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  1. Access a sample and characterization.
  2. Click the All tab or the Physico-Chemical Characterizations tab and click Add next to Physico-chemical Characterization.

  3. Both tabs provide customizations based on your Characterization Type* selection.

  4. Follow these steps to fill in the characterization. Links are provided for additional details.

    Anchor
    AddPhysicoChemical
    AddPhysicoChemical

    SectionWhat to Do
    Physico-Chemical CharacterizationFill in the general information about the characterization.
    Properties

    If you select one of the following characterization types, you need to fill in additional properties.

    • Physical State
    • Shape
    • Solubility
    • Surface
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample. Import as many .csv files as you wish or add derived data manually.

    Click Add to expand the section, then and add data findings and add supporting documents to the characterization.

    Analysis and ConclusionEnter any relevant analyses and conclusions reached by the data.

    Copy to Other Samples with the Same Primary Organization

    Select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

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  1. Access a sample and characterization.
  2. Click the All tab or the In Vitro Characterizations tab and click Add next to In Vitro Characterization.

  3. Both tabs provide customizations based on your Characterization Type* selection.

  4. Follow these steps to fill in the characterization. Links are provided for additional details.

    Anchor
    AddInVitroCharacterization
    AddInVitroCharacterization

    SectionWhat to Do
    In Vitro CharacterizationFill in the general information about the characterization.
    Properties

    If you select one of the following characterization names, you need to fill in additional properties.

    • Cytotoxicity
    • Enzyme Induction
    • Transfection
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample. Import as many .csv files as you wish or add derived data manually.

    Click Add to expand the section, then and add data findings and add supporting documents to the characterization.

    Analysis and ConclusionEnter any relevant analyses and conclusions reached by the data.
    Copy to Other Samples with the Same Primary OrganizationSelect samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

...

  1. Access a sample and characterization.
  2. Click the All tab or the In Vitro Characterizations tab and click Add next to In Vitro Characterization.

  3. Both tabs provide customizations based on your Characterization Type* selection.

    Follow these steps to fill in the characterization. Links are provided for additional details.

    SectionWhat to Do
    In Vivo CharacterizationFill in the general information about the characterization.
    PropertiesDisplays for in vivo characterizations.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample. Import as many .csv files as you wish or add derived data manually.

    Click Add to expand the section, then and add data findings and add supporting documents to the characterization.

    Analysis and ConclusionEnter any relevant analyses and conclusions reached by the data.
    Copy to Other Samples with the Same Primary Organization

    Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

  4. When you are finished, click Submit to save the data to the sample.

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The following table lists tasks that require Curator privileges. If a button does not display, you have read-only access to the data.

Add a file to
TaskHow to
Anchor
AddFileAddFile

Printing a characterization

To add results in the form of supporting documents, such as a graphic, spreadsheet or images to a characterization

  1. Edit the characterization.
  2. From the In the Finding section, next to Files, click Add.
  3. Upload, browse, and select the file or enter the file's URL where the document is located.
  4. Complete the following.
    1. Select the File Type (required), Document, Graph, Image, Movie, or Spreadsheet.
    2. Enter the File Title (required).
    3. Specify Keywords to associate with the file
    4. Enter a Description of additional information of the file.
  5. Click Submit to add the file(s) to the sample.

Tip

You can add as many files as you wish.

Printing a characterization

From the All tab's characterizations summary, click Print at the top right of the page.

Exporting characterizations

From the All tab's characterizations summary, click Export at the top right of the page.

From the All tab's characterizations summary, click Print at the top right of the page.

Exporting characterizations

From the All tab's characterizations summary, click Export at the top right of the page.

Editing a characterization

  1. From the All tab's characterizations summary, click Edit at the right of the characterization section you want to change.
  2. The Characterization opens and you can edit it as needed.

Copying a characterization

The characterization files and/or derived data for a sample can be copied to other samples from the same primary point of contact.

  1. The Characterization opens and at the bottom of the page, in the Copy to other samples... section, select one or more samples with the same primary point of contact.
  2. Click Also copy finding data and conditions?.
  3. Click Submit to copy the characterization.

Deleting a characterization

Info
titleDeleting a characterization

This deletes a characterization(s) from the selected sample. If the characterization(s) was copied to other samples, the characterization is not removed from those samples.

To delete a characterization for a selected sample

  1. From the All tab's characterizations

Editing a characterization

  1. From the All tab's characterizations summary, click Edit at the right of the a characterization section you want to change.
  2. The Characterization opens and you can edit it as needed, and click Delete.

Copying a characterization

  1. The
characterization files and/or derived data for a sample can be copied to other samples from the same primary point of contact.
  1. The Characterization opens and at the bottom of the page, in the Copy to other samples... section, select one or more samples with the same primary point of contact.
  2. Click Also copy finding data and conditions?.
  3. Click Submit to copy the characterization.

Deleting a characterization

Info
titleDeleting a characterization

This deletes a characterization(s) from the selected sample. If the characterization(s) was copied to other samples, the characterization is not removed from those samples.

