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Managing Sample Composition Annotations | caNanoLab User's Guide| Managing Publications in caNanoLab

This section describes how to review or ascribe characterizations to samples save in caNanoLab. This section includes the following topics:

Curator Status

You can perform the procedures described in this section only if you are a curator. If you have read-only permissions, see Viewing a Characterization Summary.

[Sample] Characterization Overview

Sample characterization, describing distinctive characteristics or essential features of the sample determined through analytical methods, records information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by physical or chemical characteristics, or by data derived under in vitro and in vivo conditions.

Accessing a Sample Characterization

To access characterization functions in the Navigation Tree

  1. Perform a search for the sample.
  2. Click Edit in the search results row.
  3. The Navigation Tree appears on the left sidebar and comprises functions which you can use to add annotations to the sample.

    NAVIGATION TREE
    GENERAL INFO
    COMPOSITION
    CHARACTERIZATION
    PUBLICATION
    • General Info appears after you click the sample name and shows the Update Sample page.
    • Composition defines Nanomaterial Entity, Functionalizing Entity, and Chemical Associations.
    • Characterization defines essential physical characteristics that identify the material and structural properties via the Protocol and Physico-Chemical, In Vivo, and In Vitro Characterization.
    • Publication displays articles, books chapters, reviews and reports already added to a sample.

  4. Click the Characterizations link. 
  5. The All tab displays characterizations already added to the sample. The remaining tabs show annotations specific to those categories.

    Sample Characterization tabs with Add Selected on All page

    If you are a curator, you can review existing characterizations, as well as Add, Edit, Delete, Copy, Print, and Export. If you have read-only access, see see Viewing Characterizations Summary.

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Viewing a Characterization Summary

Sample characterizations describing distinctive characteristics or essential features of the sample determined through analytical methods, record information associated with sample synthesis and properties. Samples can be characterized in caNanoLab by Physico-chemical characterizatics, or by data derived under In vitro and In vivo conditions.

To view a sample characterizations summary

  1. Perform a search for the sample.
  2. Click Edit in the search results row.
  3. In the Navigation Tree on the left sidebar, click the Characterizations link. 
  4. The All tab displays characterizations already added to the sampe by category. Additional tabs show annotations added to the sample under their corresponding Physical, In Vitro and In Vivo Characterization subcategories.

    Read only permissions?

    Based on your security permissions, you may have read-only access to characterizations and only be able to see a characterization summary and not be able to perform additional tasks.

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Submitting Characterizations

Once you access Characterizations in the Navigation Tree, you can add different types of information to the sample.

If you have read-only access, you can  View a Characterizations Summary.

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Adding a Physico-Chemical Characterization

To add a physico-chemical characterization

  1. Access the characterization functions.
  2. Click the All or Physico-Chemical Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization Type* field.

  3. Follow these steps to fill in the characterization. Links are provided for additional details.

    SectionWhat to Do
    Physico-Chemical CharacterizationFill in the general information about the characterization.
    [Characterization] PropertiesDisplays only for Physical State, Shape and Solubility characterizations. Define properties for the characterization, if applicable.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.
    Copy to other Samples...Select samples in the list to which you want this physico-chemical data transferrred. This option copies files and data to one or more selected samples "owned" by the same point of contact.
  4. When you finish, click Submit to save the data to the sample.

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Defining the Physico-Chemical Characterization

To define the general information about the characterization

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

  1. The Characterization Type is already selected as Physico-Chemical Characterization.
  2. For the Characterization Name* select from the drop-down list the name of the Characterization you want to add (required).
  3. The Assay Type field populates automatically with your selection in the Characterization field.
  4. If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.
  5. For Characterization Source, select from the drop-down list or enter the source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
  6. In the Characterization Date field, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

Continue to define Physico-Chemical Properties.

Defining Physico-Chemical [Characterization] Properties

The [Characterization] Properties section opens only for the characterizations listed in the table below. The following table lists and describes the Properties fields.

