Since 1997, EVS has worked with many partners to build shared content and services, so that information can be effectively exchanged, interpreted and analyzed while minimizing overall effort and cost. Much of this content has been created and published using NCI Thesaurus and NCI Metathesaurus, as outlined below and described in more detail in the individual user profiles later, where other shared development efforts are also described.
NCI Thesaurus (NCIt)
NCI Thesaurus (NCIt) is NCI's core reference terminology. Over the last 10 years, it has also been adopted by FDA, CDISC, NCPDP and other partners as a shared standards development and coding environment, allowing participants to compare and harmonize with each other's content while taking advantage of full-text definitions, codes, and other features.
About 40,000 out of the over 90,000 current NCIt concepts have terms from both EVS and from one or more of these other sources. The chart below gives a detailed breakdown of the main areas of overlapping tagged content. Note that some partners have used NCI terms rather than tagging their own, so these figures understate the true extent of cross-source sharing.
NCIt concepts with terms from tagged outside sources (11.09d: September 2011)
NCIt concepts with tagged synonyms from each outside source (11.09d: September 2011)
NCIt Concepts |
Source |
|---|---|
| Unknown macro: {align} 335 |
BIOCARTA |
| Unknown macro: {align} 1,139 |
BRIDG |
| Unknown macro: {align} 27 |
CADSR |
| Unknown macro: {align} 919 |
CDC |
| Unknown macro: {align} 5,633 |
CDISC |
| Unknown macro: {align} 424 |
CRCH |
| Unknown macro: {align} 6,368 |
CTCAE |
| Unknown macro: {align} 4,421 |
CTRM |
| Unknown macro: {align} 902 |
DCP |
| Unknown macro: {align} 114 |
DICOM |
| Unknown macro: {align} 697 |
DTP |
| Unknown macro: {align} 15,772 |
FDA |
| Unknown macro: {align} 125 |
HL7 |
| Unknown macro: {align} 215 |
ICH |
| Unknown macro: {align} 156 |
JAX |
| Unknown macro: {align} 255 |
KEGG |
| Unknown macro: {align} 4 |
NCICB |
| Unknown macro: {align} 5,157 |
NCI-GLOSS |
| Unknown macro: {align} 515 |
NCPDP |
| Unknown macro: {align} 886 |
NICHD |
| Unknown macro: {align} 169 |
PID |
| Unknown macro: {align} 311 |
RENI |
| Unknown macro: {align} 62 |
SEER |
| Unknown macro: {align} 287 |
UCUM |
| Unknown macro: {align} 25 |
ZFin |
NCI Metathesaurus (NCIm)
NCI Metathesaurus (NCIm) was started in the late 1990s to gather up, translate between, and publish the many terminologies used by NCI, including some created in part or whole within NCI. Development of NCI Thesaurus started within NCIm as NewPDQ, an effort to extend and restructure the PDQ Terminology long used to code cancer clinical trial, research and public information resources. NCIm continues to provide a vital environment for EVS collaboration with NCI and other partners to develop, map and publish terminologies of shared interest, and responds to the requirements of a broad range of stakeholders within the cancer research and biomedical community.
NCIt tagged content from outside sources is imported into NCIm with separate source tags. NCIt-derived sources are grouped separately below. The NCIm tags are mostly identical or very similar to those in NCIt; exceptions are CADSR, converted to NCI; HL7, converted to NCI-HL7; and CTRM, which is not imported.
