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Since 1997, EVS has worked with many partners to build shared content and services, so that information can be effectively exchanged, interpreted and analyzed while minimizing overall effort and cost.  Much of this content has been created and published using NCI Thesaurus and NCI Metathesaurus, as outlined below and described in more detail in the individual user profiles later, where other shared development efforts are also described.

NCI Thesaurus (NCIt)

NCI Thesaurus (NCIt) is NCI's core reference terminology. Over the last 10 years, it has also been adopted by FDA, CDISC, NCPDP and other partners as a shared standards development and coding environment, allowing participants to compare and harmonize with each other's content while taking advantage of full-text definitions, codes, and other features.

About 40,000 out of the over 90,000 current NCIt concepts have terms from both EVS and from one or more of these other sources. The chart below gives a detailed breakdown of the main areas of overlapping tagged content. Note that some partners have used NCI terms rather than tagging their own, so these figures understate the true extent of cross-source sharing.

NCIt concepts with terms from tagged outside sources (11.09d: September 2011)
Chart showing NCIt concepts with terms from tagged outside sources (11.09d: September 2011)

NCIt concepts with tagged synonyms from each outside source (13.03d: March 2013)

NCIt Concepts

Source

Unknown macro: {align} 335

BIOCARTA

Unknown macro: {align} 1,149

BRIDG

Unknown macro: {align} 27

CADSR

Unknown macro: {align} 921

CDC

Unknown macro: {align} 9,003

CDISC

Unknown macro: {align} 425

CRCH

Unknown macro: {align} 6,368

CTCAE

Unknown macro: {align} 4,421

CTRM

Unknown macro: {align} 903

DCP

Unknown macro: {align} 114

DICOM

Unknown macro: {align} 695

DTP

Unknown macro: {align} 16,334

FDA

Unknown macro: {align} 126

HL7

Unknown macro: {align} 215

ICH

Unknown macro: {align} 156

JAX

Unknown macro: {align} 255

KEGG

Unknown macro: {align} 4

NCICB

Unknown macro: {align} 5,154

NCI-GLOSS

Unknown macro: {align} 517

NCPDP

Unknown macro: {align} 1731

NICHD

Unknown macro: {align} 169

PID

Unknown macro: {align} 311

RENI

Unknown macro: {align} 62

SEER

Unknown macro: {align} 288

UCUM

Unknown macro: {align} 25

ZFin

NCI Metathesaurus (NCIm)

NCI Metathesaurus (NCIm) was started in the late 1990s to gather up, translate between, and publish the many terminologies used by NCI, including some created in part or whole within NCI. Development of NCI Thesaurus started within NCIm as NewPDQ, an effort to extend and restructure the PDQ Terminology long used to code cancer clinical trial, research and public information resources. NCIm continues to provide a vital environment for EVS collaboration with NCI and other partners to develop, map and publish terminologies of shared interest, and responds to the requirements of a broad range of stakeholders within the cancer research and biomedical community.

NCIt tagged content from outside sources is imported into NCIm with separate source tags. NCIt-derived sources are grouped separately below. The NCIm tags are mostly identical or very similar to those in NCIt; exceptions are CADSR, converted to NCI; HL7, converted to NCI-HL7; and CTRM, which is not imported.

NCIm sources and the number of concepts to which each contributes (201105: May 2011)