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

CharacterizationProperty FieldsField Options

Physical State

Type

Select the appropriate type from among the following options:

Shape Properties

Type (required)

Select from the drop-down list the appropriate shape type:

Shape Properties

Aspect Ratio

Enter the shape aspect ratio.

Shape Properties

Minimum,/Maximum Dimensions

Enter the minimum and maximum dimensions of the sample, as well as the units of measurement.

Solubility Properties

Solvent

Select from the options or enter the name.

  • alcohol
  • phosphate-buffered saline
  • saline
  • water
 Solubility PropertiesCritical Concentration

Enter appropriate values for the critical concentration, then select the appropriate units for those values.

 Solubility PropertiesIs Soluble?Select Yes or No as to whether the solvent is soluble.

Surface Properties

Is Hydrophobic?

Indicate with Yes or No whether the surface is hydrophobic.

Continue to define Physico-Chemical Design and Methods.

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Defining Physico-Chemical Design and Methods

The following table lists and describes the Design and Methods fields.

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

Design and Methods FieldDescription

Description

Enter design and methods information not covered by other fields on the form.

Technique and Instrument

Click Add to expand the page where you can select and enter information regarding the technique and instrument used to derive the sample.

Technique*

Select the technique (required).

Abbreviation

When you select a technique, Abbreviation populates automatically if an abbreviation is known. If not, enter an abbreviation.

DescriptionEnter an appropriate description for the characterization design and methods.
Instrument

Click Add to expand the Instruments panel. Enter or select identifying information about the instrument used to obtain data.
  • Select the instrument Manufacturer.
  • Enter the instrument Model Name.
  • Enter the model Type.

Once you enter the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Continue to define Physico-Chemical Findings.

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Describing Findings for Physico-Chemical Characterization

In the Finding sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.

Click Add to expand the section, then add data and conditions and add a file.

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Adding Data and Conditions

In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information, such as laboratory conditions like pH or temperature that are part of your findings.

To define the data and condition matrix

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

  1. Add data values to Data and Conditions.
    1. To import a file of data values
      1. Save the spreadsheet of data values to a csv (comma-separated value) file.
      2. Click Import csv and select and follow the prompts to add the data file to the Findings Info.
        Import CSV button
      3. The columns and data are added to Data and Conditions.
    2. To add the data values manually
      1. Specify the number of columns and rows for the matrix, and click Update.
        Manually adding Data and Conditions data values
      2. Add the data values to the rows.

    Whether you imported or added information manually, you can preface each data value with one of the following: Maintain the default, equal to (=), or select greater than (>), less than (<), or infinity (approximate).
    Adding Data and Conditions values to the table

  2. To define a column, click an underlined column heading.
    Clicking column
    The Column Definition panel displays.
    Defining the Findings column definition
  1. Select a Column Type, Datum or Condition. 

  2. Select a Column Name or select other and add a new one.

    Column Notes

    You can add up to three cell viability Column Names, including cell viability, cell viability B, and cell viability C. You can further identify the column with the Column Value Type.
    1. For Column Type, Datum, the following characterization(s) display customized Column Name options.

      Characterization TypeColumn Type and Column Name Option(s)
      Physico-Chemical
      • MolecularMolecular Weight
      • Purity% purity for sample
      • RelaxivityR1, R2, T1, T2
      • SizePD1, Peak N , RMS size, Z Average
      • Surfacecharge, zeta potential
      In Vitro

      Enzyme Induction – % of Control

      In VivoClick Other to name the column yourself.
    2. For Column Type, Condition, all characterizations provide the Column Name options in the left column of the following table. The Column Name autopopulates the Condition Property options in the right column.