To delete a characterization for a selected sample

  1. From the All tab's characterizations summary, click Edit at the right of a characterization section.
  2. The Characterization opens, and click Delete.
  3. The deleted characterization is placed in the sample archive for historical purposes.

Defining the Characterization

When you are adding a characterization, fill in the following characterization information.

...

This is already filled in with Physico-Chemical, In Vivo, Ex Vivo, or Ex (required) when you click the tab of the same name or add one from the All tab.

...

Select the name of the characterization (required).

Info
titleCharacter Type Notes
  • Physico-Chemical: If you select Cytoxicity, Enzyme Reduction, Target, or Transfection, you have to complete additional properties. To select an existing, non-standard Assay Type, select other_pc.
  • In Vitro: If you select Cytoxicity, Enzyme Reduction, Target, or Transfection, you have to complete additional properties. To select an existing, non-standard Assay Type, select other_vt.
  • In Vivo: To select an existing, non-standard Assay Type, select other_vv or other_ex_vv.

To create a new, non-standard Assay Type

    1. Select other.
    2. Enter a New Characterization Name and click Add, and the new characterization is added the Characterization Name list.
      Adding a New Characterization NameImage Removed

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    1. Select other.
    2. Enter a New Assay Type and click Add, and the new Assay Type is added to the list.

...

Defining Characterization Design and Methods

When you are adding a characterization, fill in the following design, methods, and techniques used.

...

Design and Methods Description

...

Enter a description for the characterization design and methods.

Info
titleAdding extra lines

If you include an extra line between text in the Characterizations free text, Design and Methods Description, the line separation is preserved when you save or update the characterization.

...

Technique and Instrument

...

Technique*

...

When you are finished, click Save or Cancel to close the section without saving.

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Adding Findings to a Characterization

To add findings to a characterization, you can add data directly to Data and Conditions by creating columns and adding data manually or you can import as many .csv files as needed. Information can include laboratory conditions, pH, or temperature. You can add as many files as you wish.

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  1. Save the spreadsheet of data values to a csv (comma-separated value) file.
  2. Click Import csv and select and follow the prompts to add the data file to the Findings Info.
    Import CSV buttonImage Removed
  3. The columns and data are added to Data and Conditions.

...

Info

Whether you imported or added information manually, you can preface each data value with one of the following: Maintain the default, equal to (=), or select greater than (>), less than (<), or infinity (approximate).
Adding Data and Conditions values to the tableImage Removed

  1. deleted characterization is placed in the sample archive for historical purposes.

Defining the Characterization

When you are adding a characterization, fill in the following characterization information.

CompleteHow to
Characterization Type*

This is already filled in with Physico-Chemical, In Vivo, Ex Vivo, or Ex (required) when you click the tab of the same name or add one from the All tab.

Characterization Name*

Select the name of the characterization (required).


Info
titleCharacter Type Notes
  • Physico-Chemical: If you select Cytoxicity, Enzyme Reduction, Target, or Transfection, you have to complete additional properties. To select an existing, non-standard Assay Type, select other_pc.
  • In Vitro: If you select Cytoxicity, Enzyme Reduction, Target, or Transfection, you have to complete additional properties. To select an existing, non-standard Assay Type, select other_vt.
  • In Vivo: To select an existing, non-standard Assay Type, select other_vv or other_ex_vv.

To create a new, non-standard Assay Type

    1. Select other.
    2. Enter a New Characterization Name and click Add, and the new characterization is added the Characterization Name list.
      Adding a New Characterization NameImage Added
Assay Type
    1. Select other.
    2. Enter a New Assay Type and click Add, and the new Assay Type is added to the list.
Protocol Name – VersionIf available, select a protocol from which the data is derived. If displayed, click the hyperlink to the protocol text file to open or save the file.
Characterization SourceSelect or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
Characterization DateSelect or enter the date the characterization was made (dd/mm/yyyy).

Defining Characterization Design and Methods

When you are adding a characterization, fill in the following design, methods, and techniques used.

Design and Methods FieldDescription

Design and Methods Description

Enter a description for the characterization design and methods.

Info
titleAdding extra lines

If you include an extra line between text in the Characterizations free text, Design and Methods Description, the line separation is preserved when you save or update the characterization.

Technique and Instrument

Include Page
Technique and instrument
Technique and instrument

Technique*

Include Page
Technique
Technique

Abbreviation

Include Page
Abbreviation
Abbreviation

DescriptionEnter a description of the technique and instrument.
Instrument

Include Page
Instrument
Instrument

When you are finished, click Save or Cancel to close the section without saving.

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Adding Data Findings to a Characterization

To add findings to a characterization, you can add data directly to Data and Conditions by creating columns and adding data manually or you can import as many .csv files as needed. Information can include laboratory conditions, pH, or temperature. You can add as many files as you wish.

