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caArray is supported by the Molecular Analysis Tools Knowledge Center.

For more information on receiving support for this tool, please visit the Molecular Analysis Tools Knowledge Center.

Tool Overview

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caArray logo caArray is an open-source, web and programmatically accessible array data management system. caArray guides the annotation and exchange of array data using a federated model of local installations whose results are shareable across the cancer Biomedical Informatics Grid (caBIG®). caArray furthers translational cancer research through acquisition, dissemination and aggregation of semantically interoperable array data to support subsequent analysis by tools and services on and off the Grid. As array technology advances and matures, caArray will extend its logical library of assay management.

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What's New

caArray 2.4.1 was officially released on 10/3/2011 and is available on the NCI CBIIT production server.

For more news, visit What's new for caArray.

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At A Glance Details

Current Version Number: 2.4.1
Release Date of Current Version: Oct 2011
Intended Audiences: Microarray data producers and application developers
Primary Workspace: ICR
Currently caGrid Enabled? Yes
caBIG® Compatiblity Level: Silver Compatibility (5/28/2009)

caArray Public Server

A public caArray hosted by NCI is free to community. A free account will be issued upon registration.

Technical Information

Tool Maturity Assessment: Stable Release (Adoption in Progress)

Installation Level: Intermediate - technical assistance may be required, download may require supporting infrastructure or software

System Requirements

While caArray is a web-based application, it does have a dependent software stack, which includes: MySQL 5.0.27 database; JBoss 4.0.4 (hosts the caArray grid service) and JBoss 4.0.5 (hosts the caArray application); JEMS installer 1.0.2 GA (supports EJB 3.0 specification)

Dependent Software

Version

URL

J2SE Development Kit

5.0 Update 10 (J2SE 5.0)

J2SE 5.0

Apache Ant

1.7.0

apache-ant-1.7.0-bin.zip

MySQL

5.0.27

mysql 5.0.27

JBoss for UPT

4.04

JBOSS for Grid Service

4.04

JBOSS for caArray application

4.05

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Presentations, Demos and Other Materials

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Documentation, Meetings and Training

caArray Meetings and Plans

caArray Documentation

End User

Technical

Download and Sample Data

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caArray Knowledge Base

caArray FAQ and In-depth Articles

Find the answers to the most frequently asked questions; understand how caArray works.

caArray Demos

caArray Demos provides a collection of short videos and slide presentations to demonstrate specific aspects of caArray.

caArray Case Studies

If you still don't know if caArray is for you, explore the caArray Case Studies. Case studies show examples of how caArray could be used in different scenarios.

caArray Citations

For a list of articles that discuss caArray, visit caArray Citations.

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Installation and Downloads

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Forum and Support for caArray

Forum

Support

Archived Info

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Submit defects and feature requests for caArray

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Open-source development

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Integration with other tools

Integration with geWorkbench

geWorkbench can query for data in an instance of caArray via a Java API. Several operations are supported. You can:

  1. Query for experiments, for example by platform or by species.
  2. Select from which hybridizations in an experiment you wish to download data.
  3. Download derived (summarized, probeset-level) data that has been parsed into the database. An example is the values loaded from Affymetrix CHP files (created through GCOS/MAS5). geWorkbench does not currently support retrieving or analyzing Affy CEL files directly.

The current release of geWorkbench, version 2.1.0, connects with caArray 2.3.0, 2.3.1, and 2.4.0.2
For more information, visit the geWorkbench project page.

The software can be downloaded.

Integration with caIntegrator

caIntegrator can extract the genomic data from caArray hosted on either a private server or the NCI site. You can:

  1. Extract the genomic data into caIntegrator.
  2. Integrate the genomic data with the clinical data and imaging data in caIntegrator.
  3. Perform genomic data analysis with the built-in GenePattern Tool within caIntegrator.

The current release of caIntegrator, version 1.2.0, can work with caArray 2.3.0, 2.3.1, and 2.4.0.2 .

You may use the publicly accessible NCI site. To install a local copy, download a copy of software.

Integration with GenePattern

GenePattern has a module that can retrieve data from caArray using its Java API. The caArray2.3.0 Importer lets you retrieve raw data files from caArray by experiment name or id. You can specify the extension of the data file that you want to download. The default is .CEL.

You can process CEL files using the GenePattern module ExpressionFileCreator. Once you have used ExpressionFileCreator, the data can be further analyzed using many different GenePattern analysis modules.

The caArray 2.3.0 Importer module is compatible with caArray v2.3.x. You may download the caArray2.3.0Importer.

The caArray 2.1.0 Importer module is compatible with caArray v2.1.x and v2.2.0. You may download the caArray2.1.0Importer.

You may also download GenePattern.

Once you've fetched your microarray data from caArray from any of the above versions of the caArrayImporter, you can use that data in any GenePattern module or pipeline that accepts gene expression data. To view compatible modules from within GenePattern you can click the context arrow next to the imported file (the result file of your caArrayImporter job in Recent Jobs) to see which modules can accept this dataset.

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