NCIm sources and the number of concepts to which each contributes (201105: May 2011)
NCIm concepts |
Source Label - NCIt-derived |
Source Name |
|---|---|---|
| Unknown macro: {align} 334 |
BioC |
BioCarta online maps of molecular pathways, adapted for NCI use, 1105E |
| Unknown macro: {align} 1,139 |
BRIDG |
Biomedical Research Integrated Domain Group Model, 1105E |
| Unknown macro: {align} 921 |
CDC |
U.S. Centers for Disease Control and Prevention, 1105E |
| Unknown macro: {align} 5,636 |
CDISC |
Clinical Data Interchange Standards Consortium, 1105E |
| Unknown macro: {align} 406 |
CRCH |
Cancer Research Center of Hawaii Nutrition Terminology, 1105E |
| Unknown macro: {align} 6,368 |
CTCAE |
Common Terminology Criteria for Adverse Events, 1105E |
| Unknown macro: {align} 903 |
DCP |
NCI Division of Cancer Prevention Program, 1105E |
| Unknown macro: {align} 114 |
DICOM |
Digital Imaging Communications in Medicine, 1105E |
| Unknown macro: {align} 693 |
DTP |
NCI Developmental Therapeutics Program, 1105E |
| Unknown macro: {align} 15,471 |
FDA |
U.S. Food and Drug Administration, 1105E |
| Unknown macro: {align} 215 |
ICH |
International Conference on Harmonization, 1105E |
| Unknown macro: {align} 156 |
JAX |
Jackson Laboratories Mouse Terminology, adapted for NCI use, 1105E |
| Unknown macro: {align} 244 |
KEGG |
KEGG Pathway Database, 1105E |
| Unknown macro: {align} 85,314 |
NCI |
National Cancer Institute Thesaurus, 2011_05E |
| Unknown macro: {align} 5,084 |
NCI-GLOSS |
NCI Dictionary of Cancer Terms, 1105E |
| Unknown macro: {align} 125 |
NCI-HL7 |
NCI Health Level 7, 1105E |
| Unknown macro: {align} 514 |
NCPDP |
National Council for Prescription Drug Programs, 1105E |
| Unknown macro: {align} 715 |
NICHD |
National Institute of Child Health and Human Development, 1105E |
| Unknown macro: {align} 169 |
PID |
National Cancer Institute Nature Pathway Interaction Database, 1105E |
| Unknown macro: {align} 310 |
RENI |
Registry Nomenclature Information System, 1105E |
| Unknown macro: {align} 287 |
UCUM |
Unified Code for Units of Measure, 1105E |
| Unknown macro: {align} 25 |
ZFIN |
Zebrafish Model Organism Database, 1105E |
NCIm concepts |
Source Label - Other |
Source Name |
|---|---|---|
| Unknown macro: {align} 15,870 |
AOD |
Alcohol and Other Drug Thesaurus, 2000 |
| Unknown macro: {align} 278 |
AOT |
Authorized Osteopathic Thesaurus, 2003 |
| Unknown macro: {align} 13,255 |
CBO |
Clinical Bioinformatics Ontology, 2011_02 |
| Unknown macro: {align} 1,104 |
CCS |
Clinical Classifications Software, 2005 |
| Unknown macro: {align} 3,073 |
COSTAR |
COSTAR, 1989-1995 |
| Unknown macro: {align} 16,572 |
CSP |
CRISP Thesaurus, 2006 |
| Unknown macro: {align} 3,836 |
CST |
COSTART, 1995 |
| Unknown macro: {align} 345 |
CTEP |
Cancer Therapy Evaluation Program, 2004 |
| Unknown macro: {align} 7,278 |
DXP |
DXplain, 1994 |
| Unknown macro: {align} 77,923 |
FMA |
Foundational Model of Anatomy Ontology, 2_0 |
| Unknown macro: {align} 54,439 |
GO |
Gene Ontology, 2010_04_01 |
| Unknown macro: {align} 5,602 |
HCPCS |
Healthcare Common Procedure Coding System, 2010 |
| Unknown macro: {align} 7,483 |
HL7V3.0 |
HL7 Vocabulary Version 3.0, 2006_05 |
| Unknown macro: {align} 29,335 |
HUGO |
HUGO Gene Nomenclature, 2010_05 |
| Unknown macro: {align} 11,532 |
ICD10 |
ICD10, 1998 |
| Unknown macro: {align} 1,004 |
ICD10AE |
ICD10, American English Equivalents, 1998 |
| Unknown macro: {align} 97,631 |
ICD10CM |
