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Since 1997, EVS has worked with many partners to build shared content and services, so that information can be effectively exchanged, interpreted and analyzed while minimizing overall effort and cost.  Much of this content has been created and published using NCI Thesaurus and NCI Metathesaurus, as outlined below and described in more detail in the individual user profiles later, where other shared development efforts are also described.

NCI Thesaurus (NCIt)

NCI Thesaurus (NCIt) is NCI's core reference terminology. Over the last 10 years, it has also been adopted by FDA, CDISC, NCPDP and other partners as a shared standards development and coding environment, allowing participants to compare and harmonize with each other's content while taking advantage of full-text definitions, codes, and other features.

About 40,000 out of the nearly 100,000 current NCIt concepts have terms from both EVS and from one or more of these other sources. The chart below gives the last available detailed breakdown, for June 2010. Note that some partners have used NCI terms rather than tagging their own, so these figures understate the true extent of cross-source sharing.

NCIt concepts with terms from tagged outside sources (11.09d: September 2011)

NCIt concepts with tagged synonyms from each outside source (11.09d: September 2011)

Source

NCIt Concepts

BIOCARTA

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335

BRIDG

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1,139

CADSR

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27

CDC

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919

CDISC

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5,633

CRCH

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424

CTCAE

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6,368

CTRM

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4,421

DCP

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902

DICOM

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114

DTP

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697

FDA

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15,772

HL7

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125

ICH

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215

JAX

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156

KEGG

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255

NCICB

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4

NCI-GLOSS

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5,157

NCPDP

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515

NICHD

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886

PID

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169

RENI

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311

SEER

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62

UCUM

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287

ZFin

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25

NCI Metathesaurus (NCIm)

NCI Metathesaurus (NCIm) was started in the late 1990s to gather up, translate between, and publish the many terminologies used by NCI, including some created in part or whole within NCI. Development of NCI Thesaurus started within NCIm as NewPDQ, an effort to extend and restructure the PDQ Terminology long used to code cancer clinical trial, research and public information resources. NCIm continues to provide a vital environment for EVS collaboration with NCI and other partners to develop, map and publish terminologies of shared interest, and responds to the requirements of a broad range of stakeholders within the cancer research and biomedical community.

[details on NCIm collaborations and concept/term statistics pending]

NCIm sources and the number of concepts to which each contributes (201105: May 2011)

Number of concepts

Source Label

Source Name

15870

AOD

Alcohol and Other Drug Thesaurus, 2000

278

AOT

Authorized Osteopathic Thesaurus, 2003

334

BioC

BioCarta online maps of molecular pathways, adapted for NCI use, 1105E

1139

BRIDG

Biomedical Research Integrated Domain Group Model, 1105E

13255

CBO

Clinical Bioinformatics Ontology, 2011_02

1104

CCS

Clinical Classifications Software, 2005

921

CDC

U.S. Centers for Disease Control and Prevention, 1105E

5636

CDISC

Clinical Data Interchange Standards Consortium, 1105E

0

COH

City of Hope, 1105E

3073

COSTAR

COSTAR, 1989-1995

406

CRCH

Cancer Research Center of Hawaii Nutrition Terminology, 1105E

16572

CSP

CRISP Thesaurus, 2006

3836

CST

COSTART, 1995

6368

CTCAE

Common Terminology Criteria for Adverse Events, 1105E

345

CTEP

Cancer Therapy Evaluation Program, 2004

903

DCP

NCI Division of Cancer Prevention Program, 1105E

114

DICOM

Digital Imaging Communications in Medicine, 1105E

693

DTP

NCI Developmental Therapeutics Program, 1105E

7278

DXP

DXplain, 1994

15471

FDA

U.S. Food and Drug Administration, 1105E

77923

FMA

Foundational Model of Anatomy Ontology, 2_0

54439

GO

Gene Ontology, 2010_04_01

5602

HCPCS

Healthcare Common Procedure Coding System, 2010

7483

HL7V3.0

HL7 Vocabulary Version 3.0, 2006_05

29335

HUGO

HUGO Gene Nomenclature, 2010_05

11532

ICD10

ICD10, 1998

1004

ICD10AE

ICD10, American English Equivalents, 1998

97631

ICD10CM

International Classification of Diseases, 10th Edition, Clinical Modification, 2010_03