      Column Type, Condition Autopopulates Column NameColumn Name Autopopulates
      Condition Property

      Centrifugation

      N/A

      Culture Media

      media type, serum percentage

      Electromagnetic Radiation

      bandwidth, frequency, time, wavelength

      Freeze Thaw

      N/A

      Long Term Storage

      lyophilized, time

      Lyophilization

      time

      pH

      N/A

      Sample concentration

      N/A

      Short Term Storage

      lyophilized, time

      Solvent Media

      ion concentration, ionic strength, molecular formula, osmolality, serum percentage, with serum

      Sonication

      number of pulses, pulse duration

      Temperature

      N/A

  3. To further identify a column, select a Column Value Type.

    Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).


  4. Select a Column Value Unit, or select other and add one.
  5. If you want the same value to fill all rows in a column, add a Constant Value.

    For Column Value Type, boolean

    For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.
  6. Click Save, and the column(s) are updated.

    If needed, click Set Column Order to change the order of the column headings in the matrix.


  7. Click Save in the Finding section.


Column Type "Datum" is selected with this characterizationAutopopulated Column Name Option[s]

Molecular Weight

Molecular Weight

Purity

% purity for sample

Relaxivity

R1, R2, T1, T2

Size

PD1, Peak N , RMS size, Z Average

Surface

charge, surface area, zeta potential

    1. To further identify a column, select a Column Value Type.

      Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).
    2. Column Value Unit – Select a value unit, or select other and add one.
    3. Constant Value – If you want the same value to fill all rows in a column, add a constant value.

      For Column Value Type, boolean

      For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.

    4. Click Save, and the column(s) are updated.

      If needed, click Set Column Order to change the order of the column headings in the matrix.

  1. Click Save on the Finding Info panel.

After adding data and conditions to the sample, continue to add a Physico-Chemical Characterization.

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Adding a File

To add results in the form of supporting documents, such as a graphic, spreadsheet or images to a characterization
  1. In the Finding section, next to Files, click Add.
  2. Upload, browse, and select the file or enter the file's URL where the document is located.
  3. Complete the following.
    1. Select the File Type (required), Document, Graph, Image, Movie, or Spreadsheet.
    2. Enter the File Title (required).
    3. Specify Keywords to associate with the file
    4. Enter a Description of additional information of the file.
  4. Click Submit to add the file(s) to the sample.

You can add as many files as you wish.



After adding one or more files, add data and conditions or if you have no derived data to add, add a Physico-Chemical Characterization.

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Adding an In Vitro Characterization

In vitro characterization allows you to add characterizations for the nanomaterial component of the sample derived from analytical techniques performed under in vitro conditions.

To add an in vitro characterization

  1. Access the characterization functions.
  2. Click the All or In Vitro Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization* field.

  3. Follow these steps to fill in the characterization. Links are provided for additional details.

    Field/SectionWhat to Do
    In Vitro CharacterizationFill in the general information about the characterization.
    [Characterization] Properties]Displays only for Cytotoxicity, Enzyme Induction and Transfection in vitro characterizations. Define properties for the characterization, if applicable.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Finding

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.
    Copy to Other Samples...Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.
  4. When you finish, click Submit to save the data to the sample.

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Defining an In Vitro Characterization

To continue defining this characterization

  1. The Characterization Type is already selected as In Vitro Characterization.
  2. For the Characterization Name* select from the drop-down list the name of the Characterization you want to add (required).
  3. The Assay Type populates automatically with options that display only for these in vitro characterization selections: Blood Contact, Cytotoxicity, Immune Cell Function, Oxidative Stress, Sterility and Targeting. Select an option, if appropriate, or if there are none or if you prefer, select [Other] to name the assay type.
  4. If Protocol Name – Version is available, select from the drop-down list the protocol from which the data is derived. A hyperlink to the protocol text file should appear (if the protocol is not private to the user and the protocol file exists). However, protocol files are not required. Click the hyperlink to open or save the file.
  5. A hyperlink to the protocol text file should appear (if the protocol is not private to the user and the protocol file exists - ie. protocol files are not required).
  6. Select from the drop-down list or enter the Characterization Source from which the characterization data is derived, such as a vendor or a laboratory (NCL).
  7. In Characterization Date, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

    To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

    Continue to In Vitro Properties.