  1. Add data values to Data and Conditions.
    1. To import a file of data values
      1. Save the spreadsheet of data values to a csv (comma-separated value) file.
      2. Click Import csv and select and follow the prompts to add the data file to the Findings Info.
        Import CSV buttonImage Added
      3. The columns and data are added to Data and Conditions.
    2. To add the data values manually
      1. Specify the number of columns and rows for the matrix, and click Update.
        Manually adding Data and Conditions data valuesImage Added
      2. Add the data values to the rows.

    Info

    Whether you imported or added information manually, you can preface each data value with one of the following: Maintain the default, equal to (=), or select greater than (>), less than (<), or infinity (approximate).
    Adding Data and Conditions values to the tableImage Added

  2. To define a column, click an underlined column heading.
    Clicking columnImage Added
    The Column Definition panel displays.
    Defining the Findings column definitionImage Added
  3. Select a Column Type, Datum or Condition.
  4. Select a Column Name or select other and add a new one.

    Info
    titleColumn Notes
    You can add up to three cell viability Column Names, including cell viability, cell viability B, and cell viability C. You can further identify the column with the Column Value Type.


    1. For Column Type, Datum, the following characterization(s) display customized Column Name options.

      Characterization TypeColumn Type and Column Name Option(s)
      Physico-Chemical
      • MolecularMolecular Weight
      • Purity% purity for sample
      • RelaxivityR1, R2, T1, T2
      • SizePD1, Peak N , RMS size, Z Average
      • Surfacecharge, zeta potential
      In Vitro

      Enzyme Induction – % of Control

      In VivoClick Other to name the column yourself.
    2. For Column Type, Condition, all characterizations provide the Column Name options in the left column of the following table. The Column Name autopopulates the Condition Property options in the right column.

      Column Type, Condition Autopopulates Column NameColumn Name Autopopulates
      Condition Property

      Centrifugation

      N/A

      Culture Media

      media type, serum percentage

      Electromagnetic Radiation

      bandwidth, frequency, time, wavelength

      Freeze Thaw

      N/A

      Long Term Storage

      lyophilized, time

      Lyophilization

      time

      pH

      N/A

      Sample concentration

      N/A

      Short Term Storage

      lyophilized, time

      Solvent Media

      ion concentration, ionic strength, molecular formula, osmolality, serum percentage, with serum

      Sonication

      number of pulses, pulse duration

      Temperature

      N/A

  5. To further identify a column, select a Column Value Type.

    Info
    Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).


  6. Select a Column Value Unit, or select other and add one.
  7. If you want the same value to fill all rows in a column, add a Constant Value.

    Info
    titleFor Column Value Type, boolean
    For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.
  8. Click Save, and the column(s) are updated.

    Info

    If needed, click Set Column Order to change the order of the column headings in the matrix.


  9. Click Save in the Finding section.

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Anchor
AddFile
AddFile
Adding Supporting Documents to a Characterization

To add results in the form of supporting documents, such as a graphic, spreadsheet or images to a characterization

  1. Edit the characterization.
  2. From the In the Finding section, next to Files, click Add.
  3. Upload, browse, and select the file or enter the file's URL where the document is located.
  4. Complete the following.
    1. Select the File Type (required), Document, Graph, Image, Movie, or Spreadsheet.
    2. Enter the File Title (required).
    3. Specify Keywords to associate with the file
    4. Enter a Description of additional information of the file.
  5. Click Submit to add the file(s) to the sample.

Tip

You can add as many files as you wish

...

Select a Column Name or select other and add a new one.

Info
titleColumn Notes
You can add up to three cell viability Column Names, including cell viability, cell viability B, and cell viability C. You can further identify the column with the Column Value Type.

For Column Type, Datum, the following characterization(s) display customized Column Name options.

...

  • MolecularMolecular Weight
  • Purity% purity for sample
  • RelaxivityR1, R2, T1, T2
  • SizePD1, Peak N , RMS size, Z Average
  • Surfacecharge, zeta potential

...

Enzyme Induction – % of Control

...

For Column Type, Condition, all characterizations provide the Column Name options in the left column of the following table. The Column Name autopopulates the Condition Property options in the right column.

...

Centrifugation

...

N/A

...

Culture Media

...

media type, serum percentage

...

Electromagnetic Radiation

...

bandwidth, frequency, time, wavelength

...

Freeze Thaw

...

N/A

...

Long Term Storage

...

lyophilized, time

...

Lyophilization

...

time

...

pH

...

N/A

...

Sample concentration

...

N/A

...

Short Term Storage

...

lyophilized, time

...

Solvent Media

...

ion concentration, ionic strength, molecular formula, osmolality, serum percentage, with serum

...

Sonication

...

number of pulses, pulse duration

...

Temperature

...

N/A

To further identify a column, select a Column Value Type.

Info
Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).

...

If you want the same value to fill all rows in a column, add a Constant Value.

Info
titleFor Column Value Type, boolean
For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.

Click Save, and the column(s) are updated.

Info

If needed, click Set Column Order to change the order of the column headings in the matrix.

...

.

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Managing Sample Composition Annotations | caNanoLab User's Guide| Managing Publications in caNanoLab