2021-01-19 Best Practices Monthly Meeting notes

• Todd to send out link to current Best Practices Doc
• Todd to reach out to Alison Heath about Seven Bridges coordination

• Did get comments back
• Will and Heather finalizing document
• Wrapping up into a final recommendation
• Jeff to organize the final meeting

No updates

Waiting on datasets from lymphoma

Estimate for an April delivery

Cohort 1 curated, waiting for final results from pipeline update, working on rest of cohorts

About 35 patients WGS, RNASeq, subset will have IO, 3 time points

Can ICDC pull directly from Redcap?  No, we don't have that capability

• Use Redcap for all clinical trials
• Widely distributed
• CHOP may be connecting via Seven Bridges
• ICDC team to investigate, Cheryl has someone who can help
• IO data should go in when ready, is standardized.  Flow and IHC may not have sufficient standards
  • Nano for now, will consider Flow and IHC later
• Enough in IO and clin/path to proceed with those
  • Having connection to Redcap would make this easier
  • Can use Excel for now
  • ICDC data model currently may not match what is needed
  • Standardizing how IO data is reported is part of why it should be in a database
  • Clin/path is in the same situation
    • Intent is to have a standardize clin/path set across all patients
• There was an intent to also influence data collection in a more standardized way

• Glioma released at TCIA
• Nothing else on horizon
• Need to look at upcoming trials for path or other images
• DOI points to data
• ICDC has a task to integrate images and point to TCIA

• Metadata received for MCG01
• Connecting with Dr. Milner on osteosarcoma/melanoma vaccine trial

• COTC Standard of care data is close to ready
  • 90 day embargo
  • Clinical trial as a comparative for other model trials
  • Very robust information on cases
  • Excel spreadsheet currently