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Assay Type Options for In Vitro Characterizations

Specify one of the following in vitro Assay Type options or select [Other] to open a window where you can add a new assay type.

Return to Defining In Vitro Characterizations

Defining In Vitro [Characterization] Properties

The [Characterization] Properties section opens only when you select the following characterizations in the Summary section. To define properties for each unique characterization, enter information for the following fields.

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

  • For Cytotoxicity, enter the appropriate Cell Line.
  • For Enzyme Induction, enter your name of choice.
  • For Transfection, enter the appropriate Cell Line.

Continue to define In Vitro Design and Methods.

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Defining In Vitro Design and Methods

In the Design and Methods sections, complete the fields as described in the following table.

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

Design and Methods FieldDescription

Technique and Instrument

Click Add to expand the page where you can select and enter information regarding the technique and instrument used to derive the sample.

Technique*

Select the technique (required).

Abbreviation

When you select a technique, Abbreviation populates automatically if an abbreviation is known. If not, enter an abbreviation.

DescriptionEnter an appropriate description for the characterization design and methods.
Instrument

Click Add to expand the Instruments panel. Enter or select identifying information about the instrument used to obtain data.
  • Select the instrument Manufacturer.
  • Enter the instrument Model Name.
  • Enter the model Type.

Once you enter the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Continue to define In Vitro Findings.

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Describing Findings for an In Vitro Characterization

In the Finding sections, you can add one or more publications relevant to the sample, as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.

Click Add to expand the section, then add data and conditions and add a file.

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Adding Data and Conditions

In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information, such as laboratory conditions that are part of your findings.

To define the matrix for the data, follow these steps.

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

  1. Add data values to Data and Conditions.
    1. To import a file of data values
      1. Save the spreadsheet of data values to a csv (comma-separated value) file.
      2. Click Import csv and select and follow the prompts to add the data file to the Findings Info.
        Import CSV button
      3. The columns and data are added to Data and Conditions.
    2. To add the data values manually
      1. Specify the number of columns and rows for the matrix, and click Update.
        Manually adding Data and Conditions data values
      2. Add the data values to the rows.

    Whether you imported or added information manually, you can preface each data value with one of the following: Maintain the default, equal to (=), or select greater than (>), less than (<), or infinity (approximate).
    Adding Data and Conditions values to the table

  2. To define a column, click an underlined column heading.
    Clicking column
    The Column Definition panel displays.
    Defining the Findings column definition
  1. Select a Column Type, Datum or Condition. 

  2. Select a Column Name or select other and add a new one.

    Column Notes

    You can add up to three cell viability Column Names, including cell viability, cell viability B, and cell viability C. You can further identify the column with the Column Value Type.
    1. For Column Type, Datum, the following characterization(s) display customized Column Name options.

      Characterization TypeColumn Type and Column Name Option(s)
      Physico-Chemical
      • MolecularMolecular Weight
      • Purity% purity for sample
      • RelaxivityR1, R2, T1, T2
      • SizePD1, Peak N , RMS size, Z Average
      • Surfacecharge, zeta potential
      In Vitro

      Enzyme Induction – % of Control

      In VivoClick Other to name the column yourself.
    2. For Column Type, Condition, all characterizations provide the Column Name options in the left column of the following table. The Column Name autopopulates the Condition Property options in the right column.

      Column Type, Condition Autopopulates Column NameColumn Name Autopopulates
      Condition Property

      Centrifugation

      N/A

      Culture Media

      media type, serum percentage

      Electromagnetic Radiation

      bandwidth, frequency, time, wavelength

      Freeze Thaw

      N/A

      Long Term Storage

      lyophilized, time

      Lyophilization

      time

      pH

      N/A

      Sample concentration

      N/A

      Short Term Storage

      lyophilized, time

      Solvent Media

      ion concentration, ionic strength, molecular formula, osmolality, serum percentage, with serum

      Sonication

      number of pulses, pulse duration

      Temperature

      N/A

  3. To further identify a column, select a Column Value Type.

    Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).


