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Chair: 

Luigi Ferrucci M.D., Ph.D., National Institute on Aging


Co-chairs

Gabriela Riscuta M.D., C.N.S., National Cancer Institute

Konstantin Salnikow Ph.D., National Cancer Institute


Useful Links:

Click here to subscribe to CAIG listserv

NIH corner ( restricted access for NIH people using their PIV card and password).


National Institute on Aginghttps://www.nia.nih.gov/research/labs


For information on Clinical Trials, please visit:

https://www.nia.nih.gov/research/clinical-trials


For information on the Baltimore Longitudinal Study of Aging (BLSA), please visit:

https://www.nia.nih.gov/research/labs/blsa/join-blsa


If interested in participating in a clinical trial, please contact the NIA recruitment line at 410-350-3941 or email NIAStudiesRecruitment@mail.nih.gov






                                       

                                                                         

Up-coming conference                                                              Registration   

Age-Dependent Changes in Cancer Biology

 October 26-27, 2020

Virtual Conference

The conference is organized in collaboration of National Cancer Institute, National Institute on Aging and National Institute of Environmental Health Sciences. It was announced for an in-person meeting ( April 2-3, 2020) and it is being rescheduled to a virtual meeting due to COVID-19. 

Draft Agenda

Day 1, October 26, 2020

Adjourn

10:00 am – 10:05 am

 Introduction and Overview

Gabriela Riscuta NCI

10:05 am -10:20 am

Opening Remarks: Ned Sharpless NCI

10:20 am - 10:35 am

Opening Remarks: Richard Hodes NIA, M.D., NIA

10:35 am -11:05 am

Keynote Speaker: Luigi Ferrucci, NIA, M.D., Ph.D., NIA/IRP

11:05 am - 11:45 am


Understanding the Molecular Biology of Cancer in Elderly

Moderator: Max Guo NIA

11:05 am -11:25 am

Anticancer mechanisms in long-lived mammals   

Vera Gorbunova (University of Rochester) (DAB/NIA)

11:25 am -11:45 am

Connecting cancer to aging – an evolutionary perspective

James V. Degregori (University of Colorado) (DAB/NIA)

11:45 am -12:05 pm

Panel Discussion

12: 05 pm - 12:25 pm

Lunch

12: 25 pm - 1:05 pm


12:25 pm-12:45 pm



12: 45 pm -1:05 pm

Cellular Senescence in Cancer and Aging

Moderator: Basil Eldadah, M.D., Ph.D., NIA

Mechanisms of immunosenescence and Immune response to vaccines in elderly  

Nan-Ping Weng, M.D., Ph.D., (Laboratory of Molecular Biology and Immunology, LMBI, NIA/IRP)

Cellular senescence in aging and cancer

Darren Baker, Ph.D. (Mayo Clinic)

1:05 pm – 1:25 pm

Panel Discussion

1:25 pm - 2:05 pm


1: 25 pm - 1: 45 pm


1:45 pm – 2:05 pm

 

Implication of Oxidative Stress Towards Cancer Biology

Moderator: Konstantin Salnikow, NCI1: 25 pm - 1: 45 pm, Ph.D., NCI

Gender effects in cancer and aging 

Vadim Gladyshev (Brigham and Women’s Hospital, Harvard Medical School)1:45 pm – 2:05 pm

Dysregulation of iron metabolism in cancer and aging  

Suzy Torti (University of Connecticut)

2:05 pm - 2:25 pm

Panel Discussion

2: 25 pm - 2:30 pm

Coffee break

2:30 pm – 3:10 pm


2:30 pm - 2:50 pm


2:50 pm - 3:10 pm


Senescence, Immune Response and Cancer in the Elderly

Moderators: Matt Young and Anil Wali, NCI

Telomere and genome integrity in cancer and aging  

Patricia Opresko University of Pittsburgh (NCI)

Inter-relationship between microbiota diversity, obesity and race in endometrial cancer

Victoria Lin Bae-Jump  (University of North Carolina, Chapel Hill)

3: 10 pm - 3: 30 pm

Panel Discussion

3: 30 pm - 4: 30 pm


3: 30 pm - 3:50 pm


3:50 pm - 4:10 pm

Environmental Factors: the Overlap of Carcinogens/Gerontogens

Moderator: Les Reinlib  NIEHS

Environmental genomics of breast and prostate cancer  

Susan Neuhausen (City of Hope) ( NIEHS)

 Breast Cancer in young & older women

Lead, Carolina Breast Cancer Study; co-I, African American Breast Cancer Epidemiology and Risk (AMBER); Cancer Genome Atlas Melissa Troester, UNC CH (NIEHS)

4:10 pm - 4:30 pm

Panel Discussion

 4:30 pm Adjourn


Day 2, October 27, 2020

10:00 am - 10: 10 am

Goals and Objectives

Konstantin Salnikow Ph.D. NCI

10:10 am - 10:40 am

Keynote: Epigenetic linkage of aging, cancer and nutrition

Trygve Tollefsbol (University of Alabama) (DCP/NCI)

10:40 am - 11:50 am


10:40 am - 11:00 am


11:00 am - 11:20 am


11:20 am - 11:50 am


Potential Impact of Nutrition on Cancer Prevention

Moderator Moderator: Gabriela Riscuta and Pat Prasanna, NCI

10:40 am -11:00 am

 

Senolytic bioactive food components and their biological pathway for action  

Simmin Meydani (Tufts University)  (DCP/NCI) 

11:00 am - 11:20 am

Cancer prevention in elderly and particularities for mechanisms of action  

Chengguo Xing  (University of Florida) (DCP/NCI)

11:20 am - 11:50 am

The mechanisms of fasting and advanced glycation end products in cancer prevention in elderly

Sebastian Brandhorst (University of Southern California) (DCP/NCI)

11:50 am -12:10 pm

Panel Discussion

12:10 pm - 12:30 pm

Lunch  Break

12:30 pm - 1:00 pm

Keynote speaker:  Jan Van Duersen (Mayo Clinic)

1:00 pm - 2:00 pm


Cancer Therapeutics and Treatment Optimization for the Elderly

Moderators: Weiwei Chen and Christina Liu, NCI

1:00 pm - 1:20 pm

 

Improvement of cancer therapy by exploiting cellular senescence

Judith  Judith Campisi  (Buck Institute for Research on Aging) (DCTD/NCI)  

1:20 pm - 1:40 pm

The development of AI-enhanced cardiac MRI to address cardiotoxicity in elderly Multiple Myeloma patients

Greg Lanza (Washington University at St. Louis) ( NCI/DCTD)

1:40 pm - 2:00 pm


Treatment Optimization for the elderly with comorbidities

Heidi Klepin (Wake Forest) (NCI/DCTD)

2:00 pm - 2: 20 pm

Panel Discussion

2:20 pm - 2:30 pm

Wrap Up and Adjourn



Planning Committee:

Luigi Ferrucci (NIA) Chair


Gabriela Riscuta (NCI/DCP); co-chair

Konstantin Salnikow (NCI/DCB); co-chair


Nelson Aguila (NIH/NCI)

Weiwei Chen (NIH/NCI)

Basil Eldadah ( NIA)

Max Guo (NIH/NIA/ERP)

Christina Liu (NIH/NCI)

Pat Prasana ( NIH/NCI/DCTD)

Leslie Reinlib (NIH/NIEHS)

Sudhir Srivastava (NIH/NCI/DCP)

Anil Wali (NIH/NCI)

Matthew Young (NIH/NCI/DCP)

 

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