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Chair:
Luigi Ferrucci M.D., Ph.D., National Institute on Aging
Co-chairs
Gabriela Riscuta M.D., C.N.S., National Cancer Institute
Konstantin Salnikow Ph.D., National Cancer Institute
Useful Links:
Click here to subscribe to CAIG listserv
National Institute on Aging: https://www.nia.nih.gov/research/labs
For information on Clinical Trials, please visit:
https://www.nia.nih.gov/research/clinical-trials
For information on the Baltimore Longitudinal Study of Aging (BLSA), please visit:
https://www.nia.nih.gov/research/labs/blsa/join-blsa
If interested in participating in a clinical trial, please contact the NIA recruitment line at 410-350-3941 or email NIAStudiesRecruitment@mail.nih.gov
NIH corner ( restricted access for NIH people using their PIV card and password).
Up-coming conference Registration
Age-Dependent Changes in Cancer Biology
October 26-27, 2020
Virtual Conference
The conference is organized in collaboration of National Cancer Institute, National Institute on Aging and National Institute of Environmental Health Sciences. It was announced for an in-person meeting ( April 2-3, 2020) and it is being rescheduled to a virtual meeting due to COVID-19.
Draft Agenda
Day 1, October 26, 2020
10:00 am – 10:05 am | Introduction and Overview Gabriela Riscuta NCI |
10:05 am -10:20 am | Opening Remarks: Ned Sharpless NCI |
10:20 am - 10:35 am | Opening Remarks: Richard Hodes, M.D., NIA |
10:35 am -11:05 am | Keynote Speaker: Luigi Ferrucci, M.D., Ph.D., NIA/IRP |
11:05 am - 11:45 am | Understanding the Molecular Biology of Cancer in Elderly Moderator: Max Guo NIA |
11:05 am -11:25 am | Anticancer mechanisms in long-lived mammals Vera Gorbunova (University of Rochester) (DAB/NIA) |
11:25 am -11:45 am | Connecting cancer to aging – an evolutionary perspective James V. Degregori (University of Colorado) (DAB/NIA) |
11:45 am -12:05 pm | Panel Discussion |
12: 05 pm - 12:25 pm | Lunch |
12: 25 pm - 1:05 pm 12:25 pm-12:45 pm 12: 45 pm -1:05 pm | Cellular Senescence in Cancer and Aging Moderator: Basil Eldadah, M.D., Ph.D., NIA Mechanisms of immunosenescence and Immune response to vaccines in elderly Nan-Ping Weng, M.D., Ph.D., (Laboratory of Molecular Biology and Immunology, LMBI, NIA/IRP) Cellular senescence in aging and cancer Darren Baker, Ph.D. (Mayo Clinic) |
1:05 pm – 1:25 pm | Panel Discussion |
1:25 pm - 2:05 pm 1: 25 pm - 1: 45 pm 1:45 pm – 2:05 pm
| Implication of Oxidative Stress Towards Cancer Biology Moderator: Konstantin Salnikow, Ph.D., NCI Gender effects in cancer and aging Vadim Gladyshev (Brigham and Women’s Hospital, Harvard Medical School) Dysregulation of iron metabolism in cancer and aging Suzy Torti (University of Connecticut) |
2:05 pm - 2:25 pm | Panel Discussion |
2: 25 pm - 2:30 pm | Coffee break |
2:30 pm – 3:10 pm 2:30 pm - 2:50 pm 2:50 pm - 3:10 pm | Senescence, Immune Response and Cancer in the Elderly Moderators: Matt Young and Anil Wali, NCI Telomere and genome integrity in cancer and aging Patricia Opresko University of Pittsburgh (NCI) Inter-relationship between microbiota diversity, obesity and race in endometrial cancer Victoria Lin Bae-Jump (University of North Carolina, Chapel Hill) |
3: 10 pm - 3: 30 pm | Panel Discussion |
3: 30 pm - 4: 30 pm 3: 30 pm - 3:50 pm 3:50 pm - 4:10 pm | Environmental Factors: the Overlap of Carcinogens/Gerontogens Moderator: Les Reinlib NIEHS Environmental genomics of breast and prostate cancer Susan Neuhausen (City of Hope) ( NIEHS) Breast Cancer in young & older women Lead, Carolina Breast Cancer Study; co-I, African American Breast Cancer Epidemiology and Risk (AMBER); Cancer Genome Atlas Melissa Troester, UNC CH (NIEHS) |
4:10 pm - 4:30 pm | Panel Discussion |
| 4:30 pm | Adjourn |
Day 2, October 27, 2020
10:00 am - 10: 10 am | Goals and Objectives Konstantin Salnikow Ph.D. NCI |
10:10 am - 10:40 am | Keynote: Epigenetic linkage of aging, cancer and nutrition Trygve Tollefsbol (University of Alabama) (DCP/NCI) |
10:40 am - 11:50 am 10:40 am - 11:00 am 11:00 am - 11:20 am 11:20 am - 11:50 am | Potential Impact of Nutrition on Cancer Prevention Moderator: Gabriela Riscuta and Pat Prasanna, NCI Senolytic bioactive food components and their biological pathway for action Simmin Meydani (Tufts University) (DCP/NCI) Cancer prevention in elderly and particularities for mechanisms of action Chengguo Xing (University of Florida) (DCP/NCI) The mechanisms of fasting and advanced glycation end products in cancer prevention in elderly Sebastian Brandhorst (University of Southern California) (DCP/NCI) |
11:50 am -12:10 pm | Panel Discussion |
12:10 pm - 12:30 pm | Lunch Break |
12:30 pm - 1:00 pm | Keynote speaker: Dr. Sean Morrison (UT Southwestern ) |
1:00 pm - 2:00 pm | Cancer Therapeutics and Treatment Optimization for the Elderly Moderators: Weiwei Chen and Christina Liu, NCI |
1:00 pm - 1:20 pm
| Improvement of cancer therapy by exploiting cellular senescence Judith Campisi (Buck Institute for Research on Aging) (DCTD/NCI) |
1:20 pm - 1:40 pm | The development of AI-enhanced cardiac MRI to address cardiotoxicity in elderly Multiple Myeloma patients Greg Lanza (Washington University at St. Louis) ( NCI/DCTD) |
1:40 pm - 2:00 pm | Treatment Optimization for the elderly with comorbidities Heidi Klepin (Wake Forest) (NCI/DCTD) |
2:00 pm - 2: 20 pm | Panel Discussion |
2:20 pm - 2:30 pm | Wrap Up and Adjourn |
Planning Committee:
Luigi Ferrucci (NIA) Chair
Gabriela Riscuta (NCI/DCP); co-chair
Konstantin Salnikow (NCI/DCB); co-chair
Nelson Aguila (NIH/NCI)
Weiwei Chen (NIH/NCI)
Basil Eldadah ( NIA)
Max Guo (NIH/NIA/ERP)
Christina Liu (NIH/NCI)
Pat Prasana ( NIH/NCI/DCTD)
Leslie Reinlib (NIH/NIEHS)
Sudhir Srivastava (NIH/NCI/DCP)
Anil Wali (NIH/NCI)
Matthew Young (NIH/NCI/DCP)
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