  4. Select a Column Value Unit, or select other and add one.
  5. If you want the same value to fill all rows in a column, add a Constant Value.

    For Column Value Type, boolean

    For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.
  6. Click Save, and the column(s) are updated.

    If needed, click Set Column Order to change the order of the column headings in the matrix.


  7. Click Save in the Finding section.


Column Type "Datum" is selected with this characterizationAutopopulated Column Name Option[s]

Enzyme Induction

% of Control

    1. To further identify a column, select a Column Value Type.

      Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).
    2. Column Value Unit – Select a value unit, or select other and add one.
    3. Constant Value – If you want the same value to fill all rows in a column, add a constant value.

      For Column Value Type, boolean

      For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.

    4. Click Save, and the column(s) are updated.

      If needed, click Set Column Order to change the order of the column headings in the matrix.

  1. Click Save on the Finding Info panel.

After adding data and conditions to the sample, add an In Vitro Characterization.

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Adding a File

To add results in the form of supporting documents, such as a graphic, spreadsheet or images to a characterization
  1. In the Finding section, next to Files, click Add.
  2. Upload, browse, and select the file or enter the file's URL where the document is located.
  3. Complete the following.
    1. Select the File Type (required), Document, Graph, Image, Movie, or Spreadsheet.
    2. Enter the File Title (required).
    3. Specify Keywords to associate with the file
    4. Enter a Description of additional information of the file.
  4. Click Submit to add the file(s) to the sample.

You can add as many files as you wish.



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Adding an In Vivo Characterization

In vivo characterization allows you to add characterizations for the nanomaterial component of the sample that were derived from analytical techniques performed under in vivo conditions.

To add an in vivo characterization

  1. Access the characterization functions.
  2. Click the All or In Vivo Characterizations tab. Both tabs display five sections, but the All tab provide customizations based what you select in the Characterization* field.

  3. Follow these steps to fill in the characterization. Links are provided for additional details.

    Field/SectionWhat to Do
    In Vivo CharacterizationFill in the general information about the characterization.
    [Characterization] PropertiesDisplays for in vivo characterizations.
    Design and MethodsComplete the fields describing techniques and instruments used to derive the data.
    Findings

    Add data findings and supporting documentation relating to the sample.

    Analysis and ConclusionsEnter any relevant analyses and conclusions reached by the data.
    Copy to Other Samples...

    Select samples in the list to which you want this physico-chemical data transferred. This option copies files and data to one or more selected samples "owned" by the same point of contact.

  4. When you finish, click Submit to save the data to the sample.

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Defining an In Vivo Characterization

To define general information about the characterization

  1. The Characterization Type is already selected.
  2. For the Characterization Name*, select from the drop-down list the name of the Characterization you want to ad (required). The options for In Vivo Characterization are Pharmacokinetics and Toxicology. There are no customizations on this Characterization page based on either of these selections. 
  3. You can leave the Assay Type field blank or specify an Assay Type.
  4. If the Protocol Name – Version field is available, select from the drop-down list the protocol from which the data is derived. A hyperlink of the protocol text file may appear. Click the hyperlink to open or save the file.

    To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

  5. Select from the drop-down list or enter the Characterization Source from which the characterization data is derived, such as a vendor or a laboratory (NCL).

  6. In the Characterization Date field, select from the calendar or enter the date the characterization was made. Acceptable format: dd/mm/yyyy.

Defining In Vivo Design and Methods.

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Defining In Vivo Design and Methods

In the Design and Methods sections, complete the fields as described in the following table.

To enter an alternative to an option, select other if available and enter a value. The value is added to the list of options.

Design and Methods FieldDescription

Description

Enter information not covered by other fields on the form.

Technique and Instrument

Click Add to expand the page where you can select and enter information regarding the technique and instrument used to derive the sample.

Technique*

Select the technique (required).

Abbreviation

When you select a technique, Abbreviation populates automatically if an abbreviation is known. If not, enter an abbreviation.

