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The caBIG® consortium is a partnership of government, academic, and industry stakeholders in health care, both nationally and internationally. Due to the successes of the caBIG® program, the stakeholder community has broadened to include BIGHealth and the NHIN, as well as the familiar communities involved in fighting cancer. These researchers, providers, patients, advocates, payers, product innovators, investors, and information technologists have come together in a novel organizational framework to make real the new paradigm of personalized medicine and integrated care.