NCI-60 Growth Inhibition Data

Full release of endpoints calculated from concentration curves.

A description of the NCI-60 assay and calculations can be found  here.

Please note the links for more information on the SNB-19, U251, NCI/ADR-RES, and MDA-MB-435 cell lines.

• MDA-MB-435
• U251
• SNB-19
• NCI/ADR-RES

File Format is comma delimited with the following fields:

 

• NSC number - the NCI's internal ID number
• Concentration Unit - Either M for molar or u for µ g/ml
• log of the highest concentration tested
• panel name for the cell line
• cell line name
• panel number of the cell line 
• cell number of the cell line 
• -log of the result (GI₅₀, TGI, LC₅₀ depending on the file)
• number of tests for this NSC and cell line
• maximum number of tests for this NSC
• StdDev Standard Deviation of the Log₁₀ of the results averaged across all tests for this NSC and cell line

Sept 2014 Release

GI50 Data (Sept 2014)

TGI data (Sept 2014)

LC50 Data (Sept 2014)

Sept 2012 Release

GI50 Data (Sept 2012)

TGI Data (Sept 2012)

LC50 Data (Sept 2012)

 

Full dose response data.

For positive controls, averaged data is given.

File Format is comma delimited with the following fields:

 

• NSC number - the NCI's internal ID number
• Concentration Unit - Either M for molar or u for µ g/ml
• log of the concentration tested
• panel name for the cell line
• cell line name
• panel number of the cell line 
• cell number of the cell line 
• GIPCRNT       100 is control growth, 0 is complete inhibition of growth (cytostatic), and -100 is complete cell kill
  
  

DOSE_RESPONSE (Sept 2014)

DOSE_RESPONSE_MANY (Sept 2014)

 

Sept 2012 release

CANCER60_DOSE_RESPONSE (Sept 2012)

DOSE_RESPONSE_MANY_(Sept 2012)

 

One Dose Data

One Dose Data (Sept 2014)

One_Dose_Data_(Sept 2012)

 

Data for Diversity Set

GI_50_Data_Diversity_Set (August 1999)

TGI_Data_Diversity_Set (August 1999)

LC_50_Data_Diversity_Set (August 1999)