DescriptionEnter an appropropriate description for the design and methods.
Instrument

Click Add to expand the Instruments panel. Enter or select identifying information about the instrument used to obtain data.
  • Select the instrument Manufacturer.
  • Enter the instrument Model Name.
  • Enter the model Type.

Once you specify the data, click Save to save the information to the sample or Cancel to close the mini-window without saving data.

Defining In Vivo Findings.

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Describing Findings for In Vivo Characterizations

In the Finding sections, you can add one or more publications relevant to the sample as well as data derived for the sample. You can add as many files and derived data as you wish, or you can add derived data without adding files.

Complete the instructions as described in Adding Data and Conditions and Adding a File.

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Adding Data and Conditions

In the Data and Conditions segment of the window, you can create a matrix where you can enter data values and/or other information that are part of your findings.

To define the matrix for the data

  1. Add data values to Data and Conditions.
    1. To import a file of data values
      1. Save the spreadsheet of data values to a csv (comma-separated value) file.
      2. Click Import csv and select and follow the prompts to add the data file to the Findings Info.
        Import CSV button
      3. The columns and data are added to Data and Conditions.
    2. To add the data values manually
      1. Specify the number of columns and rows for the matrix, and click Update.
        Manually adding Data and Conditions data values
      2. Add the data values to the rows.

    Whether you imported or added information manually, you can preface each data value with one of the following: Maintain the default, equal to (=), or select greater than (>), less than (<), or infinity (approximate).
    Adding Data and Conditions values to the table

  2. To define a column, click an underlined column heading.
    Clicking column
    The Column Definition panel displays.
    Defining the Findings column definition
  1. Select a Column Type, Datum or Condition. 

  2. Select a Column Name or select other and add a new one.

    Column Notes

    You can add up to three cell viability Column Names, including cell viability, cell viability B, and cell viability C. You can further identify the column with the Column Value Type.
    1. For Column Type, Datum, the following characterization(s) display customized Column Name options.

      Characterization TypeColumn Type and Column Name Option(s)
      Physico-Chemical
      • MolecularMolecular Weight
      • Purity% purity for sample
      • RelaxivityR1, R2, T1, T2
      • SizePD1, Peak N , RMS size, Z Average
      • Surfacecharge, zeta potential
      In Vitro

      Enzyme Induction – % of Control

      In VivoClick Other to name the column yourself.
    2. For Column Type, Condition, all characterizations provide the Column Name options in the left column of the following table. The Column Name autopopulates the Condition Property options in the right column.

      Column Type, Condition Autopopulates Column NameColumn Name Autopopulates
      Condition Property

      Centrifugation

      N/A

      Culture Media

      media type, serum percentage

      Electromagnetic Radiation

      bandwidth, frequency, time, wavelength

      Freeze Thaw

      N/A

      Long Term Storage

      lyophilized, time

      Lyophilization

      time

      pH

      N/A

      Sample concentration

      N/A

      Short Term Storage

      lyophilized, time

      Solvent Media

      ion concentration, ionic strength, molecular formula, osmolality, serum percentage, with serum

      Sonication

      number of pulses, pulse duration

      Temperature

      N/A

  3. To further identify a column, select a Column Value Type.

    Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).


  4. Select a Column Value Unit, or select other and add one.
  5. If you want the same value to fill all rows in a column, add a Constant Value.

    For Column Value Type, boolean

    For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.
  6. Click Save, and the column(s) are updated.

    If needed, click Set Column Order to change the order of the column headings in the matrix.


  7. Click Save in the Finding section.


For an in vivo characterization, click [Other] to name the column yourself.

    1. To further identify a column, select a Column Value Type.

      Once the column information is saved, the Column Type is shown in parentheses after the Column Name, such as cell viability (mean).
    2. Column Value Unit – Select a value unit, or select other and add one.
    3. Constant Value – If you want the same value to fill all rows in a column, add a constant value.

      For Column Value Type, boolean

      For Column Value Type, boolean, enter a Constant Value of 1 for true and 0 for false.

