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Exploring Investigation Details

AnchorexploringexploringYou can continue exploring investigation data by clicking a link to investigation, study, or assay details. Links to these details are on the Browse Investigations page or on the Search Investigations page, after you search on a keyword or phrase. These details

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counts of studies, assays, samples, and files. The metadata available for an investigation determines if other entities, such as sources and collections, are available for counts. From these details pages, you can visualize the structure of the investigation and download selected study files, download the full archive, and download only the metadata.

To explore investigation details

  1. Browse investigations or search investigations until you find an investigation, a study, or an assay in which you are interested.
    The search results appear.
    Example investigation as listed in search results.Image Removed

  2. Click the link corresponding with the investigation, study, or assay you are interested in exploring.
    The respective investigation details, study details, or assay details page appears.

  3. You can do the following from the details pages:

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Exploring Investigation Details
Exploring Investigation Details

Investigation Details Page

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Investigation Details Page
Investigation Details Page

Study Details Page

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Investigation Study Details PageInvestigation
Study Details Page

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Assay Details Page

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Assay Details Page
The study details page shows the investigation name at the top followed by a visualization of the investigation filename, study filename and number of samples in the study, and assay filename and number of files (and total file size) in the assay. Below the visualization are links to download all or part of the investigation, its identifier, and its description. All of the icons on the page are clickable links.
Study Details page.Image Removed
Assay Details Page

The assay details page shows the study name at the top followed by a visualization of the investigation filename, study filename and number of samples in the study, and assay filename and number of files (and total file size) in the assay. Below the visualization are links to download all or part of the assay, its file name, measurement type, and technology type. In the Visualize and Select section, the relationship of the study to its processes, and its processes to its files, are depicted in clickable icons. Click any icon to further filter the investigation data and download only a selected portion of it.

Visualizing and Filtering Data

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Assay Details pageImage Removed
Visualizing and Filtering Data

Once you browse or search the CSSI DCC data sets and reach a selected investigation details, study details, or assay details page, you can continue exploring the data. The ISA-Tab format is hierarchical, with investigation components becoming more granular as you proceed down the hierarchy. The largest organizing entity is the investigation, which holds one or more studies. Each study includes one or more assays. Assays are composed of samples, which in turn are composed of protocols. Data files are often associated with a protocol.

The following diagram depicts the hierarchy, without the samples and protocols.

Visualizing and Filtering Data

Visualizing and Filtering Investigations

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Structure of ISA data model as described in the text on this page.Image Removed
Visualizing and Filtering Investigations

The investigation details page shows icons that represent the relationship of the investigation to its studies and assays. In the case of PSON Cell Line Genomic Characterization - mRNA, the investigation has one study and one assay.
Investigation Details pageImage Removed

You cannot filter data currently at the investigation level any further in the CSSI DCC Portal. You can only download the investigation's full data at this point, or start exploring its studies and assays.

Selecting Multiple Objects

If any investigation has more than one study and assay, you can select which ones you want to filter by clicking the Select Multiple Objects box.

For example, the following investigation has many studies and assays, so it displays horizontally with a slider on the side to move up and down. It also has zoom out and zoom in buttons to see more or fewer objects.

Investigation with multiple studies and assaysImage Removed

Select the boxes next to the objects you want to visualize and filter. If you download these objects, all of these objects will be included in the download.

Visualizing and Filtering Study Data

If you select the study in the PSON Cell Line Genomic Characterization - mRNA investigation or arrive at any other Study Details page through a search, you can visualize the study's file structure and filter on any field.

You can also select multiple objects to visualize and filter within a single investigation.

To visualize and select study data

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An example Study Details page.Image Removed

In the Visualize and Select area, click one of the entities.

Info
titleStudy Hierarchy

The hierarchy of entities for studies according to the ISA-Tab standard is as follows, from less granular to more granular:

Source > Protocol > Sample

For example, click Source. Metadata for that source appears.

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Follow this same procedure if you want to filter on Protocol or Sample instead of Source.

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Visualizing and Filtering Investigations

Selecting Multiple Objects

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Selecting Multiple Objects
Selecting Multiple Objects

Visualizing and Filtering Study Data

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Visualizing and Filtering Study Data
Visualizing and Filtering Study Data

Visualizing and Filtering Assay Data

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Visualizing and Filtering Assay Data
Visualizing and Filtering Assay Data

Visualizing and Filtering Assay Data

If you select the assay in the PSON Cell Line Genomic Characterization - mRNA investigation or arrive at any other Assay Details page through a search, you can visualize the assay's file structure and filter on any field.

You can also select multiple objects to visualize and filter within a single investigation.

To visualize and select assay data

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A sample Assay Details page.Image Removed

In the Visualize and Select area, click one of the entities. Note that the width of some visualizations require you to scroll by clicking the arrows at the bottom of the page.

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titleAssay Hierarchy

The hierarchy of entities for assays according to the ISA-Tab standard is as follows, from less granular to more granular:

Sample > Protocol > Data File

For example, click the sample. Metadata for the sample appears.

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Follow this same procedure if you want to filter on protocol instead of sample.

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Click one or more values in the list to select them. To select multiple values, click one, wait for it to appear on the Metadata for Sample page, and then click the arrow again to select another value. To clear a selection, click that value again.
Metadata dialog box with selected sample names.Image Removed

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Some entities do not have associated metadata fields on which you can filter the study or assay. In that case, when you click the icon for that entity, you see a message letting you know that no metadata fields are available.

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Searching Investigation Data

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