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Since 1997, EVS has worked with many partners to build shared content and services, so that information can be effectively exchanged, interpreted and analyzed while minimizing overall effort and cost. Much of this content has been created and published using NCI Thesaurus and NCI Metathesaurus, as outlined in the following sections and described in more detail in the individual user profiles later, where other shared development efforts are also described.
NCI Thesaurus (NCIt)NCI Thesaurus (NCIt) is NCI's core reference terminology. Over the last 10 years, it has also been adopted by FDA, CDISC, NCPDP and other partners as a shared standards development and coding environment, allowing participants to compare and harmonize with each other's content while taking advantage of full-text definitions, codes, and other features. About 50,000 out of the 120,000 current NCIt concepts have terms from both EVS and from one or more of these other sources. The chart below gives a detailed breakdown of the main areas of overlapping tagged content. Note that some partners have used NCI terms rather than tagging their own, so these figures understate the true extent of cross-source sharing. NCIt concepts with terms from tagged outside sources (11.09d: September 2011) NCIt concepts with tagged synonyms from each outside source (13.03d: March 2013)
NCI Metathesaurus (NCIm)NCI Metathesaurus (NCIm) was started in the late 1990s to gather up, translate between, and publish the many terminologies used by NCI, including some created in part or whole within NCI. Development of NCI Thesaurus started within NCIm as NewPDQ, an effort to extend and restructure the PDQ Terminology long used to code cancer clinical trial, research and public information resources. NCIm continues to provide a vital environment for EVS collaboration with NCI and other partners to develop, map and publish terminologies of shared interest, and responds to the requirements of a broad range of stakeholders within the cancer research and biomedical community. NCIt tagged content from outside sources is imported into NCIm with separate source tags. NCIt-derived sources are grouped separately below. The NCIm tags are mostly identical or very similar to those in NCIt; exceptions are CADSR, converted to NCI; HL7, converted to NCI-HL7; and CTRM, which is not imported. NCIm sources and the number of concepts to which each contributes (201908: August 2019)
HUGO HUGO Gene Nomenclature, 2010_05 11,532 ICD10 ICD10, 1998 1,004 ICD10AE ICD10, American English Equivalents, 1998
ICPC2ICD10ENG ICPC2 - ICD10 Thesaurus, 200412 80,206 | Logical Observation Identifier Names and Codes, 232LNC
19,880 MTHFDA Metathesaurus FDA National Drug Code Directory, 2010_08_02
94 MTHICPC2ICD107B ICPC2 - ICD10 Thesaurus, 7-bit Equivalents, 0412 76 MTHICPC2ICD10AE ICPC2 - ICD10 Thesaurus, American English Equivalents, 0412
Metathesaurus Version of Minimal Standard Terminology Digestive Endoscopy, 2001 12,969 MTHSPL Metathesaurus FDA Structured Product Labels, 2010_08_27 478,187 NCBI NCBI Taxonomy, 2010_04_29 135 NCIMTH NCI Metathesaurus 38,863 NDFRT National Drug File, 2010_09_07 1,781 | NPO: NanoParticle Ontology for Cancer Nanotechnology Research, 2010_10_31NPO
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