    4. Click Save, and the column(s) are updated.

      If needed, click Set Column Order to change the order of the column headings in the matrix.

  1. Click Save on the Finding Info panel.

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Adding a File

To add results in the form of supporting documents, such as a graphic, spreadsheet or images to a characterization
  1. In the Finding section, next to Files, click Add.
  2. Upload, browse, and select the file or enter the file's URL where the document is located.
  3. Complete the following.
    1. Select the File Type (required), Document, Graph, Image, Movie, or Spreadsheet.
    2. Enter the File Title (required).
    3. Specify Keywords to associate with the file
    4. Enter a Description of additional information of the file.
  4. Click Submit to add the file(s) to the sample.

You can add as many files as you wish.



After adding one or more files, continue by Adding Data and Conditions or if you have no derived data to add, return to the steps described in Adding an In Vivo Characterization.

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Characterization Tasks

From a characterization summary page, and with curator privileges, you can perform these tasks:

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Printing a Characterization

To print a characterization

  1. Open the sample of your choice.
  2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
  3. Click the Print hyperlink at the top right of the page.

    Read only access?

    If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Exporting Characterizations

To export a characterization

  1. Open the sample of your choice.
  2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
  3. Click the Export hyperlink at the top right of the page.

    Read only access?

    If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Editing Characterizations

To edit a characterization

  1. Open the sample of your choice.
  2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
  3. Click the Edit hyperlink at the right of the characterization section you want to change. This opens the corresponding Characterization page where you can edit the file by following the same directions as described for creating characterizations.

    Read only access?

    If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Copying Characterizations

The characterization files and/or derived data for this sample can be copied to other samples from the same primary point of contact.

To copy characterizations, open the sample characterization form that displays the characterization

  1. Open the sample of your choice.
  2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
  3. On the characterization summary page, click the Edit hyperlink at the right of the section you want to copy. This opens the corresponding Characterization page.
  4. At the bottom of the page, in the Copy to other samples... box, select one or more samples that have the same primary point of contact (those listed).
  5. Click the Also copy characterization results? box.
  6. Click Submit to execute the copy function.

    Read only access?

    If buttons described in this section do not display, then you can assume that you have read-only access to the data.

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Deleting a Characterization

To delete a characterization for a selected sample

Deleting a characterization

This only deletes the characterization(s) for the selected sample. If the characterization(s) is copied for other samples, the characterization will not be deleted.

  1. Open the sample of your choice.
  2. In the Navigation Tree on the left sidebar, click the Characterizations button. The All tab displays the characterizations summary.
  3. Click the Edit hyperlink at the right of the section you want to delete. This opens the corresponding Characterization page.
  4. Click the Delete button at the bottom left of the page.

    Read only access?

    If buttons described in this section do not display, then you can assume that you have read-only access to the data.

Deleted characterizations are placed in the sample archive for history purposes.

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Publication Tasks Associated with a Sample

Click the Publications button on the Navigation Tree. A Publication[s] summary page displays those publications associated with the sample, and the publication identifier, title, authors and year, where appropriate. Additionally, each publication category tab displays its corresponding publications.

Either on the Publications All tab or the subcategory tabs, you can

  • Access a publication, click the Abstract/Download hyperlink. This opens the document.
  • Add a publication to the open sample, click the Add button corresponding to the publication type on the All tab or select a publication type tab and click the Add button. This opens the Submit Publication page identical to that opened from the Publications menu option with one exception:

If you work from the Publications menu option, you can associate multiple samples with a publication. Alternatively, if you add publications to an open sample using the Navigation Tree option, you can use the copy feature to associate the publication with other samples in the same way you copy characterizations to multiple samples. See Copying Characterizations.

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Managing Sample Composition Annotations | caNanoLab User's Guide| Managing Publications in caNanoLab

 

 

Read only permissions?

Based on your security permissions, you may have read-only access to characterizations and only be able to see a characterization summary and not be able to perform additional tasks.

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