NCIm concepts

Source Label - NCIt-derived

Source Name

Unknown macro: {align} 334

BioC

BioCarta online maps of molecular pathways, adapted for NCI use, 1105E

Unknown macro: {align} 1,139

BRIDG

Biomedical Research Integrated Domain Group Model, 1105E

Unknown macro: {align} 921

CDC

U.S. Centers for Disease Control and Prevention, 1105E

Unknown macro: {align} 5,636

CDISC

Clinical Data Interchange Standards Consortium, 1105E

Unknown macro: {align} 406

CRCH

Cancer Research Center of Hawaii Nutrition Terminology, 1105E

Unknown macro: {align} 6,368

CTCAE

Common Terminology Criteria for Adverse Events, 1105E

Unknown macro: {align} 903

DCP

NCI Division of Cancer Prevention Program, 1105E

Unknown macro: {align} 114

DICOM

Digital Imaging Communications in Medicine, 1105E

Unknown macro: {align} 693

DTP

NCI Developmental Therapeutics Program, 1105E

Unknown macro: {align} 15,471

FDA

U.S. Food and Drug Administration, 1105E

Unknown macro: {align} 215

ICH

International Conference on Harmonization, 1105E

Unknown macro: {align} 156

JAX

Jackson Laboratories Mouse Terminology, adapted for NCI use, 1105E

Unknown macro: {align} 244

KEGG

KEGG Pathway Database, 1105E

Unknown macro: {align} 85,314

NCI

National Cancer Institute Thesaurus, 2011_05E

Unknown macro: {align} 5,084

NCI-GLOSS

NCI Dictionary of Cancer Terms, 1105E

Unknown macro: {align} 125

NCI-HL7

NCI Health Level 7, 1105E

Unknown macro: {align} 514

NCPDP

National Council for Prescription Drug Programs, 1105E

Unknown macro: {align} 715

NICHD

National Institute of Child Health and Human Development, 1105E

Unknown macro: {align} 169

PID

National Cancer Institute Nature Pathway Interaction Database, 1105E

Unknown macro: {align} 310

RENI

Registry Nomenclature Information System, 1105E

Unknown macro: {align} 287

UCUM

Unified Code for Units of Measure, 1105E

Unknown macro: {align} 25

ZFIN

Zebrafish Model Organism Database, 1105E


NCIm concepts

Source Label - Other

Source Name

Unknown macro: {align} 15,870

AOD

Alcohol and Other Drug Thesaurus, 2000

Unknown macro: {align} 278

AOT

Authorized Osteopathic Thesaurus, 2003

Unknown macro: {align} 13,255

CBO

Clinical Bioinformatics Ontology, 2011_02

Unknown macro: {align} 1,104

CCS

Clinical Classifications Software, 2005

Unknown macro: {align} 3,073

COSTAR

COSTAR, 1989-1995

Unknown macro: {align} 16,572

CSP

CRISP Thesaurus, 2006

Unknown macro: {align} 3,836

CST

COSTART, 1995

Unknown macro: {align} 345

CTEP

Cancer Therapy Evaluation Program, 2004

Unknown macro: {align} 7,278

DXP

DXplain, 1994

Unknown macro: {align} 77,923

FMA

Foundational Model of Anatomy Ontology, 2_0

Unknown macro: {align} 54,439

GO

Gene Ontology, 2010_04_01

Unknown macro: {align} 5,602

HCPCS

Healthcare Common Procedure Coding System, 2010

Unknown macro: {align} 7,483

HL7V3.0

HL7 Vocabulary Version 3.0, 2006_05

Unknown macro: {align} 29,335

HUGO

HUGO Gene Nomenclature, 2010_05

Unknown macro: {align} 11,532

ICD10

ICD10, 1998

Unknown macro: {align} 1,004

ICD10AE

ICD10, American English Equivalents, 1998

Unknown macro: {align} 97,631

ICD10CM

International Classification of Diseases, 10th Edition, Clinical Modification, 2010_03

Unknown macro: {align} 181,116

ICD10PCS

ICD-10-PCS, 2009

Unknown macro: {align} 20,779

ICD9CM

International Classification of Diseases, Ninth Revision, Clinical Modification, 2011

Unknown macro: {align} 2,466

ICDO

International Classification of Diseases for Oncology, 3rd Edition, 2000

Unknown macro: {align} 748

ICPC

International Classification of Primary Care, 1993

Unknown macro: {align} 37,923

ICPC2ICD10ENG

ICPC2 - ICD10 Thesaurus, 200412

Unknown macro: {align} 80,206

LNC

Logical Observation Identifier Names and Codes, 232

Unknown macro: {align} 41

MCM

McMaster University Epidemiology Terms, 1992

Unknown macro: {align} 331

MDBCAC

Mitelman Database of Chromosome Aberrations in Cancer, 2005_12

Unknown macro: {align} 47,210

MDR

Medical Dictionary for Regulatory Activities Terminology, 14.0

Unknown macro: {align} 1,897

MEDLINEPLUS

MedlinePlus Health Topics, 20080614

Unknown macro: {align} 900

MGED

MGED Ontology, 131

Unknown macro: {align} 310,485

MSH

Medical Subject Headings, 2011_2010_08_30

Unknown macro: {align} 85,138

MTH

UMLS Metathesaurus, 2010AB

Unknown macro: {align} 19,880

MTHFDA

Metathesaurus FDA National Drug Code Directory, 2010_08_02

Unknown macro: {align} 337

MTHHH

Metathesaurus HCPCS Hierarchical Terms, 2010

Unknown macro: {align} 16,081

MTHICD9

International Classification of Diseases, Ninth Revision, Clinical Modification, Metathesaurus additional entry terms, 2011

Unknown macro: {align} 94

MTHICPC2ICD107B

ICPC2 - ICD10 Thesaurus, 7-bit Equivalents, 0412

Unknown macro: {align} 76

MTHICPC2ICD10AE

ICPC2 - ICD10 Thesaurus, American English Equivalents, 0412

Unknown macro: {align} 1,633

MTHMST

Metathesaurus Version of Minimal Standard Terminology Digestive Endoscopy, 2001

Unknown macro: {align} 12,969

MTHSPL

Metathesaurus FDA Structured Product Labels, 2010_08_27

Unknown macro: {align} 478,187

NCBI

NCBI Taxonomy, 2010_04_29

Unknown macro: {align} 135

NCIMTH

NCI Metathesaurus

Unknown macro: {align} 38,863

NDFRT

National Drug File, 2010_09_07

Unknown macro: {align} 1,781

NPO

NPO: NanoParticle Ontology for Cancer Nanotechnology Research, 2010_10_31

Unknown macro: {align} 63,924

OMIM

Online Mendelian Inheritance in Man, 2010_04_08

Unknown macro: {align} 9,869

PDQ

Physician Data Query, 2010_08_06

Unknown macro: {align} 2,041

PMA

Portfolio Management Application, 2010

Unknown macro: {align} 268

PNDS

Perioperative Nursing Data Set, 2nd edition, 2002

Unknown macro: {align} 940

QMR

Quick Medical Reference (QMR), 1996

Unknown macro: {align} 30,033

RADLEX

RadLex, 3_33

Unknown macro: {align} 227,498

RXNORM

RxNorm Vocabulary, 10AA_100907F

Unknown macro: {align} 281,843

SNOMEDCT

SNOMED Clinical Terms

Unknown macro: {align} 4,808

SPN

Standard Product Nomenclature, 2003

Unknown macro: {align} 156

SRC

Metathesaurus Source Terminology Names

Unknown macro: {align} 13,788

UMD

UMDNS: product category thesaurus, 2010

Unknown macro: {align} 1,765

USPMG

USP Model Guidelines, 2004

Unknown macro: {align} 61,191

UWDA

University of Washington Digital Anatomist, 1.7.3

Unknown macro: {align} 26,546

VANDF

Veterans Health Administration National Drug File, 2010_07_26

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