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Summary

On presenting the ACRIN proposal to conduct the CTC trial to the NCI Executive Committee, a case was made that image data sharing, publicly accessible by the National Biomedical Image Archive (NBIA) would be an invaluable research asset to the image processing research community. Adding to the many merits of that proposal, the data-sharing component was strongly endorsed. ACRIN completed the trial expeditiously and its results were published in NEJM in fall 2008 to wide interest (N Engl J Med. 2008 Sep 18;359(12):1207-17). The ACRIN website has a more complete protocol description (http://www.acrin.org/TabID/151/Default.aspx). ACRIN has graciously permitted a wider research community access to a portion of the data from that trial.

The "CT Colonography" (CTC) image collection in DICOM format, PHI de-identified for public download https://imaging.nci.nih.gov/ncia/  contains 825 cases from optical colonoscopy (OC)-validated subjects who had same-day sequential CTC followed by OC. The attached documents separately lists OC verified cases that contain: 243 Cases where no polyp was found; 69 cases possessing 6 to 9 mm polyps; and 35 cases that possess at least one polyp "larger than 10 mm." The key to the lesion coding in those XL files is: CTC key to XL colon lesion spreadsheet.docx

Data Access

Collection Statistics

 

Modalities

CT

Number of Patients

825

Number of Studies

836

Number of Series

3,451

Number of Images

941,774

You can view and download these images on NBIA. You do not need to log in unless you want access to advanced features in the site. Simply follow these steps:

  • Navigate to http://imaging.nci.nih.gov
  • Click the "Search Images" link in the center of the page
  • Scroll down through the search criteria until you see the "Collections" section
  • Select the "CT Colonography" check box
  • Press "Submit"

This will return the full list of cases included in the collection. To download the associated DICOM images:

  • Press the "Check All" button and then "Add to Basket"
  • Press the "View My Basket" button at the bottom of the page (or "View Contents" in the left menu bar)
  • Press the "Download Manager" button to open a Java applet and specify where you'd like to save your images
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