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  1. Use of Vocabulary
    use of controlled vocabularies is necessary; species specific, computer processing (heart and Heart are not the same for a computer)
  2. EVS
    lack of terms, outdated terms, terms are specific to clinical use but not to research/animal research
  3. Unique Mouse identifier
    How to identify a mouse uniquely to enable linking of all data?
  4. Creation of DICOM header
    Use of DICOM header, how to create one, small animal imaging DICOM supplement
  5. Master "patient" index
    How to link all data together?
  6.  DICOM is not always prepared to capture mouse organs e.g. cleared fat pad.  Mouse to human organs to do always transfer.
  7.  DICOM Images – The challenge exists with the change that can happen between the original location---the transplant location---and the location that actually gets scanned.

  8. Trouble with XML annotation files to whole slide images via spectrum

  9. TCGA does not have any WSI’s of immunohistochemistry

  10. Brucker equipment DICOM does not contain the same fields as TCGA which makes the process dependent on Kirk Smith to attach appropriate fields.

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