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Comment: Revised based on my current understanding.

If you need to move a large volume of data, you can do so using a Globus endpoint. DME uses Globus for high performance transfer of large files. Endpoints are destinations that represent locations on a file transfer service server, such as gridftp.  The In DME CLU, you can choose to use Globus for file transfer. In DME GUI, the following activities in DME require a Globus endpoint:

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