181116

ICD10PCS

ICD-10-PCS, 2009

20779

ICD9CM

International Classification of Diseases, Ninth Revision, Clinical Modification, 2011

2466

ICDO

International Classification of Diseases for Oncology, 3rd Edition, 2000

215

ICH

International Conference on Harmonization, 1105E

748

ICPC

International Classification of Primary Care, 1993

37923

ICPC2ICD10ENG

ICPC2 - ICD10 Thesaurus, 200412

156

JAX

Jackson Laboratories Mouse Terminology, adapted for NCI use, 1105E

244

KEGG

KEGG Pathway Database, 1105E

80206

LNC

Logical Observation Identifier Names and Codes, 232

41

MCM

McMaster University Epidemiology Terms, 1992

331

MDBCAC

Mitelman Database of Chromosome Aberrations in Cancer, 2005_12

47210

MDR

Medical Dictionary for Regulatory Activities Terminology, 14.0

1897

MEDLINEPLUS

MedlinePlus Health Topics, 20080614

900

MGED

MGED Ontology, 131

310485

MSH

Medical Subject Headings, 2011_2010_08_30

85138

MTH

UMLS Metathesaurus, 2010AB

19880

MTHFDA

Metathesaurus FDA National Drug Code Directory, 2010_08_02

337

MTHHH

Metathesaurus HCPCS Hierarchical Terms, 2010

16081

MTHICD9

International Classification of Diseases, Ninth Revision, Clinical Modification, Metathesaurus additional entry terms, 2011

94

MTHICPC2ICD107B

ICPC2 - ICD10 Thesaurus, 7-bit Equivalents, 0412

76

MTHICPC2ICD10AE

ICPC2 - ICD10 Thesaurus, American English Equivalents, 0412

1633

MTHMST

Metathesaurus Version of Minimal Standard Terminology Digestive Endoscopy, 2001

12969

MTHSPL

Metathesaurus FDA Structured Product Labels, 2010_08_27

478187

NCBI

NCBI Taxonomy, 2010_04_29

85314

NCI

National Cancer Institute Thesaurus, 2011_05E

5084

NCI-GLOSS

NCI Dictionary of Cancer Terms, 1105E

125

NCI-HL7

NCI Health Level 7, 1105E

135

NCIMTH

NCI Metathesaurus

0

NCISEER

NCI SEER ICD Neoplasm Code Mappings, 1999

514

NCPDP

National Council for Prescription Drug Programs, 1105E

38863

NDFRT

National Drug File, 2010_09_07

715

NICHD

National Institute of Child Health and Human Development, 1105E

1781

NPO

NPO: NanoParticle Ontology for Cancer Nanotechnology Research, 2010_10_31

63924

OMIM

Online Mendelian Inheritance in Man, 2010_04_08

9869

PDQ

Physician Data Query, 2010_08_06

169

PID

National Cancer Institute Nature Pathway Interaction Database, 1105E

2041

PMA

Portfolio Management Application, 2010

268

PNDS

Perioperative Nursing Data Set, 2nd edition, 2002

940

QMR

Quick Medical Reference (QMR), 1996

30033

RADLEX

RadLex, 3_33

310

RENI

Registry Nomenclature Information System, 1105E

227498

RXNORM

RxNorm Vocabulary, 10AA_100907F

281843

SNOMEDCT

SNOMED Clinical Terms

4808

SPN

Standard Product Nomenclature, 2003

156

SRC

Metathesaurus Source Terminology Names

287

UCUM

Unified Code for Units of Measure, 1105E

13788

UMD

UMDNS: product category thesaurus, 2010

1765

USPMG

USP Model Guidelines, 2004

61191

UWDA

University of Washington Digital Anatomist, 1.7.3

26546

VANDF

Veterans Health Administration National Drug File, 2010_07_26

25

ZFIN

Zebrafish Model Organism Database, 1105E

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