International Classification of Diseases, 10th Edition, Clinical Modification, 2010_03 |
| Unknown macro: {align} 181,116 |
ICD10PCS |
ICD-10-PCS, 2009 |
| Unknown macro: {align} 20,779 |
ICD9CM |
International Classification of Diseases, Ninth Revision, Clinical Modification, 2011 |
| Unknown macro: {align} 2,466 |
ICDO |
International Classification of Diseases for Oncology, 3rd Edition, 2000 |
| Unknown macro: {align} 748 |
ICPC |
International Classification of Primary Care, 1993 |
| Unknown macro: {align} 37,923 |
ICPC2ICD10ENG |
ICPC2 - ICD10 Thesaurus, 200412 |
| Unknown macro: {align} 80,206 |
LNC |
Logical Observation Identifier Names and Codes, 232 |
| Unknown macro: {align} 41 |
MCM |
McMaster University Epidemiology Terms, 1992 |
| Unknown macro: {align} 331 |
MDBCAC |
Mitelman Database of Chromosome Aberrations in Cancer, 2005_12 |
| Unknown macro: {align} 47,210 |
MDR |
Medical Dictionary for Regulatory Activities Terminology, 14.0 |
| Unknown macro: {align} 1,897 |
MEDLINEPLUS |
MedlinePlus Health Topics, 20080614 |
| Unknown macro: {align} 900 |
MGED |
MGED Ontology, 131 |
| Unknown macro: {align} 310,485 |
MSH |
Medical Subject Headings, 2011_2010_08_30 |
| Unknown macro: {align} 85,138 |
MTH |
UMLS Metathesaurus, 2010AB |
| Unknown macro: {align} 19,880 |
MTHFDA |
Metathesaurus FDA National Drug Code Directory, 2010_08_02 |
| Unknown macro: {align} 337 |
MTHHH |
Metathesaurus HCPCS Hierarchical Terms, 2010 |
| Unknown macro: {align} 16,081 |
MTHICD9 |
International Classification of Diseases, Ninth Revision, Clinical Modification, Metathesaurus additional entry terms, 2011 |
| Unknown macro: {align} 94 |
MTHICPC2ICD107B |
ICPC2 - ICD10 Thesaurus, 7-bit Equivalents, 0412 |
| Unknown macro: {align} 76 |
MTHICPC2ICD10AE |
ICPC2 - ICD10 Thesaurus, American English Equivalents, 0412 |
| Unknown macro: {align} 1,633 |
MTHMST |
Metathesaurus Version of Minimal Standard Terminology Digestive Endoscopy, 2001 |
| Unknown macro: {align} 12,969 |
MTHSPL |
Metathesaurus FDA Structured Product Labels, 2010_08_27 |
| Unknown macro: {align} 478,187 |
NCBI |
NCBI Taxonomy, 2010_04_29 |
| Unknown macro: {align} 135 |
NCIMTH |
NCI Metathesaurus |
| Unknown macro: {align} 38,863 |
NDFRT |
National Drug File, 2010_09_07 |
| Unknown macro: {align} 1,781 |
NPO |
NPO: NanoParticle Ontology for Cancer Nanotechnology Research, 2010_10_31 |
| Unknown macro: {align} 63,924 |
OMIM |
Online Mendelian Inheritance in Man, 2010_04_08 |
| Unknown macro: {align} 9,869 |
PDQ |
Physician Data Query, 2010_08_06 |
| Unknown macro: {align} 2,041 |
PMA |
Portfolio Management Application, 2010 |
| Unknown macro: {align} 268 |
PNDS |
Perioperative Nursing Data Set, 2nd edition, 2002 |
| Unknown macro: {align} 940 |
QMR |
Quick Medical Reference (QMR), 1996 |
| Unknown macro: {align} 30,033 |
RADLEX |
RadLex, 3_33 |
| Unknown macro: {align} 227,498 |
RXNORM |
RxNorm Vocabulary, 10AA_100907F |
| Unknown macro: {align} 281,843 |
SNOMEDCT |
SNOMED Clinical Terms |
| Unknown macro: {align} 4,808 |
SPN |
Standard Product Nomenclature, 2003 |
| Unknown macro: {align} 156 |
SRC |
Metathesaurus Source Terminology Names |
| Unknown macro: {align} 13,788 |
UMD |
UMDNS: product category thesaurus, 2010 |
| Unknown macro: {align} 1,765 |
USPMG |
USP Model Guidelines, 2004 |
| Unknown macro: {align} 61,191 |
UWDA |
University of Washington Digital Anatomist, 1.7.3 |
| Unknown macro: {align} 26,546 |
VANDF |
Veterans Health Administration National Drug File, 2010_07_26 |
