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Co-chairs
Gabriela Riscuta: gabriela.riscuta@nih.gov
Konstantin Salnikow: salnikok@mail.nih.gov
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Up-coming conference Registration
POSTPONED
Age-Dependent Changes in Cancer Biology
April 2-3, 2020 ▪
The Natcher Center ▪
Bethesda, MD
Draft Agenda
Day 1, April 2, 2020
8:00 am - 8:30 am | Registration |
8:30 am – 8:40 am | Introduction and Overview Gabriela Riscuta M.D., NCI |
8:40-8:55 | Opening Remarks: Ned Sharpless M.D., NCI |
8:55-9:10 | Opening Remarks: Richard Hodes M.D., NCI |
9:10 am -9:40 am | Keynote Speaker: Luigi Ferrucci, M.D., Ph.D. NIA |
9:40 am - 11:30 am | Understanding the Molecular Biology of Cancer in Elderly Moderator: Max Guo |
9:40-10:00 | Anticancer mechanisms in long-lived mammals Vera Gorbunova (University of Rochester) (DAB/NIA) |
10:00-10:20 | Connecting cancer to aging – an evolutionary perspective James V. Degregori (University of Colorado) (DAB/NIA) |
10:20-10:30 | Coffee break |
10:30 am - 11:50 am 10:30-10:50 10:50-11:10 | Cellular Senescence in Cancer and Aging Moderator: Basil Eldadah, NIA Mechanisms of immunosenescence and Immune response to vaccines in elderly Nan-Ping Weng (Laboratory of Molecular Biology and Immunology, LMBI, NIA-IRP) Cellular senescence in aging and cancer. Darren Backer (Majo Clinic) |
11:10-11:30 | The differences in response to CART-T cell therapy in young versus old persons Carl June (University of Pennsylvania)
|
11:30 am - 11:50 am | Panel Discussion |
11:50 pm - 12:50 pm | Lunch |
12:50 pm - 1:50 pm
| Implication of Oxidative Stress Towards Cancer Biology Moderator: Konstantin Salnikow, DCB/NCI |
12:50-1:10 | Oxidative stress in cancer and aging Toren Finkel (Aging Institute, University of Pittsburgh) |
1:10-1:30 | Gender effects in cancer and aging Vadim Gladyshev (Brigham and Women’s Hospital, Harvard Medical School) |
1:30-1:50 | Dysregulation of iron metabolism in cancer and aging Suzy Torti (University of Connecticut) |
1:50 pm - 2:10 pm | Coffee break |
2:10 pm - 4:00pm
| Senescence, Immune Response and Cancer in the Elderly Moderator: Matt Young and Anil Wali (DCP/NCI) |
2:30-2:50 | Metabolites: effects on cancer and aging Fred Stevens (Linus Pauling Institute) |
2:50-3:10
| New technologies to study mitochondria-telomere cross-talk Ben van Houte |
3:10-3:30 3:30-3:50 | Inter-relationship between microbiota diversity, obesity and race in endometrial cancer Victoria Lin Bae-Jump (University of North Carolina, Chapel Hill) Cancer drug discovery by targeting aged tumor microenvironment Ashani Weeraratna (Johns Hopkins University) (DCTD/NCI) |
3:50 pm - 4:10 pm | Panel Discussion |
4:10 pm – 4:20 pm | Coffee Break |
4:20 pm - 5:20 pm 3:40-4:00 Pm 4:00-4:20pm | Environmental Factors: the Overlap of Carcinogens/Gerontogens Moderator: Nicole McNeil Ford and Les Reinlib Environmental genomics of breast and prostate cancer Susan Neuhausen (City of Hope) ( NIEHS)
Breast Cancer in young & older women; Lead, Carolina Breast Cancer Study; co-I, African American Breast Cancer Epidemiology and Risk (AMBER); Cancer Genome Atlas Melissa Troester, UNC CH (NIEHS) |
4:20-4:50 | Exploring Social Networks and Social Capital for Cancer Screening among Minorities in Public Housing Jamilia Sly (Icahn School of Medicine, Mt. Sinai) |
4:50 pm - 5:20 pm | Panel Discussion |
5:20 pm | Day 1 Wrap-Up |
Day 2, April 3, 2020
7:30-8:00am | Registration |
8:00 am - 8: 10 am | Goals and Objectives Konstantin Salnikow |
8:10 am - 8:50 am | Keynote: Epigenetic linkage of aging, cancer and nutrition Trygve Tollefsbol D.O., Ph.D., University of Alabama |
8:50 am - 9:50 am | Potential Impact of Nutrition on Cancer Prevention Moderator : Pataje Prasanna Ph.D., and Gabriela Riscuta M.D., NCI |
8:50-9:10
| Simmin Meydani D.V.M., Ph.D. Tufts University, MA Potential Impact of bioactive food components on cancer in the aged
|
9:10-9:30 | The mechanisms of fasting and advanced glycation end products in cancer prevention in elderly Sebastian Brandhorst Ph.D., University of Southern California, CA
|
9:30-9:50 | Cancer prevention in elderly and particularities for mechanisms of action Chengguo Xing Ph.D., University of Florida |
9:50 am -10:20 am | Panel Discussion |
10:20-10:30am | Coffee Break |
10:30-11:00 | Keynote speaker: Jan Van Duersen (Mayo Clinic) |
11:00 am - 12:00 am | Cancer Therapeutics and Treatment Optimization for the Elderly Moderators: Weiwei Chen and Christina Liu |
11:00-11:20
| Improvement of cancer therapy by exploiting cellular senescence Judith Campisi (Buck Institute for Research on Aging) (DCTD/NCI) |
11:20-11:40 | Targeting senescent cells using nanoparticles ΙGreg Lanza (Washington University at St. Louis) (DCTD/NCI) |
11:40-12:00 | Treatment Optimization and immunotherapy for the eldelrly with comorbidities Heidi Klepin (Wake Forest) (DCTD/NC) |
12:00 am - 12:30 pm | Panel Discussion |
12:30-12:40 pm | Wrap Up and Adjourn |
Planning Committee
Gabriela Riscuta (NCI/DCP); co-chair
Konstantin Salnikow (NCI/DCB); co-chair
Nelson Aguila (NIH/NCI)
Audie Atienza (NIH/NIA/ERP)
Weiwei Chen (NIH/NCI)
Rafael deCabo (NIH/NIA/IRP)
Myriam Gorospe (NIH/NIA/IRP)
Max Guo (NIH/NIA/ERP)
Christina Liu (NIH/NCI)
Nicole McNeil Ford (NIH/NCI)
Carmen Moten (NIH/NIA/ERP)
Pat Prasana ( NIH/NCI/DCTD)
Leslie Reinlib (NIH/NIEHS)
Ranjan Sen (NIH/NIA/IRP)
Harold Seifried ( NIH/NCI/DCP)
Sudhir Srivastava (NIH/NCI/DCP)
Anil Wali (NIH/NCI)
Matthew Young (NIH/NCI/DCP)
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