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Chair:
Luigi Ferrucci M.D., Ph.D., National Institute on Aging
Co-chairs
Gabriela Riscuta M.D., C.N.S., National Cancer Institute
Konstantin Salnikow Ph.D., National Cancer Institute
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Up-coming conference Registration
Age-Dependent Changes in Cancer Biology
October 26-27, 2020
Virtual Conference
The conference is organized in collaboration of National Cancer Institute, National Institute on Aging and National Institute of Environmental Health Sciences. It was announced for an in-person meeting ( April 2-3, 2020) and it is being rescheduled to a virtual meeting due to COVID-19.
Draft Agenda
Day 1, October 26, 2020
10:00 am – 10:05 am | Introduction and Overview Gabriela Riscuta NCI/DCP | ||
10:05 am -10:20 am | Opening Remarks: Ned Sharpless NCI | ||
10:20 am - 10:35 am | Opening Remarks: Richard Hodes NIA | ||
10:35 am -11:05 am | Keynote Speaker: Luigi Ferrucci, NIA | ||
11:05 am - 11:45 am | Understanding the Molecular Biology of Cancer in Elderly Moderator: Max Guo NIA | ||
11:05 am -11:25 am | Anticancer mechanisms in long-lived mammals Vera Gorbunova (University of Rochester) (DAB/NIA) | ||
11:25 am -11:45 am | Connecting cancer to aging – an evolutionary perspective James V. Degregori (University of Colorado) (DAB/NIA) | ||
11:45 am -12:05 pm | Panel Discussion | ||
12: 05 pm - 12:25 pm | Lunch | ||
12: 25 pm - 1:05 pm 12:25 pm-12:45 pm 12: 45 pm -1:05 pm | Cellular Senescence in Cancer and Aging Moderator: Basil Eldadah, NIA Mechanisms of immunosenescence and Immune response to vaccines in elderly Nan-Ping Weng (Laboratory of Molecular Biology and Immunology, LMBI, NIA/IRP) Cellular senescence in aging and cancer Darren Baker (Mayo Clinic) | ||
1:05 pm – 1:25 pm | Panel Discussion | ||
1:25 pm - 2:10 pm
| Implication of Oxidative Stress Towards Cancer Biology Moderator: Konstantin Salnikow, DCB/NCI | ||
1: 25 pm - 1: 45 pm | Gender effects in cancer and aging Vadim Gladyshev (Brigham and Women’s Hospital, Harvard Medical School) | ||
1:45 pm – 2:05 pm | Dysregulation of iron metabolism in cancer and aging Suzy Torti (University of Connecticut) | ||
2:05 pm - 2:25 pm | Panel Discussion | ||
2: 25 pm - 2:30 pm | Coffee break | ||
2:30 pm – 3:10 pm | Senescence, Immune Response and Cancer in the Elderly Moderators: Matt Young and Anil Wali, NCI
| ||
3: 10pm -3: 30 pm | Panel Discussion | ||
3: 30 pm - 4: 30 pm 3: 30- 3:50 Pm 3:50- 4:10pm | Environmental Factors: the Overlap of Carcinogens/Gerontogens Moderator: Les Reinlib NIEHS Environmental genomics of breast and prostate cancer Susan Neuhausen (City of Hope) ( NIEHS)
Breast Cancer in young & older women; Lead, Carolina Breast Cancer Study; co-I, African American Breast Cancer Epidemiology and Risk (AMBER); Cancer Genome Atlas Melissa Troester, UNC CH (NIEHS) | ||
Day 2, October 27, 2020
10:00 am - 10: 10 am | Goals and Objectives Konstantin Salnikow Ph.D. NCI |
10:10 am - 10:40 am | Keynote: Epigenetic linkage of aging, cancer and nutrition Trygve Tollefsbol (University of Alabama) (DCP/NCI) |
10:40 am - 11:50 am | Potential Impact of Nutrition on Cancer Prevention Moderator : Gabriela Riscuta and Pat Prasanna |
10:40 am -11:00 am
| Senolytic bioactive food components and their biological pathway for action Simmin Meydani (Tufts University) (DCP/NCI)
|
11:00-11:20 am | Cancer prevention in elderly and particularities for mechanisms of action Chengguo Xing (University of Florida) (DCP/NCI) |
11:20 am - 11:50 am | The mechanisms of fasting and advanced glycation end products in cancer prevention in elderly Sebastian Brandhorst (University of Southern California) (DCP/NCI) |
11:50 am -12:10 am | Panel Discussion |
12:10-12:30 pm | Lunch Break |
12:30 pm - 1:00 pm | Keynote speaker: Jan Van Duersen (Mayo Clinic) |
1:00 pm - 2:00 pm | Cancer Therapeutics and Treatment Optimization for the Elderly Moderators: Weiwei Chen and Christina Liu |
1:00 pm- 1:20 pm
| Improvement of cancer therapy by exploiting cellular senescence Judith Campisi (Buck Institute for Research on Aging) (DCTD/NCI) |
1:20 pm - 1:40 pm | The development of AI-enhanced cardiac MRI to address cardiotoxicity in elderly Multiple Myeloma patients Greg Lanza (Washington University at St. Louis) ( NCI/DCTD) |
1:40 pm - 2:00 pm | Treatment Optimization for the elderly with comorbidities Heidi Klepin (Wake Forest) (NCI/DCTD) |
2:00 pm - 2: 20 pm | Panel Discussion |
2:20- 2:30 pm | Wrap Up and Adjourn |
Planning Committee
Luigi Ferrucci (NIA) Chair
Gabriela Riscuta (NCI/DCP); co-chair
Konstantin Salnikow (NCI/DCB); co-chair
Nelson Aguila (NIH/NCI)
Weiwei Chen (NIH/NCI)
Basil Eldadah ( NIA)
Max Guo (NIH/NIA/ERP)
Christina Liu (NIH/NCI)
Pat Prasana ( NIH/NCI/DCTD)
Leslie Reinlib (NIH/NIEHS)
Sudhir Srivastava (NIH/NCI/DCP)
Anil Wali (NIH/NCI)
Matthew Young (NIH/NCI/DCP)
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