Minimum,/Maximum Dimensions

    Enter the minimum and maximum dimensions of the sample, as well as the units of measurement.

    Solubility Properties

    Solvent

    Select from the options or enter the name.

    • 3D-cube
    • 3D-cylinder
    • alcohol
    • phosphate-buffered saline
    • saline
    • THF
    • water
    Solubility PropertiesCritical Concentration

    Enter appropriate values for the critical concentration, then select the appropriate units for those values.

    Solubility PropertiesIs Soluble?Select Yes or No as to whether the solvent is soluble.

    Surface Properties

    Is Hydrophobic?

    Indicate with Yes or No whether the surface is hydrophobic.

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    Fill in the following Design and Methods information as needed. Include PageOther optionsOther optionsneeded.

    Design and Methods FieldDescription

    Design and Methods Description

    Enter a description for the characterization design and methods.

    Info
    titleExtra lines add

    If you include an extra line between text in the Design and Methods Description, the line separation is preserved when you save or update the characterization.

    Technique and Instrument

    Include Page
    Technique and instrument
    Technique and instrument

    Technique*

    Include Page
    Technique
    Technique

    Abbreviation

    Include Page
    Abbreviation
    Abbreviation

    DescriptionEnter a description of the technical and instrument.
    Instrument

    Include Page
    Instrument
    Instrument

    Once you enter the data, click Click Save to save add the information to the sample or Cancel to close the mini- window without saving data.Continue to define Physico-Chemical Findings.

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    Describing Findings for Physico-Chemical Characterization

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    To define the data and conditions matrix

    Include Page
    Other optionsOther options
    Include Page
    Data and conditions1
    Data and conditions1

    ...

    Include Page
    Data and conditions2
    Data and conditions2

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    Adding a File to a Physico-Chemical Characterization

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    File to a Physico-Chemical Characterization

    Include Page
    Adding a file
    Adding a file
    .

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    Anchor
    InVitro
    InVitro
    Adding an In Vitro Characterization

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    Fill in the following characterization information.includeOther optionsOther options

    FieldDescription
    Characterization Type*

    The Characterization Type is already selected as In Vitro Characterization.

    Characterization Name*

    You must select the name of the Characterization you want to add or select an "other" option to create a new or select from an existing, non-standard Assay Type.

    • To select an existing, non-standard Assay Type, based on Characterization Type, select other_vt.
    • To create a new, non-standard Assay Type, select other. Enter a New Characterization Name, and click Add.  The new characterization is added the Characterization Name list.
      Adding a New Characterization Name
    Assay Type

    The field populates automatically with options displayed for in vitro characterization selections: Blood Contact, Cytotoxicity, Immune Cell Function, Oxidative Stress, Sterility and Targeting.

    • With Characterization Name, other_vt, select from existing, non-standard Assay Types.
    • With Characterization Name, other, create a new, non-standard Assay Type.
    Protocol Name – Version

    If available, select the protocol from which the data is derived.

    • A hyperlink to the protocol text file should appear (if the protocol is not private to the user and the protocol file exists). However, protocol files are not required. Click the hyperlink to open or save the file.
    • A hyperlink to the protocol text file should appear (if the protocol is not private to the user and the protocol file exists - ie. protocol files are not required).
    Characterization SourceSelect or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
    Characterization DateSelect from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

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    Defining In Vitro Characterization Properties

    The [Characterization ] Properties section opens only when you select the following characterizations in the Summary section. To define properties for each unique characterization, enter information for the following fields. Include PageOther optionsOther options

    For Cytotoxicity, enter the appropriate Cell Line.

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    Fill in the following Design and Methods information as needed. Include PageOther optionsOther options

    Design and Methods FieldDescription
    Design and Methods Description

    Enter a description for the characterization design and methods.

    Info
    titleExtra lines add

    If you include an extra line between text in the Design and Methods Description, the line separation is preserved when you save or update the characterization.

    Technique and Instrument

    Include Page
    Technique and instrument
    Technique and instrument

    Technique*

    Include Page
    Technique
    Technique

    Abbreviation

    Include Page
    Abbreviation
    Abbreviation

    DescriptionEnter a description of the technique and instrument.
    Instrument

    Include Page
    Instrument
    Instrument

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    In the Data and Conditions segment of the window, add or import data values and specify other information that is part of your findings (like laboratory conditions).

    Include PageOther optionsOther optionsTo define the matrix for the data

    ...

    Fill in the following characterization information. Include PageOther optionsOther options

    FieldDescription
    Characterization Type*

    The Characterization Type is already selected as In Vivo Characterization.

    Characterization Name*

    You must select the name of the Characterization you want to add or select an "other" option to create a new or select from an existing, non-standard Assay Type.

    Info
    If you select Pharmacokinetics and Toxicity, there are no customizations on this Characterization page based on either of these selections.
    • To select an existing, non-standard Assay Type, based on Characterization Type, select other_vv or other_ex_vv.
    • To create a new, non-standard Assay Type, select other. Enter a New Characterization Name, and click Add.  The new characterization is added the Characterization Name list.
      Adding a New Characterization Name
    Assay Type

    Leave this blank or select a type.

    • With Characterization Name, other_vv or other_ex_vv, select from existing, non-standard Assay Types.
    • With Characterization Name, other, create a new, non-standard Assay Type.
    Protocol Name – VersionSelect from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.
    Characterization SourceSelect from the drop-down list or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
    Characterization DateSelect from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

    ...

    Fill in the following Design and Methods information as needed. Include PageOther optionsOther options

    Design and Methods FieldDescription

    Design and Methods Description

    Enter a description for the characterization design and methods.

    Info
    titleAdding extra lines

    If you include an extra line between text in the Characterizations free text, Design and Methods Description, the line separation is preserved when you save or update the characterization.

    Technique and Instrument

    Include Page
    Technique and instrument
    Technique and instrument

    Technique*

    Include Page
    Technique
    Technique

    Abbreviation

    Include Page
    Abbreviation
    Abbreviation

    DescriptionEnter a description of the technique and instrument.
    Instrument

    Include Page
    Instrument
    Instrument

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