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Product: caIntegrator
Version: 1.4.1
Date: October 2013

 

Contents of this Page

Introduction

caIntegrator is a web-based software package that allows researchers to set up custom, caBIG-compatible web portals to conduct integrative research, without requiring programming experience. These portals bring together heterogeneous clinical, microarray and medical imaging data to enrich multidisciplinary research.

Using caIntegrator, researchers can execute and save queries to identify and collect many types of data, combining clinical information with genetic and genomic data to enable multidimensional analysis. caintegrator uses caGrid analytical services such as GenePattern and BioConductor to perform analysis on the integrated study data, including clinical survival data.

Release History

  • caIntegrator2 v1.0.0 -- Oct 2009
  • caIntegrator2 v1.0.1 -- Jan 2010
  • caIntegrator2 v1.1.0 -- Jun 2010
  • caIntegrator v1.2.0 -- Sep 2010
  • caIntegrator v1.3.0 -- Jun 2011
  • caIntegrator v1.3.1 – Nov 2011
  • caIntegrator v1.4 -- July 2012
  • caIntegrator v1.4.1 – Oct 2013

Anticipated Releases

  • caIntegrator v1.4.2 - Jan 2014

Highlights of caIntegrator v1.4.1

  • Enhancements to the BioDBNet search: Users can now search for gene pathways by gene symbol, then select the gene pathways for which the search should return genes.  Users can also select whether or not searches should be case sensitive.
  • caIntegrator is now able to receive data from the AIM service at Emory.
  • Upgrade to Struts 2.3.15.1 to address a serious security vulnerability that allows attackers to gain administrative control of the server.
  • Technology upgrades: IGV 2.1.
  • Section 508 compliance improvements.

Features and Defects Addressed in this Release

For a complete list of changes in 1.4.1 refer to the Release Notes in JIRA.

Known Issues/Defects

  1. caIntegrator 1.4.1 can only pull array data from caArray v 2.5.1 and newer.
  2. CAINT-1070 Attempting to Add New Genomic Data Source in IE8 produces Restricted Area error
    Note: There is a workaround for this issue. After encountering the error, go to Manage Studies -> Edit Study page, and re-add the Genomic Data Source. See CAINT-1070.
  3. There is an issue that may be seen if a user attempts to install an older version of caIntegrator after installing caIntegrator 1.4.1 using the Windows GUI installer. Older versions of caIntegrator use JBoss 4 in the installation whereas caIntegrator 1.4.1 uses JBoss 5. To avoid the issue the user must delete the .installer-caintegrator2 file before beginning the second installation. The .installer-caintegrator2 file can usually be found in a default directory such as C:\Documents and Settings\username. If this file is not removed JBoss 5 will be installed instead of JBoss 4 and the installation will fail.
  4. There is a known issue within the UPT that account administrators may encounter when they add new users. The UPT may erroneously indicate that the user was already created and is a duplicate. When this happens and the user is not a duplicate the new user will be create as expected and the error message can be ignored. CSM-716, New user can be created in CSM 4.2.3 successfully, but the message displayed in browser is wrong. See CSM-716.
  5. There is a known issue in caIntegrator: Uploading large clinical files and then annotating the data takes longer than expected - i.e. the screen goes blank for a long time between selections.  See CAINT-73.  This is fixed in 1.4.2 by upgrading EhCache to 2.6.6 (see CAINT-1301).
  6. There is known issue on that occurs intermittently on NCI's STAGE tier where the user gets an "Unauthorized access" during study creation (see CAINT-1334).

See the JIRA tracker for existing open defects, community requests,resolutions and feature requests: https://tracker.nci.nih.gov/browse/CAINT

Bug Reports, Feature Requests, And Support

Send email to Application Support to request technical support.

To report a bug or request a new feature, refer to Report a defect or make a feature request for caIntegrator.

See the JIRA tracker for existing open defects, community requests,resolutions and feature requests: https://tracker.nci.nih.gov/browse/CAINT

Documentation and Files

Links to all documentation and files can be found on the caIntegrator Documentation wiki page.

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